| 1 | Mon Nov 4 | at Loyola Chicago | L72-79 | 0-1 | .000 | - | ESPN+ | Joseph J. Gentile Arena · Chicago, IL |
| 2 | Sat Nov 9 | vs Youngstown St | L60-80 | 0-2 | .000 | - | | Jones Convocation Center · Chicago, IL |
| 3 | Tue Nov 12 | at Texas | L58-105 | 0-3 | .000 | - | ESPN+ | Moody Center · Austin, TX |
| 4 | Sat Nov 16 | at San Francisco | L37-82 | 0-4 | .000 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
| 5 | Tue Nov 19 | vs E Kentucky | L66-86 | 0-5 | .000 | - | | Jones Convocation Center · Chicago, IL |
| 6 | Fri Nov 22 | at Indiana St | L61-97 | 0-6 | .000 | - | ESPN+ | Hulman Center · Terre Haute, IN |
| 7 | Mon Nov 25 | vs Radford | L48-63 | 0-7 | .000 | - | | Jones Convocation Center · Chicago, IL |
| 8 | Tue Nov 26 | vs Drexel | L71-83 | 0-8 | .000 | - | | Jones Convocation Center · Chicago, IL |
| 9 | Sat Nov 30 | at #15Wisconsin | L53-74 | 0-9 | .000 | - | Peacock | Kohl Center · Madison, WI |
| 10 | Mon Dec 2 | at St Thomas (MN) | L76-98 | 0-10 | .000 | - | | Schoenecker Arena · Saint Paul, MN |
| 11 | Sun Dec 8 | at Saint Louis | L62-85 | 0-11 | .000 | - | ESPN+ | Chaifetz Arena · St. Louis, MO |
| 12 | Sun Dec 15 | at Mercer | L63-75 | 0-12 | .000 | - | ESPN+ | Hawkins Arena · Macon, GA |
| 13 | Thu Dec 19 | at Grand Canyon | L51-74 | 0-13 | .000 | - | ESPN+ | GCU Arena · Phoenix, AZ |
| 14 | Sat Dec 21 | at CSU Northridge | L57-81 | 0-14 | .000 | - | ESPN+ | Premier America Credit Union Arena · Northridge, CA |
| 15 | Sun Dec 29 | at #24Illinois | L64-117 | 0-15 | .000 | - | BTN | State Farm Center · Champaign, IL |
| 16 | Fri Jan 3 | at Wagner | W64-52 | 1-15 | .063 | - | | Spiro Sports Center · Staten Island, NY |
| 17 | Sun Jan 5 | at Long Island | L39-53 | 1-16 | .059 | - | | Steinberg Wellness Center · Brooklyn, NY |
| 18 | Sun Jan 12 | vs Stonehill | L52-68 | 1-17 | .056 | - | | Jones Convocation Center · Chicago, IL |
| 19 | Sat Jan 18 | vs Le Moyne | W88-72 | 2-17 | .105 | - | | Jones Convocation Center · Chicago, IL |
| 20 | Mon Jan 20 | vs Fairleigh | L48-58 | 2-18 | .100 | - | | Jones Convocation Center · Chicago, IL |
| 21 | Fri Jan 24 | atStonehill | L73-75 | 2-19 | .095 | - | | placeholder · sf, ca |
| 22 | Sun Jan 26 | at C Connecticut | L64-81 | 2-20 | .091 | - | | William H. Detrick Gymnasium · New Britain, CT |
| 23 | Sat Feb 1 | vsLong Island | W73-67 (OT) | 3-20 | .130 | - | | Jones Convocation Center · Chicago, IL |
| 24 | Thu Feb 6 | vs Mercyhurst | W85-78 | 4-20 | .167 | - | | Jones Convocation Center · Chicago, IL |
| 25 | Sat Feb 8 | vs St Francis PA | L69-81 | 4-21 | .160 | - | ESPN+ | Jones Convocation Center · Chicago, IL |
| 26 | Thu Feb 13 | atFairleigh | L49-91 | 4-22 | .154 | - | | Stratis Arena at the Rothman Center · Teaneck, NJ |
| 27 | Sat Feb 15 | atLe Moyne | L75-80 | 4-23 | .148 | - | | Ted Grant Court · Syracuse, NY |
| 28 | Thu Feb 20 | vsC Connecticut | L75-81 | 4-24 | .143 | - | | Jones Convocation Center · Chicago, IL |
| 29 | Sat Feb 22 | vsWagner | L52-64 | 4-25 | .138 | - | | Jones Convocation Center · Chicago, IL |
| 30 | Thu Feb 27 | atMercyhurst | L68-90 | 4-26 | .133 | - | | Mercyhurst Athletic Center · Erie, PA |
| 31 | Sat Mar 1 | atSt Francis PA | L71-80 (OT) | 4-27 | .129 | - | | DeGol Arena · Loretto, PA |
| 32 | Wed Mar 5 | atLong Island | L57-68 | 4-28 | .125 | - | ESPN+ | Steinberg Wellness Center · Brooklyn, NY |
