| 1 | Mon Nov 4 | at Syracuse | L82-86 | 9-19 | .321 | - | ESPN+ | JMA Wireless Dome · Syracuse, NY |
| 2 | Wed Nov 6 | vs CSU Northridge | L75-97 | 0-2 | .000 | - | | Ted Grant Court · Syracuse, NY |
| 3 | Sat Nov 9 | vs TBD | W107-73 | 1-2 | .333 | - | | Ted Grant Court · Syracuse, NY |
| 4 | Wed Nov 13 | at #3UConn | L49-90 | 1-3 | .250 | - | FS1 | Gampel Pavilion · Storrs, CT |
| 5 | Sat Nov 16 | at St Bonaventure | L52-71 | 1-4 | .200 | - | ESPN+ | Reilly Center · Saint Bonaventure, NY |
| 6 | Fri Nov 22 | vs UT Martin | W65-53 | 2-4 | .333 | - | ESPN+ | Ted Grant Court · Syracuse, NY |
| 7 | Sat Nov 23 | at Texas A&M-CC | L61-82 | 2-5 | .286 | - | ESPN+ | American Bank Center · Corpus Christi, TX |
| 8 | Mon Nov 25 | at UT Rio Grande | L77-97 | 2-6 | .250 | - | ESPN+ | UTRGV Fieldhouse · Edinburg, TX |
| 9 | Fri Nov 29 | at Manhattan | W81-77 | 3-6 | .333 | - | ESPN+ | Draddy Gymnasium · Riverdale, NY |
| 10 | Tue Dec 3 | vs Army | L100-103 (3OT) | 3-7 | .300 | - | | Ted Grant Court · Syracuse, NY |
| 11 | Sat Dec 7 | vs Binghamton | L62-72 | 3-8 | .273 | - | | Ted Grant Court · Syracuse, NY |
| 12 | Sat Dec 14 | vsTBD | W106-51 | 4-8 | .333 | - | | Ted Grant Court · Syracuse, NY |
| 13 | Wed Dec 18 | at Dartmouth | W80-76 | 5-8 | .385 | - | ESPN+ | Edward Leede Arena · Hanover, NH |
| 14 | Sun Dec 22 | at Notre Dame | L62-91 | 5-9 | .357 | - | ACC Network | Purcell Pavilion · South Bend, IN |
| 15 | Sun Dec 29 | at Niagara | L69-88 | 5-10 | .333 | - | ESPN+ | Gallagher Center · Niagara Falls, NY |
| 16 | Fri Jan 3 | at Long Island | L62-78 | 5-11 | .313 | - | | Steinberg Wellness Center · Brooklyn, NY |
| 17 | Fri Jan 10 | vs Fairleigh | L86-91 (2OT) | 5-12 | .294 | - | | Ted Grant Court · Syracuse, NY |
| 18 | Sun Jan 12 | vs Mercyhurst | W79-63 | 6-12 | .333 | - | | Ted Grant Court · Syracuse, NY |
| 19 | Sat Jan 18 | at Chicago St | L72-88 | 6-13 | .316 | - | | Jones Convocation Center · Chicago, IL |
| 20 | Mon Jan 20 | vs Stonehill | W73-72 | 7-13 | .350 | - | | Ted Grant Court · Syracuse, NY |
| 21 | Fri Jan 24 | vs C Connecticut | L70-93 | 7-14 | .333 | - | | Ted Grant Court · Syracuse, NY |
| 22 | Thu Jan 30 | atFairleigh | L74-78 | 7-15 | .318 | - | | Stratis Arena at the Rothman Center · Teaneck, NJ |
| 23 | Sat Feb 1 | at Wagner | L61-73 | 7-16 | .304 | - | | Spiro Sports Center · Staten Island, NY |
| 24 | Thu Feb 6 | at St Francis PA | L78-86 | 7-17 | .292 | - | | DeGol Arena · Loretto, PA |
| 25 | Sat Feb 8 | atMercyhurst | L78-82 | 7-18 | .280 | - | | Mercyhurst Athletic Center · Erie, PA |
| 26 | Thu Feb 13 | vsWagner | W72-68 (OT) | 8-18 | .308 | - | | Ted Grant Court · Syracuse, NY |
| 27 | Sat Feb 15 | vsChicago St | W80-75 | 8-19 | .296 | - | | Ted Grant Court · Syracuse, NY |
| 28 | Thu Feb 20 | vsSt Francis PA | L76-81 (OT) | 9-19 | .321 | - | | Ted Grant Court · Syracuse, NY |
