| 1 | Mon Nov 4 | at #7Duke | L62-96 | 0-1 | .000 | - | ACC Network | Cameron Indoor Stadium · Durham, NC |
| 2 | Wed Nov 6 | vs TBD | W98-47 | 1-1 | .500 | - | ESPN+ | Cross Insurance Center · Bangor, ME |
| 3 | Sun Nov 10 | at Brown | W69-67 | 2-1 | .667 | - | ESPN+ | Pizzitola Sports Center · Providence, RI |
| 4 | Fri Nov 15 | at Quinnipiac | L55-58 | 2-2 | .500 | - | ESPN+ | M&T Bank Arena · Hamden, CT |
| 5 | Wed Nov 20 | at Richmond | L66-70 | 2-3 | .400 | - | ESPN+ | Robins Center · Richmond, VA |
| 6 | Sun Nov 24 | vs Holy Cross | W80-55 | 3-3 | .500 | - | ESPN+ | Cross Insurance Center · Bangor, ME |
| 7 | Fri Nov 29 | at Elon | W69-56 | 4-3 | .571 | - | ESPN+ | Schar Center · Elon, NC |
| 8 | Sat Nov 30 | at Penn | L64-77 | 4-4 | .500 | - | ESPN+ | The Palestra · Philadelphia, PA |
| 9 | Sun Dec 1 | at Navy | W71-66 | 5-4 | .556 | - | ESPN+ | Alumni Hall (Navy) · Annapolis, MD |
| 10 | Tue Dec 3 | vsTBD | W103-51 | 6-4 | .600 | - | ESPN+ | Cross Insurance Center · Bangor, ME |
| 11 | Sun Dec 8 | at Fordham | L72-87 | 6-5 | .545 | - | ESPN+ | Rose Hill Gymnasium · Bronx, NY |
| 12 | Wed Dec 11 | at Duquesne | W61-56 | 7-5 | .583 | - | ESPN+ | UPMC Cooper Fieldhouse · Pittsburgh, PA |
| 13 | Sat Dec 14 | at Canisius | W84-79 | 8-5 | .615 | - | ESPN+ | Koessler Athletic Center · Buffalo, NY |
| 14 | Sat Dec 21 | at Stony Brook | L72-74 | 8-6 | .571 | - | | Island FCU Arena · Stony Brook, NY |
| 15 | Sun Dec 29 | vs Boston Univ | L56-59 | 8-7 | .533 | - | ESPN+ | Cross Insurance Center · Bangor, ME |
| 16 | Sat Jan 4 | at Bryant | L55-81 | 8-8 | .500 | - | ESPN+ | Chace Athletic Center · Smithfield, RI |
| 17 | Thu Jan 9 | vs Binghamton | W82-71 | 9-8 | .529 | - | ESPN+ | Cross Insurance Center · Bangor, ME |
| 18 | Sat Jan 11 | vs Albany | W87-66 | 10-8 | .556 | - | ESPN+ | Cross Insurance Center · Bangor, ME |
| 19 | Thu Jan 16 | at NJIT | W57-44 | 11-8 | .579 | - | ESPN+ | NJIT Wellness and Events Center · Newark, NJ |
| 20 | Sat Jan 18 | at UMBC | W87-62 | 12-8 | .600 | - | ESPN+ | Chesapeake Employers Insurance Arena · Baltimore, MD |
| 21 | Thu Jan 23 | at UMass Lowell | W86-85 (OT) | 13-8 | .619 | - | ESPN+ | Costello Athletic Center · Lowell, MA |
| 22 | Thu Jan 30 | vs New Hampshire | W71-46 | 14-8 | .636 | - | ESPN+ | Cross Insurance Center · Bangor, ME |
| 23 | Sat Feb 1 | at Vermont | L49-55 | 14-9 | .609 | - | ESPN+ | Patrick Gymnasium · Burlington, VT |
| 24 | Thu Feb 6 | vsNJIT | W78-74 | 15-9 | .625 | - | ESPN+ | Cross Insurance Center · Bangor, ME |
| 25 | Sat Feb 8 | vsUMBC | W73-50 | 16-9 | .640 | - | ESPN+ | Cross Insurance Center · Bangor, ME |
| 26 | Sat Feb 15 | vsVermont | L61-65 | 16-10 | .615 | - | ESPN+ | Cross Insurance Center · Bangor, ME |
| 27 | Thu Feb 20 | atAlbany | L68-79 | 16-11 | .593 | - | ESPN+ | SEFCU Arena · Albany, NY |
