| 1 | Mon Nov 4 | at UMass | L74-103 | 0-1 | .000 | - | ESPN+ | William D. Mullins Memorial Center · Amherst, MA |
| 2 | Wed Nov 6 | vs TBD | W99-69 | 1-1 | .500 | - | ESPN+ | Lundholm Gymnasium · Durham, NH |
| 3 | Sat Nov 9 | at #3UConn | L53-92 | 1-2 | .333 | - | FS2 | Gampel Pavilion · Storrs, CT |
| 4 | Tue Nov 12 | vs Fairfield | L56-62 | 1-3 | .250 | - | ESPN+ | Lundholm Gymnasium · Durham, NH |
| 5 | Fri Nov 15 | at Brown | L58-76 | 1-4 | .200 | - | ESPN+ | Pizzitola Sports Center · Providence, RI |
| 6 | Sat Nov 16 | at Sacred Heart | L63-80 | 1-5 | .167 | - | ESPN+ | William H. Pitt Center · Fairfield, CT |
| 7 | Sun Nov 17 | at Holy Cross | L72-74 | 1-6 | .143 | - | ESPN+ | Hart Center · Worcester, MA |
| 8 | Wed Nov 20 | vsTBD | W78-64 | 2-6 | .250 | - | ESPN+ | Lundholm Gymnasium · Durham, NH |
| 9 | Sat Nov 23 | at Marist | L49-54 | 2-7 | .222 | - | ESPN+ | McCann Arena · Poughkeepsie, NY |
| 10 | Mon Nov 25 | at Columbia | L57-83 | 2-8 | .200 | - | ESPN+ | Francis S. Levien Gymnasium · New York, NY |
| 11 | Sun Dec 1 | at Fordham | L61-83 | 2-9 | .182 | - | ESPN+ | Rose Hill Gymnasium · Bronx, NY |
| 12 | Tue Dec 3 | vs Dartmouth | L65-69 | 2-10 | .167 | - | ESPN+ | Lundholm Gymnasium · Durham, NH |
| 13 | Sun Dec 8 | vs Harvard | L62-72 | 2-11 | .154 | - | ESPN+ | Lundholm Gymnasium · Durham, NH |
| 14 | Sun Dec 22 | at Stonehill | L83-90 | 2-12 | .143 | - | | placeholder · sf, ca |
| 15 | Mon Dec 30 | at Iowa | L70-112 | 2-13 | .133 | - | BTN | Carver-Hawkeye Arena · Iowa City, IA |
| 16 | Sat Jan 4 | vs Vermont | L40-60 | 2-14 | .125 | - | ESPN+ | Lundholm Gymnasium · Durham, NH |
| 17 | Thu Jan 9 | vs Albany | L57-61 | 2-15 | .118 | - | ESPN+ | Lundholm Gymnasium · Durham, NH |
| 18 | Sat Jan 11 | vs Binghamton | W79-72 | 3-15 | .167 | - | ESPN+ | Lundholm Gymnasium · Durham, NH |
| 19 | Thu Jan 16 | at UMBC | W79-76 | 4-15 | .211 | - | ESPN+ | Chesapeake Employers Insurance Arena · Baltimore, MD |
| 20 | Sat Jan 18 | at NJIT | L59-64 | 4-16 | .200 | - | ESPN+ | NJIT Wellness and Events Center · Newark, NJ |
| 21 | Thu Jan 23 | vs Bryant | L76-95 | 4-17 | .190 | - | ESPN+ | Lundholm Gymnasium · Durham, NH |
| 22 | Sat Jan 25 | at UMass Lowell | L80-97 | 4-18 | .182 | - | ESPN+ | Costello Athletic Center · Lowell, MA |
| 23 | Thu Jan 30 | at Maine | L46-71 | 4-19 | .174 | - | ESPN+ | Cross Insurance Center · Bangor, ME |
| 24 | Thu Feb 6 | vsUMBC | W79-78 | 5-19 | .208 | - | ESPN+ | Lundholm Gymnasium · Durham, NH |
| 25 | Sat Feb 8 | vsNJIT | W80-69 | 6-19 | .240 | - | ESPN+ | Lundholm Gymnasium · Durham, NH |
| 26 | Thu Feb 13 | atVermont | L59-79 | 6-20 | .231 | - | ESPN+ | Patrick Gymnasium · Burlington, VT |
| 27 | Sat Feb 15 | vsUMass Lowell | W80-79 | 7-20 | .259 | - | ESPN+ | Lundholm Gymnasium · Durham, NH |
| 28 | Thu Feb 20 | atBinghamton | L60-79 | 7-21 | .250 | - | ESPN+ | Events Center (Binghamton) · Binghamton, NY |
