| 1 | Mon Nov 4 | vs TBD | W129-47 | 1-0 | 1.000 | - | ESPN+ | Edward Leede Arena · Hanover, NH |
| 2 | Sat Nov 9 | vs Sacred Heart | W81-76 | 2-0 | 1.000 | - | ESPN+ | Edward Leede Arena · Hanover, NH |
| 3 | Wed Nov 13 | vs Albany | L73-87 | 2-1 | .667 | - | ESPN+ | Edward Leede Arena · Hanover, NH |
| 4 | Sat Nov 16 | at Boston Univ | L50-78 | 2-2 | .500 | - | ESPN+ | Case Gym · Boston, MA |
| 5 | Tue Nov 19 | at Marist | L62-75 | 2-3 | .400 | - | ESPN+ | McCann Arena · Poughkeepsie, NY |
| 6 | Fri Nov 29 | at Boston College | W88-83 | 3-3 | .500 | - | ESPN+ | Silvio O. Conte Forum · Chestnut Hill, MA |
| 7 | Tue Dec 3 | at New Hampshire | W69-65 | 4-3 | .571 | - | ESPN+ | Lundholm Gymnasium · Durham, NH |
| 8 | Sun Dec 8 | at UIC | L68-69 (OT) | 4-4 | .500 | - | ESPN+ | Credit Union 1 Arena · Chicago, IL |
| 9 | Wed Dec 11 | at Notre Dame | L65-77 | 4-5 | .444 | - | ESPN+ | Purcell Pavilion · South Bend, IN |
| 10 | Sat Dec 14 | at UMass Lowell | L83-92 | 4-6 | .400 | - | ESPN+ | Costello Athletic Center · Lowell, MA |
| 11 | Wed Dec 18 | vs Le Moyne | L76-80 | 4-7 | .364 | - | ESPN+ | Edward Leede Arena · Hanover, NH |
| 12 | Sat Dec 21 | vs Vermont | W84-54 | 5-7 | .417 | - | ESPN+ | Edward Leede Arena · Hanover, NH |
| 13 | Wed Jan 1 | vsTBD | W108-55 | 6-7 | .462 | - | ESPN+ | Edward Leede Arena · Hanover, NH |
| 14 | Sat Jan 11 | vs Penn | W73-70 | 7-7 | .500 | - | ESPN+ | Edward Leede Arena · Hanover, NH |
| 15 | Sat Jan 18 | vs Princeton | L80-81 | 7-8 | .467 | - | ESPN+ | Edward Leede Arena · Hanover, NH |
| 16 | Mon Jan 20 | at Yale | L67-83 | 7-9 | .438 | - | ESPN+ | John J. Lee Amphitheater · New Haven, CT |
| 17 | Sat Jan 25 | at Brown | W84-83 | 8-9 | .471 | - | ESPN+ | Pizzitola Sports Center · Providence, RI |
| 18 | Fri Jan 31 | at Cornell | L64-76 | 8-10 | .444 | - | ESPN+ | Newman Arena · Ithaca, NY |
| 19 | Sat Feb 1 | at Columbia | W95-89 | 9-10 | .474 | - | ESPN+ | Francis S. Levien Gymnasium · New York, NY |
| 20 | Sat Feb 8 | vs Harvard | W76-56 | 10-10 | .500 | - | ESPN+ | Edward Leede Arena · Hanover, NH |
| 21 | Fri Feb 14 | vsColumbia | W78-56 | 11-10 | .524 | - | ESPN+ | Edward Leede Arena · Hanover, NH |
| 22 | Sat Feb 15 | vsCornell | W88-49 | 12-10 | .545 | - | ESPN+ | Edward Leede Arena · Hanover, NH |
