| 1 | Tue Nov 9 | at Boston College | L57-73 | 0-1 | .000 | - | | Silvio O. Conte Forum · Chestnut Hill, MA |
| 2 | Sat Nov 13 | atGeorgetown | W69-60 | 1-1 | .500 | - | FS2 | Capital One Arena · Washington, D.C. |
| 3 | Tue Nov 16 | vsTBD | W114-74 | 2-1 | .667 | - | | Edward Leede Arena · Hanover, NH |
| 4 | Sun Nov 28 | atBryant | W63-61 (OT) | 3-1 | .750 | - | | Chace Athletic Center · Smithfield, RI |
| 5 | Wed Dec 1 | atVermont | L65-83 | 3-2 | .600 | - | | Patrick Gymnasium · Burlington, VT |
| 6 | Sat Dec 4 | atFGCU | L68-78 (OT) | 3-3 | .500 | - | | Alico Arena · Fort Myers, FL |
| 7 | Wed Dec 8 | vsQuinnipiac | L69-72 | 3-4 | .429 | - | | Edward Leede Arena · Hanover, NH |
| 8 | Sat Dec 11 | vsBoston Univ | L62-65 | 3-5 | .375 | - | | Edward Leede Arena · Hanover, NH |
| 9 | Thu Dec 16 | atStanford | L78-89 (OT) | 3-6 | .333 | - | PACN | Maples Pavilion · Stanford, CA |
| 10 | Sun Dec 19 | atCalifornia | L55-61 | 3-7 | .300 | - | PACN | Haas Pavilion · Berkeley, CA |
| 11 | Tue Dec 21 | atBakersfield | L57-61 | 3-8 | .273 | - | | Icardo Center · Bakersfield, CA |
| 13 | Sun Jan 2 | atCornell | L71-79 | 3-9 | .250 | - | | Newman Arena · Ithaca, NY |
| 14 | Fri Jan 7 | vsYale | PPD | 9-16 | .360 | - | | Edward Leede Arena · Hanover, NH |
| 15 | Sat Jan 8 | vsBrown | W58-46 | 4-9 | .308 | - | | Edward Leede Arena · Hanover, NH |
| 16 | Sat Jan 15 | atPenn | L68-78 | 4-10 | .286 | - | | The Palestra · Philadelphia, PA |
| 17 | Mon Jan 17 | vsHarvard | L59-60 | 4-11 | .267 | - | | Edward Leede Arena · Hanover, NH |
| 18 | Sat Jan 22 | vsPrinceton | L80-84 | 4-12 | .250 | - | | Edward Leede Arena · Hanover, NH |
| 19 | Sat Jan 29 | atColumbia | W76-63 | 5-12 | .294 | - | | Francis S. Levien Gymnasium · New York, NY |
| 20 | Fri Feb 4 | atYale | L69-72 | 5-13 | .278 | - | ESPNU | John J. Lee Amphitheater · New Haven, CT |
| 21 | Sat Feb 5 | atBrown | L60-62 | 5-14 | .263 | - | | Pizzitola Sports Center · Providence, RI |
| 22 | Sat Feb 12 | atPrinceton | L40-85 | 5-15 | .250 | - | | Jadwin Gymnasium · Princeton, NJ |
| 23 | Fri Feb 18 | vsCornell | W71-59 | 6-15 | .286 | - | | Edward Leede Arena · Hanover, NH |
| 24 | Sat Feb 19 | vsColumbia | W79-50 | 7-15 | .318 | - | | Edward Leede Arena · Hanover, NH |
| 25 | Tue Feb 22 | vsYale | L61-66 | 7-16 | .304 | - | | Edward Leede Arena · Hanover, NH |
| 26 | Sat Feb 26 | vsPenn | W84-70 | 8-16 | .333 | - | | Edward Leede Arena · Hanover, NH |
| 27 | Sat Mar 5 | atHarvard | W76-54 | 9-16 | .360 | - | | Lavietes Pavilion · Cambridge, MA |
