| 1 | Wed Nov 6 | vs Merrimack | W84-64 | 1-0 | 1.000 | - | | Cross Insurance Center · Bangor, ME |
| 2 | Sun Nov 10 | at Harvard | L46-67 | 1-1 | .500 | - | | Lavietes Pavilion · Cambridge, MA |
| 3 | Sat Nov 16 | at Portland | L62-71 | 1-2 | .333 | - | | Chiles Center · Portland, OR |
| 4 | Tue Nov 19 | at #25Washington | L53-72 | 1-3 | .250 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 5 | Sun Nov 24 | vs TBD | W90-50 | 2-3 | .400 | - | | Cross Insurance Center · Bangor, ME |
| 6 | Wed Nov 27 | at #7Virginia | L26-46 | 2-4 | .333 | - | ACC Network | John Paul Jones Arena · Charlottesville, VA |
| 7 | Sun Dec 1 | at UConn | L40-64 | 2-5 | .286 | - | | Gampel Pavilion · Storrs, CT |
| 8 | Wed Dec 4 | at Northeastern | L63-78 | 2-6 | .250 | - | | Matthews Arena · Boston, MA |
| 9 | Sat Dec 7 | at C Connecticut | W66-64 | 3-6 | .333 | - | | William H. Detrick Gymnasium · New Britain, CT |
| 10 | Wed Dec 11 | vs Dartmouth | L44-77 | 3-7 | .300 | - | | Cross Insurance Center · Bangor, ME |
| 11 | Sun Dec 15 | vs Quinnipiac | L61-81 | 3-8 | .273 | - | | Cross Insurance Center · Bangor, ME |
| 12 | Fri Dec 20 | at UMass | L53-74 | 3-9 | .250 | - | | William D. Mullins Memorial Center · Amherst, MA |
| 13 | Sun Dec 29 | at Hawai'i | L51-91 | 3-10 | .231 | - | | Stan Sheriff Center · Honolulu, HI |
| 14 | Thu Jan 2 | vs Columbia | W75-72 (OT) | 4-10 | .286 | - | | Cross Insurance Center · Bangor, ME |
| 15 | Sun Jan 5 | vs Stony Brook | L52-73 | 4-11 | .267 | - | | Cross Insurance Center · Bangor, ME |
| 16 | Wed Jan 8 | at New Hampshire | L51-57 | 4-12 | .250 | - | | Lundholm Gymnasium · Durham, NH |
| 17 | Sat Jan 11 | at Albany | L70-76 | 4-13 | .235 | - | | SEFCU Arena · Albany, NY |
| 18 | Wed Jan 15 | vs UMass Lowell | W104-98 (OT) | 5-13 | .278 | - | | Cross Insurance Center · Bangor, ME |
| 19 | Sun Jan 19 | vs Binghamton | W86-63 | 6-13 | .316 | - | | Cross Insurance Center · Bangor, ME |
| 20 | Wed Jan 22 | vs Vermont | L57-59 | 6-14 | .300 | - | | Cross Insurance Center · Bangor, ME |
| 21 | Sat Jan 25 | at UMBC | L53-63 | 6-15 | .286 | - | | Chesapeake Employers Insurance Arena · Baltimore, MD |
| 22 | Sat Feb 1 | vsTBD | L49-55 | 6-16 | .273 | - | | Cross Insurance Center · Bangor, ME |
| 23 | Wed Feb 5 | atVermont | L52-77 | 6-17 | .261 | - | | Patrick Gymnasium · Burlington, VT |
| 24 | Sat Feb 8 | atBinghamton | W82-75 | 7-17 | .292 | - | | Events Center (Binghamton) · Binghamton, NY |
| 25 | Wed Feb 12 | atUMass Lowell | L63-71 | 7-18 | .280 | - | | Costello Athletic Center · Lowell, MA |
| 26 | Sun Feb 16 | vsAlbany | L60-66 | 7-19 | .269 | - | | Cross Insurance Center · Bangor, ME |
| 27 | Sat Feb 22 | atStony Brook | L46-54 | 7-20 | .259 | - | | Island FCU Arena · Stony Brook, NY |
| 28 | Wed Feb 26 | vsNew Hampshire | L70-77 | 7-21 | .250 | - | | Cross Insurance Center · Bangor, ME |
| 29 | Sat Feb 29 | vsUMBC | W74-48 | 8-21 | .276 | - | | Cross Insurance Center · Bangor, ME |
| 30 | Tue Mar 3 | atTBD | W71-65 | 9-21 | .300 | - | | Chase Arena |
| 31 | Sat Mar 7 | atVermont | L50-61 | 9-22 | .290 | - | | Patrick Gymnasium · Burlington, VT |
