| 1 | Mon Nov 3 | vs TBD | W120-83 | 1-0 | 1.000 | - | ESPN+ | Chiles Center · Portland, OR |
| 2 | Thu Nov 6 | vsAR-Pine Bluff | W83-74 | 2-0 | 1.000 | - | ESPN+ | Chiles Center · Portland, OR |
| 3 | Sun Nov 9 | vsUC Davis | W67-63 | 3-0 | 1.000 | - | ESPN+ | Chiles Center · Portland, OR |
| 4 | Sat Nov 15 | atWyoming | L56-93 | 3-1 | .750 | - | | Arena Auditorium · Laramie, WY |
| 5 | Fri Nov 21 | vsFullerton | W103-85 | 4-1 | .800 | - | ESPN+ | Chiles Center · Portland, OR |
| 6 | Sat Nov 22 | vsN Colorado | L80-86 (OT) | 4-2 | .667 | - | ESPN+ | Chiles Center · Portland, OR |
| 7 | Sun Nov 23 | vsSt Thomas (MN) | L66-76 | 4-3 | .571 | - | ESPN+ | Chiles Center · Portland, OR |
| 8 | Wed Nov 26 | vsLong Beach St | W93-73 | 5-3 | .625 | - | ESPN+ | Chiles Center · Portland, OR |
| 9 | Mon Dec 1 | atStanford | L72-94 | 5-4 | .556 | - | ACC Extra | Maples Pavilion · Stanford, CA |
| 10 | Fri Dec 5 | vsTBD | W104-87 | 6-4 | .600 | - | | Chiles Center · Portland, OR |
| 11 | Sun Dec 14 | vsKent State | W88-78 | 7-4 | .636 | - | ESPN+ | Chiles Center · Portland, OR |
| 12 | Wed Dec 17 | atOregon | L69-94 | 7-5 | .583 | - | BTN | Matthew Knight Arena · Eugene, OR |
| 13 | Mon Dec 22 | atUCSB | L61-79 | 7-6 | .538 | - | ESPN+ | The Thunderdome · Santa Barbara, CA |
| 14 | Sun Dec 28 | vsWashington St | L62-67 | 7-7 | .500 | - | ESPN+ | Chiles Center · Portland, OR |
| 15 | Tue Dec 30 | vsSanta Clara | L85-92 | 7-8 | .467 | - | ESPN+ | Chiles Center · Portland, OR |
| 16 | Fri Jan 2 | atSaint Mary's | L57-78 | 7-9 | .438 | - | ESPN+ | University Credit Union Pavilion · Moraga, CA |
| 17 | Sun Jan 4 | atSan Francisco | L68-73 | 7-10 | .412 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
| 18 | Thu Jan 8 | vsPacific | W90-89 (OT) | 8-10 | .444 | - | ESPN+ | Chiles Center · Portland, OR |
| 19 | Sat Jan 10 | vsOregon St | W82-76 | 9-10 | .474 | - | ESPN+ | Chiles Center · Portland, OR |
| 20 | Wed Jan 14 | atPepperdine | L63-67 | 9-11 | .450 | - | ESPN+ | Firestone Fieldhouse · Malibu, CA |
| 21 | Sat Jan 17 | atLMU | W71-58 | 10-11 | .476 | - | ESPN+ | Gersten Pavilion · Los Angeles, CA |
| 22 | Sat Jan 24 | vsSaint Mary's | L69-75 | 10-12 | .455 | - | ESPN+ | Chiles Center · Portland, OR |
| 23 | Wed Jan 28 | atPacific | L51-74 | 10-13 | .435 | - | ESPN+ | Alex G. Spanos Center · Stockton, CA |
| 24 | Sat Jan 31 | atWashington St | L74-104 | 10-14 | .417 | - | ESPN+ | Friel Court at Beasley Coliseum · Pullman, WA |
| 25 | Wed Feb 4 | vs6Gonzaga | W87-80 | 11-14 | .440 | - | ESPN+ | Chiles Center · Portland, OR |
| 26 | Sat Feb 7 | vsSeattle U | W54-53 | 12-14 | .462 | - | ESPN+ | Chiles Center · Portland, OR |
| 27 | Wed Feb 11 | atSan Diego | L58-71 | 12-15 | .444 | - | ESPN+ | Jenny Craig Pavilion · San Diego, CA |
| 28 | Wed Feb 18 | vsPepperdine | L87-95 | 12-16 | .429 | - | ESPN+ | Chiles Center · Portland, OR |
| 29 | Sat Feb 21 | atSeattle U | L59-71 | 12-17 | .414 | - | ESPN+ | Redhawk Center · Seattle, WA |
| 30 | Wed Feb 25 | at9Gonzaga | L48-89 | 12-18 | .400 | - | ESPN+ | McCarthey Athletic Center · Spokane, WA |
| 31 | Sat Feb 28 | vsSan Diego | W87-74 | 13-18 | .419 | - | ESPN+ | Chiles Center · Portland, OR |
