| 1 | Wed Nov 6 | vs TBD | W83-70 | 1-0 | 1.000 | - | ESPN+ | Chiles Center · Portland, OR |
| 2 | Sat Nov 9 | vs UCSB | L53-94 | 1-1 | .500 | - | ESPN+ | Chiles Center · Portland, OR |
| 3 | Tue Nov 12 | at Oregon | L70-80 (OT) | 1-2 | .333 | - | BTN | Matthew Knight Arena · Eugene, OR |
| 4 | Sat Nov 16 | at Long Beach St | W63-61 | 2-2 | .500 | - | ESPN+ | Walter Pyramid · Long Beach, CA |
| 5 | Thu Nov 21 | vs South Florida | L68-74 | 2-3 | .400 | - | ESPN2 | Chiles Center · Portland, OR |
| 6 | Fri Nov 22 | vs Ohio | L73-85 | 2-4 | .333 | - | ESPNU | Chiles Center · Portland, OR |
| 7 | Sun Nov 24 | at Princeton | L67-94 | 2-5 | .286 | - | ESPNU | Jadwin Gymnasium · Princeton, NJ |
| 8 | Sun Dec 1 | vs Denver | W101-90 (2OT) | 3-5 | .375 | - | ESPN+ | Chiles Center · Portland, OR |
| 9 | Fri Dec 6 | at Kent State | L57-76 | 3-6 | .333 | - | ESPN+ | M.A.C. Center · Kent, OH |
| 10 | Tue Dec 10 | vs Kansas City | L64-69 | 3-7 | .300 | - | ESPN+ | Chiles Center · Portland, OR |
| 11 | Mon Dec 16 | vsTBD | W100-69 | 4-7 | .364 | - | ESPN+ | Chiles Center · Portland, OR |
| 12 | Wed Dec 18 | vs Bakersfield | L64-81 | 4-8 | .333 | - | ESPN+ | Chiles Center · Portland, OR |
| 13 | Sat Dec 21 | vs Lafayette | W74-64 | 5-8 | .385 | - | ESPN+ | Chiles Center · Portland, OR |
| 14 | Sat Dec 28 | vs Washington St | L73-89 | 5-9 | .357 | - | ESPN+ | Chiles Center · Portland, OR |
| 15 | Mon Dec 30 | at Oregon St | L79-89 | 5-10 | .333 | - | ESPN+ | Gill Coliseum · Corvallis, OR |
| 16 | Thu Jan 2 | at #19Gonzaga | L50-81 | 5-11 | .313 | - | ESPN+ | McCarthey Athletic Center · Spokane, WA |
| 17 | Sat Jan 4 | vs Saint Mary's | L58-81 | 5-12 | .294 | - | ESPN+ | Chiles Center · Portland, OR |
| 18 | Thu Jan 9 | at San Francisco | L72-81 | 5-13 | .278 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
| 19 | Thu Jan 16 | vs Pacific | W84-81 (OT) | 6-13 | .316 | - | ESPN+ | Chiles Center · Portland, OR |
| 20 | Sat Jan 18 | atWashington St | L70-92 | 6-14 | .300 | - | ESPN+ | Friel Court at Beasley Coliseum · Pullman, WA |
| 21 | Thu Jan 23 | vs San Diego | W92-82 | 7-14 | .333 | - | ESPN+ | Chiles Center · Portland, OR |
| 22 | Sat Jan 25 | vsGonzaga | L62-105 | 7-15 | .318 | - | ESPN+ | Chiles Center · Portland, OR |
| 23 | Thu Jan 30 | at LMU | L63-88 | 7-16 | .304 | - | ESPN+ | Gersten Pavilion · Los Angeles, CA |
| 24 | Sat Feb 1 | at Pepperdine | W84-64 | 8-16 | .333 | - | ESPN+ | Firestone Fieldhouse · Malibu, CA |
| 25 | Thu Feb 6 | vs Santa Clara | L50-97 | 8-17 | .320 | - | ESPN+ | Chiles Center · Portland, OR |
| 26 | Thu Feb 13 | vsOregon St | W84-72 | 9-17 | .346 | - | ESPN+ | Chiles Center · Portland, OR |
| 27 | Sat Feb 15 | vsLMU | W89-78 | 10-17 | .370 | - | ESPN+ | Chiles Center · Portland, OR |
| 28 | Wed Feb 19 | atSaint Mary's | L66-79 | 10-18 | .357 | - | ESPN+ | University Credit Union Pavilion · Moraga, CA |
