| 1 | Mon Nov 4 | vs TBD | W108-85 | 1-0 | 1.000 | - | | Arena Auditorium · Laramie, WY |
| 2 | Sun Nov 10 | vs Tennessee St | W81-66 | 2-0 | 1.000 | - | | Arena Auditorium · Laramie, WY |
| 3 | Wed Nov 13 | at Texas Tech | L49-96 | 2-1 | .667 | - | ESPN+ | United Supermarkets Arena · Lubbock, TX |
| 4 | Sat Nov 16 | vs Utah Tech | W86-69 | 3-1 | .750 | - | | Arena Auditorium · Laramie, WY |
| 5 | Fri Nov 22 | vs SE Louisiana | W64-61 | 4-1 | .800 | - | | Arena Auditorium · Laramie, WY |
| 6 | Tue Nov 26 | at Tulane | W64-63 | 5-1 | .833 | - | CBS | Devlin Fieldhouse · New Orleans, LA |
| 7 | Wed Nov 27 | at LMU | L70-73 | 5-2 | .714 | - | | Gersten Pavilion · Los Angeles, CA |
| 8 | Wed Dec 4 | at Utah State | L67-70 | 5-3 | .625 | - | | Dee Glen Smith Spectrum · Logan, UT |
| 9 | Tue Dec 10 | at South Dakota | L81-82 | 5-4 | .556 | - | | Sanford Coyote Sports Center · Vermillion, SD |
| 10 | Sat Dec 14 | at BYU | L49-68 | 5-5 | .500 | - | ESPN+ | Marriott Center · Provo, UT |
| 11 | Thu Dec 19 | vs Bellarmine | W92-55 | 6-5 | .545 | - | | Arena Auditorium · Laramie, WY |
| 12 | Sun Dec 22 | at Fullerton | W73-69 | 7-5 | .583 | - | ESPN+ | Titan Gym · Fullerton, CA |
| 13 | Sat Dec 28 | vs Nevada | W66-63 | 8-5 | .615 | - | | Arena Auditorium · Laramie, WY |
| 14 | Tue Dec 31 | vs Boise St | L58-67 | 8-6 | .571 | - | | Arena Auditorium · Laramie, WY |
| 15 | Sat Jan 4 | at Air Force | W70-65 | 9-6 | .600 | - | | Clune Arena · Colorado Springs, CO |
| 16 | Tue Jan 7 | vs New Mexico | L53-61 | 9-7 | .563 | - | CBS | Arena Auditorium · Laramie, WY |
| 17 | Tue Jan 14 | atBoise St | L55-96 | 9-8 | .529 | - | | ExtraMile Arena · Boise, ID |
| 18 | Sat Jan 18 | vs Colorado St | L63-79 | 9-9 | .500 | - | | Arena Auditorium · Laramie, WY |
| 19 | Tue Jan 21 | at UNLV | W63-61 | 10-9 | .526 | - | CBS | Thomas & Mack Center · Las Vegas, NV |
| 20 | Sat Jan 25 | at San Jose St | L58-67 | 10-10 | .500 | - | | Provident Credit Union Event Center · San Jose, CA |
| 21 | Tue Jan 28 | vs Fresno St | W83-72 (OT) | 11-10 | .524 | - | | Arena Auditorium · Laramie, WY |
| 22 | Sat Feb 1 | at SDSU | L61-63 | 11-11 | .500 | - | CBS | Viejas Arena · San Diego, CA |
| 23 | Tue Feb 4 | vsUtah State | L67-71 | 11-12 | .478 | - | | Arena Auditorium · Laramie, WY |
| 24 | Sat Feb 8 | vsUNLV | L57-68 | 11-13 | .458 | - | | Arena Auditorium · Laramie, WY |
| 25 | Wed Feb 12 | atNew Mexico | L67-71 | 11-14 | .440 | - | FS1 | The Pit · Albuquerque, NM |
| 26 | Sat Feb 15 | atColorado St | L53-88 | 11-15 | .423 | - | | Moby Arena · Fort Collins, CO |
| 27 | Tue Feb 18 | vsAir Force | W69-62 | 12-15 | .444 | - | | Arena Auditorium · Laramie, WY |
| 28 | Sat Feb 22 | vsSan Jose St | L73-82 | 12-16 | .429 | - | | Arena Auditorium · Laramie, WY |
| 29 | Tue Feb 25 | atNevada | L61-84 | 12-17 | .414 | - | | Lawlor Events Center · Reno, NV |
| 30 | Sat Mar 1 | vsSDSU | L69-72 | 12-18 | .400 | - | CBS | Arena Auditorium · Laramie, WY |
| 31 | Tue Mar 4 | atFresno St | L58-62 | 12-19 | .387 | - | | Save Mart Center · Fresno, CA |
| 32 | Wed Mar 12 | atSan Jose St | L61-66 | 12-20 | .375 | - | | Provident Credit Union Event Center · San Jose, CA |
