| 1 | Tue Nov 5 | vs Idaho St | W54-40 | 1-0 | 1.000 | - | | Arena Auditorium · Laramie, WY |
| 2 | Sun Nov 10 | at South Carolina | L32-66 | 1-1 | .500 | - | SEC Network | Colonial Life Arena · Columbia, SC |
| 3 | Wed Nov 13 | vs Fullerton | L53-60 | 1-2 | .333 | - | | Arena Auditorium · Laramie, WY |
| 4 | Sat Nov 16 | vs Oregon St | L63-83 | 1-3 | .250 | - | | Arena Auditorium · Laramie, WY |
| 5 | Tue Nov 19 | vs Detroit Mercy | W76-49 | 2-3 | .400 | - | | Arena Auditorium · Laramie, WY |
| 6 | Thu Nov 21 | vs Louisiana | W69-61 (OT) | 3-3 | .500 | - | | Arena Auditorium · Laramie, WY |
| 7 | Sun Nov 24 | at Colorado | L41-56 | 3-4 | .429 | - | | CU Events Center · Boulder, CO |
| 8 | Tue Nov 26 | vs TCU | L47-64 | 3-5 | .375 | - | | Arena Auditorium · Laramie, WY |
| 9 | Wed Dec 4 | vs Air Force | L77-86 | 3-6 | .333 | - | | Arena Auditorium · Laramie, WY |
| 10 | Sat Dec 7 | vs New Mexico | L65-79 | 3-7 | .300 | - | | Arena Auditorium · Laramie, WY |
| 11 | Sat Dec 14 | vs N Colorado | L53-74 | 3-8 | .273 | - | | Arena Auditorium · Laramie, WY |
| 12 | Wed Dec 18 | vs Utah Valley | L67-69 | 3-9 | .250 | - | | Arena Auditorium · Laramie, WY |
| 13 | Sat Dec 21 | at Denver | W72-66 (OT) | 4-9 | .308 | - | | Hamilton Gymnasium · Denver, CO |
| 14 | Sat Dec 28 | vs TBD | W82-68 | 5-9 | .357 | - | | Arena Auditorium · Laramie, WY |
| 15 | Wed Jan 1 | at Boise St | L54-65 | 5-10 | .333 | - | | ExtraMile Arena · Boise, ID |
| 16 | Sat Jan 4 | at Colorado St | L61-72 | 5-11 | .313 | - | | Moby Arena · Fort Collins, CO |
| 17 | Wed Jan 8 | vs #7SDSU | L52-72 | 5-12 | .294 | - | | Arena Auditorium · Laramie, WY |
| 18 | Sat Jan 11 | vs UNLV | L69-78 (OT) | 5-13 | .278 | - | | Arena Auditorium · Laramie, WY |
| 19 | Tue Jan 14 | at Nevada | L67-68 | 5-14 | .263 | - | CBS | Lawlor Events Center · Reno, NV |
| 20 | Sat Jan 18 | vs Fresno St | L50-65 | 5-15 | .250 | - | | Arena Auditorium · Laramie, WY |
| 21 | Tue Jan 21 | at#4SDSU | L55-72 | 5-16 | .238 | - | CBS | Viejas Arena · San Diego, CA |
| 22 | Tue Jan 28 | vs Utah State | L45-68 | 5-17 | .227 | - | ESPNU | Arena Auditorium · Laramie, WY |
| 23 | Sat Feb 1 | at San Jose St | W71-66 | 6-17 | .261 | - | | Provident Credit Union Event Center · San Jose, CA |
| 24 | Tue Feb 4 | vsBoise St | L62-67 | 6-18 | .250 | - | | Arena Auditorium · Laramie, WY |
| 25 | Sat Feb 8 | atNew Mexico | L68-97 | 6-19 | .240 | - | | The Pit · Albuquerque, NM |
| 26 | Sat Feb 15 | vsColorado St | L70-77 | 6-20 | .231 | - | | Arena Auditorium · Laramie, WY |
| 27 | Wed Feb 19 | atUtah State | L58-78 | 6-21 | .222 | - | | Dee Glen Smith Spectrum · Logan, UT |
| 28 | Sat Feb 22 | atAir Force | W78-72 | 7-21 | .250 | - | | Clune Arena · Colorado Springs, CO |
| 29 | Tue Feb 25 | vsNevada | L68-73 | 7-22 | .241 | - | | Arena Auditorium · Laramie, WY |
| 30 | Sat Feb 29 | atFresno St | L55-63 | 7-23 | .233 | - | | Save Mart Center · Fresno, CA |
| 31 | Wed Mar 4 | atColorado St | W80-74 | 8-23 | .258 | - | | Moby Arena · Fort Collins, CO |
| 32 | Thu Mar 5 | atNevada | W74-71 | 9-23 | .281 | - | CBS | Lawlor Events Center · Reno, NV |
| 33 | Fri Mar 6 | atUtah State | L82-89 | 9-24 | .273 | - | CBS | Dee Glen Smith Spectrum · Logan, UT |
