| 1 | Mon Nov 3 | vs Incarnate Word | W98-64 | 1-0 | 1.000 | - | | Moby Arena · Fort Collins, CO |
| 2 | Sun Nov 9 | vsOmaha | W97-74 | 2-0 | 1.000 | - | | Moby Arena · Fort Collins, CO |
| 3 | Wed Nov 12 | vsCal Poly | W93-79 | 3-0 | 1.000 | - | | Moby Arena · Fort Collins, CO |
| 4 | Sun Nov 16 | atLoyola Chicago | W80-67 | 4-0 | 1.000 | - | ESPN+ | Joseph J. Gentile Arena · Chicago, IL |
| 5 | Fri Nov 21 | vsDenver | L81-83 | 4-1 | .800 | - | | Moby Arena · Fort Collins, CO |
| 6 | Wed Nov 26 | vsVirginia Tech | L64-66 | 4-2 | .667 | - | ESPNU | Moby Arena · Fort Collins, CO |
| 7 | Thu Nov 27 | vsWichita St | W76-70 | 5-2 | .714 | - | ESPNU | Moby Arena · Fort Collins, CO |
| 8 | Fri Nov 28 | atSouth Florida | W83-68 | 6-2 | .750 | - | ESPNU | Yuengling Center · Tampa, FL |
| 9 | Sat Dec 6 | vsColorado | W91-86 | 7-2 | .778 | - | CBSSN | Moby Arena · Fort Collins, CO |
| 10 | Tue Dec 9 | vsDartmouth | W76-55 | 8-2 | .800 | - | | Moby Arena · Fort Collins, CO |
| 11 | Sun Dec 14 | vsTBD | W104-54 | 9-2 | .818 | - | | Moby Arena · Fort Collins, CO |
| 12 | Sat Dec 20 | atUtah State | L58-100 | 9-3 | .750 | - | CBSSN | Dee Glen Smith Spectrum · Logan, UT |
| 13 | Tue Dec 30 | vsNevada | L62-75 | 9-4 | .692 | - | | Moby Arena · Fort Collins, CO |
| 14 | Sat Jan 3 | atGrand Canyon | W70-60 | 10-4 | .714 | - | | GCU Arena · Phoenix, AZ |
| 15 | Tue Jan 6 | vsNew Mexico | L70-80 | 10-5 | .667 | - | | Moby Arena · Fort Collins, CO |
| 16 | Fri Jan 9 | vsUNLV | W70-62 | 11-5 | .688 | - | CBSSN | Moby Arena · Fort Collins, CO |
| 17 | Tue Jan 13 | atFresno St | L69-79 | 11-6 | .647 | - | | Save Mart Center · Fresno, CA |
| 18 | Fri Jan 16 | atBoise St | L73-79 | 11-7 | .611 | - | FS1 | ExtraMile Arena · Boise, ID |
| 19 | Tue Jan 20 | vsAir Force | W81-52 | 12-7 | .632 | - | | Moby Arena · Fort Collins, CO |
| 20 | Fri Jan 23 | vsUtah State | L61-65 | 12-8 | .600 | - | FS1 | Moby Arena · Fort Collins, CO |
| 21 | Wed Jan 28 | atSDSU | L50-73 | 12-9 | .571 | - | FS1 | Viejas Arena · San Diego, CA |
| 22 | Sat Jan 31 | atWyoming | L57-68 | 12-10 | .545 | - | FS1 | Arena Auditorium · Laramie, WY |
| 23 | Sat Feb 7 | vsSan Jose St | W65-57 | 13-10 | .565 | - | | Moby Arena · Fort Collins, CO |
| 24 | Tue Feb 10 | atAir Force | W91-74 | 14-10 | .583 | - | | Clune Arena · Colorado Springs, CO |
| 25 | Sat Feb 14 | vsWyoming | W79-68 | 15-10 | .600 | - | | Moby Arena · Fort Collins, CO |
| 26 | Wed Feb 18 | atUNLV | W91-86 | 16-10 | .615 | - | CBSSN | Thomas & Mack Center · Las Vegas, NV |
| 27 | Sat Feb 21 | vsSDSU | W83-74 | 17-10 | .630 | - | CBSSN | Moby Arena · Fort Collins, CO |
| 28 | Tue Feb 24 | vsFresno St | W74-70 | 18-10 | .643 | - | | Moby Arena · Fort Collins, CO |
| 29 | Sat Feb 28 | atSan Jose St | W85-73 | 19-10 | .655 | - | | Provident Credit Union Event Center · San Jose, CA |
