| 1 | Tue Nov 9 | vs Oral Roberts | W109-80 | 1-0 | 1.000 | - | | Moby Arena · Fort Collins, CO |
| 2 | Fri Nov 12 | vsAR-Pine Bluff | W91-71 | 2-0 | 1.000 | - | | Moby Arena · Fort Collins, CO |
| 3 | Sun Nov 14 | vsTBD | W88-62 | 3-0 | 1.000 | - | | Moby Arena · Fort Collins, CO |
| 4 | Fri Nov 19 | vsBradley | W66-60 | 4-0 | 1.000 | - | | Moby Arena · Fort Collins, CO |
| 5 | Sun Nov 21 | atCreighton | W95-81 | 5-0 | 1.000 | - | | CHI Health Center Omaha · Omaha, NE |
| 6 | Mon Nov 22 | atNortheastern | W71-61 | 6-0 | 1.000 | - | | Matthews Arena · Boston, MA |
| 7 | Sat Nov 27 | vsN Colorado | W88-79 | 7-0 | 1.000 | - | | Moby Arena · Fort Collins, CO |
| 8 | Wed Dec 1 | vsLittle Rock | W86-55 | 8-0 | 1.000 | - | | Moby Arena · Fort Collins, CO |
| 9 | Sat Dec 4 | vsSaint Mary's | W74-58 | 9-0 | 1.000 | - | | Moby Arena · Fort Collins, CO |
| 10 | Sat Dec 11 | vsMississippi St | W66-63 | 10-0 | 1.000 | - | ESPNU | Moby Arena · Fort Collins, CO |
| 12 | Tue Dec 28 | atNew Mexico | PPD | 25-6 | .806 | #20 | | The Pit · Albuquerque, NM |
| 13 | Tue Jan 4 | vsAir Force | W67-59 | 11-0 | 1.000 | #20 | | Moby Arena · Fort Collins, CO |
| 14 | Fri Jan 7 | atBoise St | PPD | 25-6 | .806 | #20 | | ExtraMile Arena · Boise, ID |
| 15 | Sat Jan 8 | atSDSU | L49-79 | 11-1 | .917 | #20 | CBS | Viejas Arena · San Diego, CA |
| 16 | Wed Jan 12 | vsUtah State | W77-72 | 12-1 | .923 | - | CBS | Moby Arena · Fort Collins, CO |
| 17 | Sat Jan 15 | atSan Jose St | W78-42 | 13-1 | .929 | - | | Provident Credit Union Event Center · San Jose, CA |
| 18 | Wed Jan 19 | vsNew Mexico | W80-74 | 14-1 | .933 | - | CBS | Moby Arena · Fort Collins, CO |
| 19 | Sat Jan 22 | atAir Force | W73-53 | 15-1 | .938 | - | FS1 | Clune Arena · Colorado Springs, CO |
| 20 | Tue Jan 25 | vsNevada | W77-66 | 16-1 | .941 | - | FS1 | Moby Arena · Fort Collins, CO |
| 21 | Fri Jan 28 | vsUNLV | L74-88 | 16-2 | .889 | - | FS1 | Moby Arena · Fort Collins, CO |
| 22 | Mon Jan 31 | atWyoming | L78-84 (OT) | 16-3 | .842 | - | FS1 | Arena Auditorium · Laramie, WY |
| 23 | Fri Feb 4 | vsSDSU | W58-57 | 17-3 | .850 | - | FS1 | Moby Arena · Fort Collins, CO |
| 24 | Tue Feb 8 | atNevada | W82-72 | 18-3 | .857 | - | CBS | Lawlor Events Center · Reno, NV |
| 25 | Fri Feb 11 | vsFresno St | W65-50 | 19-3 | .864 | - | CBS | Moby Arena · Fort Collins, CO |
| 26 | Sun Feb 13 | atBoise St | W77-74 (OT) | 20-3 | .870 | - | FS1 | ExtraMile Arena · Boise, ID |
| 27 | Thu Feb 17 | atNew Mexico | W83-68 | 21-3 | .875 | - | FS1 | The Pit · Albuquerque, NM |
| 28 | Sat Feb 19 | atUNLV | L51-72 | 21-4 | .840 | - | CBS | Thomas & Mack Center · Las Vegas, NV |
| 29 | Wed Feb 23 | vsWyoming | W61-55 | 22-4 | .846 | - | CBS | Moby Arena · Fort Collins, CO |
| 30 | Sat Feb 26 | atUtah State | W66-55 | 23-4 | .852 | - | | Dee Glen Smith Spectrum · Logan, UT |
| 31 | Sat Mar 5 | vsBoise St | W71-68 | 24-4 | .857 | - | CBS | Moby Arena · Fort Collins, CO |
| 32 | Thu Mar 10 | vsUtah State | W53-51 | 25-4 | .862 | - | CBS | Thomas & Mack Center · Las Vegas, NV |
| 33 | Fri Mar 11 | vsSDSU | L58-63 | 25-5 | .833 | - | CBS | Thomas & Mack Center · Las Vegas, NV |
| 34 | Thu Mar 17 | vs#11Michigan | L63-75 | 25-6 | .806 | #6 | CBS | Moby Arena · Fort Collins, CO |
