| 1 | Mon Nov 4 | vs TBD | W82-68 | 1-0 | 1.000 | - | ESPN+ | Donald W. Reynolds Center · Tulsa, OK |
| 2 | Sat Nov 9 | vs AR-Pine Bluff | W103-80 | 2-0 | 1.000 | - | ESPN+ | Donald W. Reynolds Center · Tulsa, OK |
| 3 | Wed Nov 13 | vs Oral Roberts | W85-76 | 3-0 | 1.000 | - | ESPN+ | Donald W. Reynolds Center · Tulsa, OK |
| 4 | Sat Nov 16 | at Missouri St | L106-111 (3OT) | 3-1 | .750 | - | ESPN+ | Great Southern Bank Arena · Springfield, MO |
| 5 | Wed Nov 20 | vs Little Rock | L57-71 | 3-2 | .600 | - | ESPN+ | Donald W. Reynolds Center · Tulsa, OK |
| 6 | Sat Nov 23 | at Loyola Chicago | L53-89 | 3-3 | .500 | - | ESPN+ | Joseph J. Gentile Arena · Chicago, IL |
| 7 | Tue Nov 26 | at Detroit Mercy | W63-44 | 4-3 | .571 | - | | Calihan Hall · Detroit, MI |
| 8 | Wed Nov 27 | at Georgia St | L71-74 | 4-4 | .500 | - | | GSU Convocation Center · Atlanta, GA |
| 9 | Wed Dec 4 | vs Oklahoma St | L55-76 | 4-5 | .444 | - | ESPN+ | Donald W. Reynolds Center · Tulsa, OK |
| 10 | Sat Dec 7 | vs Southern | L66-70 | 4-6 | .400 | - | ESPN+ | Donald W. Reynolds Center · Tulsa, OK |
| 11 | Sat Dec 14 | at UCF | L75-88 | 4-7 | .364 | - | ESPNU | Addition Financial Arena · Orlando, FL |
| 12 | Sat Dec 21 | vs Miss Valley St | W93-48 | 5-7 | .417 | - | ESPN+ | Donald W. Reynolds Center · Tulsa, OK |
| 13 | Sat Dec 28 | vsTBD | W96-63 | 6-7 | .462 | - | ESPN+ | Donald W. Reynolds Center · Tulsa, OK |
| 14 | Wed Jan 1 | vs Rice | L64-70 | 6-8 | .429 | - | ESPN+ | Donald W. Reynolds Center · Tulsa, OK |
| 15 | Sat Jan 4 | at UAB | L51-83 | 6-9 | .400 | - | ESPNU | Bartow Arena · Birmingham, AL |
| 16 | Tue Jan 7 | at UTSA | W82-77 | 7-9 | .438 | - | ESPN+ | UTSA Convocation Center · San Antonio, TX |
| 17 | Sun Jan 12 | vs Charlotte | W69-63 | 8-9 | .471 | - | ESPN+ | Donald W. Reynolds Center · Tulsa, OK |
| 18 | Sat Jan 18 | at South Florida | L56-63 | 8-10 | .444 | - | ESPN+ | Yuengling Center · Tampa, FL |
| 19 | Tue Jan 21 | vs E Carolina | L76-85 (OT) | 8-11 | .421 | - | ESPN+ | Donald W. Reynolds Center · Tulsa, OK |
| 20 | Sun Jan 26 | vs Wichita St | W84-77 | 9-11 | .450 | - | ESPN+ | Donald W. Reynolds Center · Tulsa, OK |
| 21 | Wed Jan 29 | vsUAB | L68-78 | 9-12 | .429 | - | ESPN+ | Donald W. Reynolds Center · Tulsa, OK |
| 22 | Sun Feb 2 | at Tulane | L56-59 | 9-13 | .409 | - | ESPNU | Devlin Fieldhouse · New Orleans, LA |
| 23 | Wed Feb 5 | at #17Memphis | L71-83 | 9-14 | .391 | - | ESPN+ | FedExForum · Memphis, TN |
| 24 | Sat Feb 8 | vs FAU | L55-79 | 9-15 | .375 | - | ESPNU | Donald W. Reynolds Center · Tulsa, OK |
| 25 | Wed Feb 12 | at Temple | W80-74 | 10-15 | .400 | - | ESPN+ | Liacouras Center · Philadelphia, PA |
| 26 | Sat Feb 15 | vsUTSA | W80-76 | 11-15 | .423 | - | ESPNU | Donald W. Reynolds Center · Tulsa, OK |
| 27 | Wed Feb 19 | at North Texas | L44-63 | 11-16 | .407 | - | ESPN+ | The Super Pit · Denton, TX |
