| 1 | Mon Nov 4 | vs TBD | W103-77 | 1-0 | 1.000 | - | ESPN+ | UTSA Convocation Center · San Antonio, TX |
| 2 | Sat Nov 9 | vs North Dakota | PPD | 10-16 | .385 | - | ESPN+ | UTSA Convocation Center · San Antonio, TX |
| 3 | Tue Nov 12 | at Bradley | L72-85 | 1-1 | .500 | - | ESPN+ | Carver Arena · Peoria, IL |
| 4 | Sat Nov 16 | vs Little Rock | L64-81 | 1-2 | .333 | - | ESPN+ | UTSA Convocation Center · San Antonio, TX |
| 5 | Mon Nov 25 | at Troy | L72-86 | 1-3 | .250 | - | ESPN+ | Trojan Arena · Troy, AL |
| 6 | Wed Nov 27 | at Merrimack | W76-74 | 2-3 | .400 | - | ESPN+ | placeholder · sf, ca |
| 7 | Sat Nov 30 | vs Hou Christian | W78-71 | 3-3 | .500 | - | ESPN+ | UTSA Convocation Center · San Antonio, TX |
| 8 | Tue Dec 3 | at Saint Mary's | L74-82 (OT) | 3-4 | .429 | - | ESPN+ | University Credit Union Pavilion · Moraga, CA |
| 9 | Sat Dec 7 | at Arkansas | L60-75 | 10-16 | .385 | - | ESPN+ | Bud Walton Arena · Fayetteville, AR |
| 10 | Fri Dec 13 | vsNorth Dakota | W80-76 | 4-5 | .444 | - | ESPN+ | UTSA Convocation Center · San Antonio, TX |
| 11 | Sun Dec 15 | atNorth Dakota | W95-85 | 5-5 | .500 | - | | Betty Engelstad Sioux Center · Grand Forks, ND |
| 12 | Thu Dec 19 | vsTBD | W117-58 | 6-5 | .545 | - | ESPN+ | UTSA Convocation Center · San Antonio, TX |
| 13 | Sun Dec 29 | at Army | L75-78 | 6-6 | .500 | - | ESPN+ | Christl Arena · West Point, NY |
| 14 | Sat Jan 4 | at Tulane | L63-92 | 6-7 | .462 | - | ESPNU | Devlin Fieldhouse · New Orleans, LA |
| 15 | Tue Jan 7 | vs Tulsa | L77-82 | 6-8 | .429 | - | ESPN+ | UTSA Convocation Center · San Antonio, TX |
| 16 | Sat Jan 11 | vs Wichita St | W88-75 | 7-8 | .467 | - | ESPN+ | UTSA Convocation Center · San Antonio, TX |
| 17 | Tue Jan 14 | at Rice | W90-84 | 8-8 | .500 | - | ESPN+ | Tudor Fieldhouse · Houston, TX |
| 18 | Sat Jan 18 | vs North Texas | L57-72 | 8-9 | .471 | - | ESPN+ | UTSA Convocation Center · San Antonio, TX |
| 19 | Tue Jan 21 | at UAB | L78-81 | 8-10 | .444 | - | ESPN+ | Bartow Arena · Birmingham, AL |
| 20 | Sat Jan 25 | vs Temple | W88-79 | 9-10 | .474 | - | ESPN+ | UTSA Convocation Center · San Antonio, TX |
| 21 | Wed Jan 29 | at FAU | L74-94 | 9-11 | .450 | - | ESPN+ | FAU Arena · Boca Raton, FL |
| 22 | Sat Feb 1 | atNorth Texas | W54-50 | 10-11 | .476 | - | ESPN+ | The Super Pit · Denton, TX |
| 23 | Wed Feb 5 | vsTulane | L60-61 | 10-12 | .455 | - | ESPN+ | UTSA Convocation Center · San Antonio, TX |
| 24 | Sat Feb 8 | vs E Carolina | L79-80 | 10-13 | .435 | - | ESPNU | UTSA Convocation Center · San Antonio, TX |
| 25 | Wed Feb 12 | atWichita St | L64-69 | 10-14 | .417 | - | ESPN+ | Charles Koch Arena · Wichita, KS |
| 26 | Sat Feb 15 | atTulsa | L76-80 | 10-15 | .400 | - | ESPNU | Donald W. Reynolds Center · Tulsa, OK |
| 27 | Wed Feb 19 | vs South Florida | L73-78 | 10-16 | .385 | - | ESPN+ | UTSA Convocation Center · San Antonio, TX |
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