| 1 | Wed Nov 6 | vs Oral Roberts | W80-57 | 1-0 | 1.000 | - | B1G+ | Williams Arena · Minneapolis, MN |
| 2 | Sat Nov 9 | vs Omaha | W68-64 | 2-0 | 1.000 | - | Peacock | Williams Arena · Minneapolis, MN |
| 3 | Wed Nov 13 | vs North Texas | L51-54 | 2-1 | .667 | - | B1G+ | Williams Arena · Minneapolis, MN |
| 4 | Sat Nov 16 | vs Yale | W59-56 | 3-1 | .750 | - | BTN | Williams Arena · Minneapolis, MN |
| 5 | Tue Nov 19 | vs Cleveland St | W58-47 | 4-1 | .800 | - | BTN | Williams Arena · Minneapolis, MN |
| 6 | Mon Nov 25 | vs C Michigan | W68-65 | 5-1 | .833 | - | B1G+ | Williams Arena · Minneapolis, MN |
| 7 | Thu Nov 28 | at Wichita St | L66-68 (OT) | 5-2 | .714 | - | ESPN2 | Charles Koch Arena · Wichita, KS |
| 8 | Fri Nov 29 | at Wake Forest | L51-57 | 5-3 | .625 | - | ESPN2 | Lawrence Joel Veterans Memorial Coliseum · Winston-Salem, NC |
| 9 | Sun Dec 1 | vs Bethune | W79-62 | 6-3 | .667 | - | B1G+ | Williams Arena · Minneapolis, MN |
| 10 | Wed Dec 4 | vs Michigan St | L72-90 | 6-4 | .600 | - | BTN | Williams Arena · Minneapolis, MN |
| 11 | Mon Dec 9 | at Indiana | L67-82 | 6-5 | .545 | - | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
| 12 | Sat Dec 21 | vs Fairleigh | W74-60 | 7-5 | .583 | - | BTN | Williams Arena · Minneapolis, MN |
| 13 | Sun Dec 29 | vs Morgan St | W90-68 | 8-5 | .615 | - | Peacock | Williams Arena · Minneapolis, MN |
| 14 | Thu Jan 2 | vs #20Purdue | L61-81 | 8-6 | .571 | - | FS1 | Williams Arena · Minneapolis, MN |
| 15 | Mon Jan 6 | vs Ohio State | L88-89 (2OT) | 8-7 | .533 | - | FS1 | Williams Arena · Minneapolis, MN |
| 16 | Fri Jan 10 | at Wisconsin | L59-80 | 8-8 | .500 | - | Peacock | Kohl Center · Madison, WI |
| 17 | Mon Jan 13 | at Maryland | L71-77 | 8-9 | .471 | - | BTN | XFINITY Center · College Park, MD |
| 18 | Thu Jan 16 | vs #20Michigan | W84-81 (OT) | 9-9 | .500 | - | FS1 | Williams Arena · Minneapolis, MN |
| 19 | Tue Jan 21 | at Iowa | W72-67 | 10-9 | .526 | - | BTN | Carver-Hawkeye Arena · Iowa City, IA |
| 20 | Sat Jan 25 | vs #15Oregon | W77-69 | 11-9 | .550 | - | BTN | Williams Arena · Minneapolis, MN |
| 21 | Tue Jan 28 | at#7Michigan St | L51-73 | 11-10 | .524 | - | Peacock | Breslin Center · East Lansing, MI |
| 22 | Sat Feb 1 | vs Washington | L68-71 | 11-11 | .500 | - | BTN | Williams Arena · Minneapolis, MN |
| 23 | Tue Feb 4 | at Penn State | W69-61 | 12-11 | .522 | - | BTN | Bryce Jordan Center · University Park, PA |
| 24 | Sat Feb 8 | vs #23Illinois | L74-95 | 12-12 | .500 | - | BTN | Williams Arena · Minneapolis, MN |
| 25 | Sat Feb 15 | at USC | W69-66 | 13-12 | .520 | - | BTN | Galen Center · Los Angeles, CA |
| 26 | Tue Feb 18 | at UCLA | W64-61 | 14-12 | .538 | - | FS1 | Pauley Pavilion · Los Angeles, CA |
| 27 | Sat Feb 22 | vsPenn State | L60-69 | 14-13 | .519 | - | BTN | Williams Arena · Minneapolis, MN |
| 28 | Tue Feb 25 | vs Northwestern | L63-75 | 14-14 | .500 | - | Peacock | Williams Arena · Minneapolis, MN |
| 29 | Sat Mar 1 | at Nebraska | W67-65 | 15-14 | .517 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 30 | Wed Mar 5 | vs#12Wisconsin | L67-74 | 15-15 | .500 | - | BTN | Williams Arena · Minneapolis, MN |
| 31 | Sun Mar 9 | at Rutgers | L67-75 (OT) | 15-16 | .484 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 32 | Wed Mar 12 | vsNorthwestern | L64-72 | 15-17 | .469 | - | Peacock | Williams Arena · Minneapolis, MN |
