| 1 | Tue Nov 5 | vs Cleveland St | W85-50 | 1-0 | 1.000 | - | | Williams Arena · Minneapolis, MN |
| 2 | Sat Nov 9 | vsOklahoma | L62-71 | 1-1 | .500 | - | BTN | Williams Arena · Minneapolis, MN |
| 3 | Tue Nov 12 | atButler | L56-64 | 1-2 | .333 | - | FS1 | Hinkle Fieldhouse · Indianapolis, IN |
| 4 | Fri Nov 15 | atUtah | L69-73 | 1-3 | .250 | - | PACN | Jon M. Huntsman Center · Salt Lake City, UT |
| 5 | Thu Nov 21 | vsC Michigan | W82-57 | 2-3 | .400 | - | | Williams Arena · Minneapolis, MN |
| 6 | Sun Nov 24 | vsNorth Dakota | W79-56 | 3-3 | .500 | - | BTN | Williams Arena · Minneapolis, MN |
| 7 | Fri Nov 29 | vsDePaul | L68-73 | 3-4 | .429 | - | | Williams Arena · Minneapolis, MN |
| 8 | Mon Dec 2 | vsClemson | W78-60 | 4-4 | .500 | - | ESPN2 | Williams Arena · Minneapolis, MN |
| 9 | Mon Dec 9 | atIowa | L52-72 | 4-5 | .444 | - | BTN | Carver-Hawkeye Arena · Iowa City, IA |
| 10 | Sun Dec 15 | vs3Ohio State | W84-71 | 5-5 | .500 | - | BTN | Williams Arena · Minneapolis, MN |
| 11 | Sat Dec 21 | atOklahoma St | W86-66 | 6-5 | .545 | - | ESPN2 | Gallagher-Iba Arena · Stillwater, OK |
| 12 | Sat Dec 28 | vsFIU | W89-62 | 7-5 | .583 | - | BTN | Williams Arena · Minneapolis, MN |
| 13 | Thu Jan 2 | atPurdue | L78-83 (2OT) | 7-6 | .538 | - | BTN | Mackey Arena · West Lafayette, IN |
| 14 | Sun Jan 5 | vsNorthwestern | W77-68 | 8-6 | .571 | - | BTN | Williams Arena · Minneapolis, MN |
| 15 | Thu Jan 9 | at8Michigan St | L58-74 | 8-7 | .533 | - | ESPN2 | Breslin Center · East Lansing, MI |
| 16 | Sun Jan 12 | vs19Michigan | W75-67 | 9-7 | .563 | - | BTN | Williams Arena · Minneapolis, MN |
| 17 | Wed Jan 15 | vsPenn State | W75-69 | 10-7 | .588 | - | BTN | Williams Arena · Minneapolis, MN |
| 18 | Sun Jan 19 | atRutgers | L56-64 | 10-8 | .556 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 19 | Thu Jan 23 | atOhio State | W62-59 | 11-8 | .579 | - | FS1 | Value City Arena · Columbus, OH |
| 20 | Sun Jan 26 | vs11Michigan St | L52-70 | 11-9 | .550 | - | FOX | Williams Arena · Minneapolis, MN |
| 21 | Thu Jan 30 | at19Illinois | L51-59 | 11-10 | .524 | - | FS1 | State Farm Center · Champaign, IL |
| 22 | Wed Feb 5 | vsWisconsin | W70-52 | 12-10 | .545 | - | BTN | Williams Arena · Minneapolis, MN |
| 23 | Sat Feb 8 | at22Penn State | L77-83 | 12-11 | .522 | - | BTN | Bryce Jordan Center · University Park, PA |
| 24 | Sun Feb 16 | vs21Iowa | L55-58 | 12-12 | .500 | - | FS1 | Williams Arena · Minneapolis, MN |
| 25 | Wed Feb 19 | vsIndiana | L56-68 | 12-13 | .480 | - | BTN | Williams Arena · Minneapolis, MN |
| 26 | Sun Feb 23 | atNorthwestern | W83-57 | 13-13 | .500 | - | BTN | Welsh-Ryan Arena · Evanston, IL |
| 27 | Wed Feb 26 | vs9Maryland | L73-74 | 13-14 | .481 | - | BTN | Williams Arena · Minneapolis, MN |
| 28 | Sun Mar 1 | atWisconsin | L69-71 | 13-15 | .464 | - | BTN | Kohl Center · Madison, WI |
| 29 | Wed Mar 4 | atIndiana | L67-72 | 13-16 | .448 | - | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
| 30 | Sun Mar 8 | vsNebraska | W107-75 | 14-16 | .467 | - | BTN | Williams Arena · Minneapolis, MN |
| 31 | Wed Mar 11 | vsNorthwestern | W74-57 | 15-16 | .484 | - | BTN | Williams Arena · Minneapolis, MN |
