| 1 | Mon Nov 4 | at #19Texas | W80-72 | 1-0 | 1.000 | - | TNT | Moody Center · Austin, TX |
| 2 | Mon Nov 11 | vs Youngstown St | W81-47 | 2-0 | 1.000 | #21 | BTN | Value City Arena · Columbus, OH |
| 3 | Fri Nov 15 | at #23Texas A&M | L64-78 | 2-1 | .667 | #21 | SEC Network | Reed Arena · College Station, TX |
| 4 | Tue Nov 19 | vs Evansville | W80-30 | 3-1 | .750 | - | B1G+ | Value City Arena · Columbus, OH |
| 5 | Fri Nov 22 | vs Campbell | W104-60 | 4-1 | .800 | - | BTN | Value City Arena · Columbus, OH |
| 6 | Mon Nov 25 | vs Green Bay | W102-69 | 5-1 | .833 | - | BTN | Value City Arena · Columbus, OH |
| 7 | Fri Nov 29 | vs Pitt | L90-91 (OT) | 5-2 | .714 | - | Peacock | Value City Arena · Columbus, OH |
| 8 | Wed Dec 4 | at Maryland | L59-83 | 5-3 | .625 | - | BTN | XFINITY Center · College Park, MD |
| 9 | Sat Dec 7 | vs Rutgers | W80-66 | 6-3 | .667 | - | FS1 | Value City Arena · Columbus, OH |
| 10 | Sat Dec 14 | at #2Auburn | L53-91 | 6-4 | .600 | - | ESPN2 | Neville Arena · Auburn, AL |
| 11 | Tue Dec 17 | vs Valparaiso | W95-73 | 7-4 | .636 | - | Peacock | Value City Arena · Columbus, OH |
| 12 | Sat Dec 21 | vs #4Kentucky | W85-65 | 8-4 | .667 | - | CBS | Value City Arena · Columbus, OH |
| 13 | Sun Dec 29 | vs Indiana St | W103-83 | 9-4 | .692 | - | BTN | Value City Arena · Columbus, OH |
| 14 | Fri Jan 3 | vs #18Michigan St | L62-69 | 9-5 | .643 | - | FOX | Value City Arena · Columbus, OH |
| 15 | Mon Jan 6 | at Minnesota | W89-88 (2OT) | 10-5 | .667 | - | FS1 | Williams Arena · Minneapolis, MN |
| 16 | Thu Jan 9 | vs #15Oregon | L71-73 | 10-6 | .625 | - | BTN | Value City Arena · Columbus, OH |
| 17 | Tue Jan 14 | at #24Wisconsin | L68-70 | 10-7 | .588 | - | Peacock | Kohl Center · Madison, WI |
| 18 | Fri Jan 17 | vs Indiana | L76-77 (OT) | 10-8 | .556 | - | FOX | Value City Arena · Columbus, OH |
| 19 | Tue Jan 21 | at #11Purdue | W73-70 | 11-8 | .579 | - | Peacock | Mackey Arena · West Lafayette, IN |
| 20 | Mon Jan 27 | vs Iowa | W82-65 | 12-8 | .600 | - | FS1 | Value City Arena · Columbus, OH |
| 21 | Thu Jan 30 | at Penn State | W83-64 | 13-8 | .619 | - | FS1 | Bryce Jordan Center · University Park, PA |
| 22 | Sun Feb 2 | at #18Illinois | L79-87 | 13-9 | .591 | - | CBS | State Farm Center · Champaign, IL |
| 23 | Thu Feb 6 | vs#18Maryland | W73-70 | 14-9 | .609 | - | FS1 | Value City Arena · Columbus, OH |
| 24 | Sun Feb 9 | at Nebraska | L71-79 | 14-10 | .583 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 25 | Wed Feb 12 | vs Washington | W93-69 | 15-10 | .600 | - | BTN | Value City Arena · Columbus, OH |
| 26 | Sun Feb 16 | vs #20Michigan | L83-86 | 15-11 | .577 | - | CBS | Value City Arena · Columbus, OH |
| 27 | Thu Feb 20 | vs Northwestern | L49-70 | 15-12 | .556 | - | FS1 | Value City Arena · Columbus, OH |
UCLA
USC