| 1 | Mon Nov 3 | at UMass | W78-72 | 1-0 | 1.000 | - | ESPN+ | William D. Mullins Memorial Center · Amherst, MA |
| 2 | Sat Nov 8 | atToledo | W85-73 | 2-0 | 1.000 | - | ESPN+ | Savage Arena · Toledo, OH |
| 3 | Wed Nov 12 | vsElon | W96-89 | 3-0 | 1.000 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 4 | Sat Nov 15 | atVirginia | L78-104 | 3-1 | .750 | - | ACC Extra | John Paul Jones Arena · Charlottesville, VA |
| 5 | Thu Nov 20 | vsAR-Pine Bluff | W98-70 | 4-1 | .800 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 6 | Sun Nov 23 | vsMercyhurst | W69-60 | 5-1 | .833 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 7 | Wed Nov 26 | vsLipscomb | L67-90 | 5-2 | .714 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 8 | Wed Dec 3 | atUNC Wilmington | L69-70 | 5-3 | .625 | - | | Trask Coliseum · Wilmington, NC |
| 9 | Sat Dec 6 | atOhio | L81-88 | 5-4 | .556 | - | ESPN+ | Convocation Center (OH) · Athens, OH |
| 10 | Wed Dec 10 | vsWestern KY | W77-61 | 6-4 | .600 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 11 | Sat Dec 13 | vsWright St | W76-74 | 7-4 | .636 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 12 | Sat Dec 20 | atTroy | L63-70 | 7-5 | .583 | - | ESPN+ | Trojan Arena · Troy, AL |
| 13 | Tue Dec 23 | vsTBD | W102-52 | 8-5 | .615 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 14 | Wed Dec 31 | vsGeorgia St | W84-80 | 9-5 | .643 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 15 | Sat Jan 3 | vsAppalachian St | W88-81 | 10-5 | .667 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 16 | Wed Jan 7 | atJMU | W66-64 | 11-5 | .688 | - | ESPN+ | Atlantic Union Bank Center · Harrisonburg, VA |
| 17 | Sat Jan 10 | atGeorgia St | L73-81 | 11-6 | .647 | - | ESPN+ | GSU Convocation Center · Atlanta, GA |
| 18 | Wed Jan 14 | vsCoast Car | L83-85 | 11-7 | .611 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 19 | Sat Jan 17 | vsJMU | W77-72 | 12-7 | .632 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 20 | Thu Jan 22 | vsUL Monroe | W115-60 | 13-7 | .650 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 21 | Wed Jan 28 | atTexas St | L68-72 | 13-8 | .619 | - | ESPN+ | Strahan Arena · San Marcos, TX |
| 22 | Sat Jan 31 | atArkansas St | W70-61 | 14-8 | .636 | - | ESPN+ | First National Bank Arena · Jonesboro, AR |
| 23 | Wed Feb 4 | vsSouthern Miss | W81-77 | 15-8 | .652 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 24 | Sat Feb 7 | vs23Miami OH | L74-90 | 15-9 | .625 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 25 | Wed Feb 11 | atOld Dominion | W81-79 | 16-9 | .640 | - | ESPN+ | Chartway Arena · Norfolk, VA |
| 26 | Sat Feb 14 | atGeorgia So | L87-101 | 16-10 | .615 | - | ESPNU | W.S. Hanner Fieldhouse · Statesboro, GA |
| 27 | Mon Feb 16 | vsSouth Alabama | W84-80 | 17-10 | .630 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 28 | Thu Feb 19 | atAppalachian St | W94-93 | 18-10 | .643 | - | ESPN+ | Holmes Convocation Center · Boone, NC |
| 29 | Sat Feb 21 | atCoast Car | L75-79 | 18-11 | .621 | - | ESPN+ | The HTC Center · Conway, SC |
| 30 | Tue Feb 24 | vsOld Dominion | W97-88 | 19-11 | .633 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 31 | Fri Feb 27 | vsGeorgia So | L82-99 | 19-12 | .613 | - | ESPN2 | Cam Henderson Center · Huntington, WV |
