| 1 | Fri Nov 12 | vs Wright St | W96-88 | 1-0 | 1.000 | - | | Cam Henderson Center · Huntington, WV |
| 2 | Mon Nov 15 | vs TBD | W80-58 | 2-0 | 1.000 | - | | Cam Henderson Center · Huntington, WV |
| 3 | Thu Nov 18 | vs Campbell | L65-67 | 2-1 | .667 | - | | Cam Henderson Center · Huntington, WV |
| 4 | Sun Nov 21 | vs Jackson St | W80-66 | 3-1 | .750 | - | | Cam Henderson Center · Huntington, WV |
| 5 | Tue Nov 23 | vs Louisiana | W93-79 | 4-1 | .800 | - | | Cam Henderson Center · Huntington, WV |
| 6 | Sat Nov 27 | at Indiana | L79-90 | 4-2 | .667 | - | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
| 7 | Wed Dec 1 | at Akron | L86-88 | 4-3 | .571 | - | | James A. Rhodes Arena · Akron, OH |
| 8 | Sat Dec 4 | vs Duquesne | W72-71 | 5-3 | .625 | - | | Cam Henderson Center · Huntington, WV |
| 9 | Wed Dec 8 | vsTBD | W100-57 | 6-3 | .667 | - | | Cam Henderson Center · Huntington, WV |
| 10 | Sat Dec 11 | at E Kentucky | W80-69 | 7-3 | .700 | - | | McBrayer Arena · Richmond, KY |
| 11 | Wed Dec 15 | at Ohio | L65-75 | 7-4 | .636 | - | | Convocation Center (OH) · Athens, OH |
| 12 | Sat Dec 18 | vs Northern Iowa | L60-75 | 7-5 | .583 | - | | Cam Henderson Center · Huntington, WV |
| 13 | Tue Dec 21 | at Toledo | L63-95 | 7-6 | .538 | - | | Savage Arena · Toledo, OH |
| 14 | Thu Dec 30 | at Louisiana Tech | L56-79 | 7-7 | .500 | - | ESPN2 | Thomas Assembly Center · Ruston, LA |
| 15 | Sat Jan 1 | at Southern Miss | PPD | 12-21 | .364 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 16 | Sat Jan 8 | vs FAU | L77-90 | 7-8 | .467 | - | | Cam Henderson Center · Huntington, WV |
| 17 | Thu Jan 13 | vs North Texas | L65-69 | 7-9 | .438 | - | | Cam Henderson Center · Huntington, WV |
| 18 | Sat Jan 15 | vs Rice | L77-87 | 7-10 | .412 | - | | Cam Henderson Center · Huntington, WV |
| 19 | Thu Jan 20 | at FIU | L66-70 | 7-11 | .389 | - | | Ocean Bank Convocation Center · Miami, FL |
| 20 | Sat Jan 22 | atFAU | L60-71 | 7-12 | .368 | - | | FAU Arena · Boca Raton, FL |
| 21 | Thu Jan 27 | vs MTSU | L79-81 | 7-13 | .350 | - | | Cam Henderson Center · Huntington, WV |
| 22 | Sat Jan 29 | vs UAB | W84-81 | 8-13 | .381 | - | | Cam Henderson Center · Huntington, WV |
| 23 | Thu Feb 3 | at Old Dominion | L64-79 | 8-14 | .364 | - | CBS | Chartway Arena · Norfolk, VA |
| 24 | Sat Feb 5 | at Charlotte | L64-88 | 8-15 | .348 | - | | Dale F. Halton Arena · Charlotte, NC |
| 25 | Thu Feb 10 | vsFIU | L71-72 | 8-16 | .333 | - | | Cam Henderson Center · Huntington, WV |
| 26 | Sun Feb 13 | at UTEP | W88-79 | 9-16 | .360 | - | | Don Haskins Center · El Paso, TX |
| 27 | Thu Feb 17 | vsOld Dominion | W67-63 | 10-16 | .385 | - | | Cam Henderson Center · Huntington, WV |
| 28 | Sat Feb 19 | vsCharlotte | L84-99 | 10-17 | .370 | - | | Cam Henderson Center · Huntington, WV |
| 29 | Mon Feb 21 | atSouthern Miss | W74-60 | 11-17 | .393 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 30 | Thu Feb 24 | atMTSU | L65-74 | 11-18 | .379 | - | | Murphy Center · Murfreesboro, TN |
| 31 | Wed Mar 2 | vs Western KY | L72-86 | 11-19 | .367 | - | ESPNU | Cam Henderson Center · Huntington, WV |
| 32 | Sat Mar 5 | atWestern KY | L69-78 | 11-20 | .355 | - | | E. A. Diddle Arena · Bowling Green, KY |
| 33 | Tue Mar 8 | atFIU | W74-62 | 12-20 | .375 | - | | Ocean Bank Convocation Center · Miami, FL |
| 34 | Wed Mar 9 | atLouisiana Tech | L67-77 | 12-21 | .364 | - | | Thomas Assembly Center · Ruston, LA |
