| 1 | Mon Nov 4 | at Arkansas St | L75-80 (OT) | 0-1 | .000 | - | ESPN+ | First National Bank Arena · Jonesboro, AR |
| 2 | Fri Nov 8 | vs TBD | W88-57 | 1-1 | .500 | - | | James A. Rhodes Arena · Akron, OH |
| 3 | Tue Nov 12 | at Saint Mary's | L68-87 | 1-2 | .333 | - | ESPN+ | University Credit Union Pavilion · Moraga, CA |
| 4 | Fri Nov 22 | vs Lamar | W79-72 | 2-2 | .500 | - | ESPN+ | James A. Rhodes Arena · Akron, OH |
| 5 | Sat Nov 23 | vs Omaha | W92-84 | 3-2 | .600 | - | ESPN+ | James A. Rhodes Arena · Akron, OH |
| 6 | Sun Nov 24 | vs Alabama St | W97-78 | 4-2 | .667 | - | ESPN+ | James A. Rhodes Arena · Akron, OH |
| 7 | Tue Dec 3 | vs N Kentucky | W86-73 | 5-2 | .714 | - | | James A. Rhodes Arena · Akron, OH |
| 8 | Sat Dec 7 | vsTBD | W101-48 | 6-2 | .750 | - | | James A. Rhodes Arena · Akron, OH |
| 9 | Sun Dec 15 | at Milwaukee | L81-100 | 6-3 | .667 | - | ESPN+ | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 10 | Fri Dec 20 | at Yale | L58-74 | 6-4 | .600 | - | | John J. Lee Amphitheater · New Haven, CT |
| 11 | Sat Dec 21 | at Jackson St | W68-50 | 7-4 | .636 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 12 | Mon Dec 30 | at Princeton | L75-76 | 7-5 | .583 | - | ESPN+ | Jadwin Gymnasium · Princeton, NJ |
| 13 | Fri Jan 3 | at Bowling Green | W71-68 | 8-5 | .615 | - | CBS | Stroh Center · Bowling Green, OH |
| 14 | Tue Jan 7 | vs C Michigan | W87-71 | 9-5 | .643 | - | ESPN+ | James A. Rhodes Arena · Akron, OH |
| 15 | Sat Jan 11 | at E Michigan | W105-81 | 10-5 | .667 | - | ESPN+ | Convocation Center (MI) · Ypsilanti, MI |
| 16 | Tue Jan 14 | vs Toledo | W85-78 | 11-5 | .688 | - | ESPN+ | James A. Rhodes Arena · Akron, OH |
| 17 | Fri Jan 17 | vs Ohio | W92-80 | 12-5 | .706 | - | CBS | James A. Rhodes Arena · Akron, OH |
| 18 | Tue Jan 21 | at Buffalo | W90-58 | 13-5 | .722 | - | ESPN+ | Alumni Arena · Buffalo, NY |
| 19 | Sat Jan 25 | vs Miami OH | W102-75 | 14-5 | .737 | - | ESPN+ | James A. Rhodes Arena · Akron, OH |
| 20 | Tue Jan 28 | at N Illinois | W80-70 | 15-5 | .750 | - | ESPN+ | NIU Convocation Center · Dekalb, IL |
| 21 | Fri Jan 31 | at Kent State | W85-71 | 16-5 | .762 | - | CBS | M.A.C. Center · Kent, OH |
| 22 | Tue Feb 4 | vs Ball State | W81-73 | 17-5 | .773 | - | ESPN+ | James A. Rhodes Arena · Akron, OH |
| 23 | Sat Feb 8 | vs South Alabama | W80-67 | 18-5 | .783 | - | ESPN+ | James A. Rhodes Arena · Akron, OH |
| 24 | Tue Feb 11 | vs W Michigan | W105-92 | 19-5 | .792 | - | ESPN+ | James A. Rhodes Arena · Akron, OH |
| 25 | Sat Feb 15 | atC Michigan | W85-82 | 20-5 | .800 | - | ESPN+ | McGuirk Arena · Mount Pleasant, MI |
| 26 | Tue Feb 18 | vsN Illinois | W73-63 | 21-5 | .808 | - | ESPN+ | James A. Rhodes Arena · Akron, OH |
| 27 | Sat Feb 22 | atOhio | L67-84 | 21-6 | .778 | - | ESPN2 | Convocation Center (OH) · Athens, OH |
| 28 | Tue Feb 25 | atBall State | W87-82 | 22-6 | .786 | - | ESPN+ | Worthen Arena · Muncie, IN |
| 29 | Fri Feb 28 | vsKent State | W77-72 | 23-6 | .793 | - | ESPN2 | James A. Rhodes Arena · Akron, OH |
| 30 | Tue Mar 4 | atToledo | W96-87 | 24-6 | .800 | - | ESPN+ | Savage Arena · Toledo, OH |
| 31 | Fri Mar 7 | vsBuffalo | W88-70 | 25-6 | .806 | - | ESPN+ | James A. Rhodes Arena · Akron, OH |
| 32 | Thu Mar 13 | vsBowling Green | W96-67 | 26-6 | .813 | - | ESPN+ | James A. Rhodes Arena · Akron, OH |
| 33 | Fri Mar 14 | vsToledo | W100-90 | 27-6 | .818 | - | CBS | James A. Rhodes Arena · Akron, OH |
| 34 | Sat Mar 15 | vsMiami OH | W76-74 | 28-6 | .824 | - | ESPN2 | James A. Rhodes Arena · Akron, OH |
| 35 | Fri Mar 21 | at #4Arizona | L65-93 | 28-7 | .800 | #13 | truTV | McKale Center · Tucson, AZ |
