| 1 | Tue Nov 5 | vs Evansville | W80-63 | 1-0 | 1.000 | - | ESPN+ | The Super Pit · Denton, TX |
| 2 | Thu Nov 7 | vs TBD | W80-38 | 2-0 | 1.000 | - | ESPN+ | The Super Pit · Denton, TX |
| 3 | Wed Nov 13 | at Minnesota | W54-51 | 3-0 | 1.000 | - | B1G+ | Williams Arena · Minneapolis, MN |
| 4 | Mon Nov 18 | at McNeese | L61-68 | 3-1 | .750 | - | ESPN+ | Legacy Center · Lake Charles, LA |
| 5 | Thu Nov 21 | vsTBD | W73-66 | 4-1 | .800 | - | ESPN+ | The Super Pit · Denton, TX |
| 6 | Mon Nov 25 | vs Oregon St | W58-55 | 5-1 | .833 | - | ESPN+ | The Super Pit · Denton, TX |
| 7 | Thu Nov 28 | vs Northern Iowa | W68-48 | 6-1 | .857 | - | ESPNU | The Super Pit · Denton, TX |
| 8 | Fri Nov 29 | vs Utah State | L57-61 | 6-2 | .750 | - | ESPN2 | The Super Pit · Denton, TX |
| 9 | Fri Dec 6 | at High Point | L71-76 | 6-3 | .667 | - | ESPN+ | Nido and Mariana Qubein Arena · High Point, NC |
| 10 | Wed Dec 18 | vs Miss Valley St | W83-42 | 7-3 | .700 | - | ESPN+ | The Super Pit · Denton, TX |
| 11 | Fri Dec 20 | vs Appalachian St | W68-64 | 8-3 | .727 | - | ESPN+ | The Super Pit · Denton, TX |
| 12 | Sun Dec 22 | vs Hou Christian | W62-46 | 9-3 | .750 | - | ESPN+ | The Super Pit · Denton, TX |
| 13 | Tue Dec 31 | vs UAB | W78-75 | 10-3 | .769 | - | ESPNU | The Super Pit · Denton, TX |
| 14 | Sun Jan 5 | at #21Memphis | L64-68 | 10-4 | .714 | - | ESPN | FedExForum · Memphis, TN |
| 15 | Wed Jan 8 | vs Rice | W81-59 | 11-4 | .733 | - | ESPNU | The Super Pit · Denton, TX |
| 16 | Tue Jan 14 | at E Carolina | W69-60 | 12-4 | .750 | - | ESPN+ | Williams Arena at Minges Coliseum · Greenville, NC |
| 17 | Sat Jan 18 | at UTSA | W72-57 | 13-4 | .765 | - | ESPN+ | UTSA Convocation Center · San Antonio, TX |
| 18 | Wed Jan 22 | vs Temple | W76-67 | 14-4 | .778 | - | ESPN+ | The Super Pit · Denton, TX |
| 19 | Sun Jan 26 | vs FAU | W77-64 | 15-4 | .789 | - | ESPNU | The Super Pit · Denton, TX |
| 20 | Wed Jan 29 | at Wichita St | W58-54 | 16-4 | .800 | - | ESPN+ | Charles Koch Arena · Wichita, KS |
| 21 | Sat Feb 1 | vsUTSA | L50-54 | 16-5 | .762 | - | ESPN+ | The Super Pit · Denton, TX |
| 22 | Mon Feb 3 | atUAB | L61-64 | 16-6 | .727 | - | ESPN2 | Bartow Arena · Birmingham, AL |
| 23 | Sat Feb 8 | vs Tulane | W76-66 | 17-6 | .739 | - | ESPN+ | The Super Pit · Denton, TX |
| 24 | Tue Feb 11 | atRice | W67-61 | 18-6 | .750 | - | ESPNU | Tudor Fieldhouse · Houston, TX |
| 25 | Wed Feb 19 | vs Tulsa | W63-44 | 19-6 | .760 | - | ESPN+ | The Super Pit · Denton, TX |
South Florida
Charlotte