| 1 | Tue Nov 7 | vs Northern Iowa | W83-77 (OT) | 1-0 | 1.000 | - | | The Super Pit · Denton, TX |
| 2 | Sat Nov 11 | vs Omaha | W75-64 | 2-0 | 1.000 | - | | The Super Pit · Denton, TX |
| 3 | Thu Nov 16 | vs St John's | L52-53 | 2-1 | .667 | - | ESPNU | The Super Pit · Denton, TX |
| 4 | Fri Nov 17 | at LSU | L62-66 | 2-2 | .500 | - | ESPNU | Pete Maravich Assembly Center · Baton Rouge, LA |
| 5 | Sun Nov 19 | at Towson | W65-39 | 3-2 | .600 | - | | SECU Arena · Towson, MD |
| 6 | Sun Nov 26 | vs TBD | W79-50 | 4-2 | .667 | - | | The Super Pit · Denton, TX |
| 7 | Sat Dec 2 | vs Miss Valley St | W79-48 | 5-2 | .714 | - | | The Super Pit · Denton, TX |
| 8 | Tue Dec 5 | at Boise St | L64-69 | 5-3 | .625 | - | | ExtraMile Arena · Boise, ID |
| 9 | Sun Dec 10 | at Fordham | L59-60 | 5-4 | .556 | - | | Rose Hill Gymnasium · Bronx, NY |
| 10 | Sun Dec 17 | at Mississippi St | L54-72 | 5-5 | .500 | - | | Humphrey Coliseum · Starkville, MS |
| 11 | Sat Dec 23 | vs UT Arlington | W78-52 | 6-5 | .545 | - | | The Super Pit · Denton, TX |
| 12 | Sat Dec 30 | vsTBD | W80-57 | 7-5 | .583 | - | | The Super Pit · Denton, TX |
| 13 | Thu Jan 4 | at Wichita St | W74-62 | 8-5 | .615 | - | ESPN2 | Charles Koch Arena · Wichita, KS |
| 14 | Sat Jan 6 | vs Tulane | W70-56 | 9-5 | .643 | - | ESPNU | The Super Pit · Denton, TX |
| 15 | Sat Jan 13 | vs Temple | W69-51 | 10-5 | .667 | - | ESPN2 | The Super Pit · Denton, TX |
| 16 | Wed Jan 17 | at E Carolina | W60-59 | 11-5 | .688 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 17 | Sat Jan 20 | at Charlotte | L44-56 | 11-6 | .647 | - | | Dale F. Halton Arena · Charlotte, NC |
| 18 | Thu Jan 25 | vs SMU | W68-66 | 12-6 | .667 | - | ESPN2 | The Super Pit · Denton, TX |
| 19 | Sun Jan 28 | at #22FAU | L63-66 | 12-7 | .632 | - | ESPN2 | FAU Arena · Boca Raton, FL |
| 20 | Wed Jan 31 | vs UAB | L79-82 (OT) | 12-8 | .600 | - | ESPNU | The Super Pit · Denton, TX |
| 21 | Sat Feb 3 | vs South Florida | L55-60 | 12-9 | .571 | - | | The Super Pit · Denton, TX |
| 22 | Wed Feb 7 | at Tulsa | W68-55 | 13-9 | .591 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 23 | Sun Feb 11 | atSMU | L68-71 | 13-10 | .565 | - | ESPNU | Moody Coliseum · Dallas, TX |
| 24 | Thu Feb 15 | vs Memphis | W76-66 | 14-10 | .583 | - | | The Super Pit · Denton, TX |
| 25 | Sun Feb 18 | atUAB | L62-71 | 14-11 | .560 | - | | Bartow Arena · Birmingham, AL |
| 26 | Sat Feb 24 | vs UTSA | L62-64 | 14-12 | .538 | - | ESPNU | The Super Pit · Denton, TX |
| 27 | Wed Feb 28 | atTulane | W80-76 | 15-12 | .556 | - | | Devlin Fieldhouse · New Orleans, LA |
| 28 | Sun Mar 3 | vsE Carolina | W84-69 | 16-12 | .571 | - | | The Super Pit · Denton, TX |
| 29 | Wed Mar 6 | vsFAU | L76-80 | 16-13 | .552 | - | | The Super Pit · Denton, TX |
| 30 | Sat Mar 9 | at Rice | W71-55 | 17-13 | .567 | - | | Tudor Fieldhouse · Houston, TX |
| 31 | Thu Mar 14 | vsTulane | W81-71 | 18-13 | .581 | - | ESPNU | The Super Pit · Denton, TX |
| 32 | Fri Mar 15 | atFAU | L71-77 | 18-14 | .563 | - | ESPNU | FAU Arena · Boca Raton, FL |
| 33 | Tue Mar 19 | atLSU | W84-77 | 19-14 | .576 | - | SEC Network | Pete Maravich Assembly Center · Baton Rouge, LA |
| 34 | Sat Mar 23 | at Seton Hall | L58-72 | 19-15 | .559 | - | ESPN2 | Prudential Center · Newark, NJ |
