| 1 | Mon Nov 4 | at #21Florida | L83-98 | 0-1 | .000 | - | SEC Network | O'Connell Center · Gainesville, FL |
| 2 | Fri Nov 8 | at Charleston | L71-86 | 0-2 | .000 | - | FloSports | TD Arena · Charleston, SC |
| 3 | Tue Nov 12 | vs AR-Pine Bluff | W85-69 | 1-2 | .333 | - | ESPN+ | Yuengling Center · Tampa, FL |
| 4 | Fri Nov 15 | vs W Georgia | W74-55 | 2-2 | .500 | - | ESPN+ | Yuengling Center · Tampa, FL |
| 5 | Thu Nov 21 | at Portland | W74-68 | 3-2 | .600 | - | ESPN2 | Chiles Center · Portland, OR |
| 6 | Fri Nov 22 | vs MTSU | L88-95 | 3-3 | .500 | - | ESPN2 | Yuengling Center · Tampa, FL |
| 7 | Sun Nov 24 | at Wright St | W73-72 | 4-3 | .571 | - | ESPN2 | Nutter Center · Dayton, OH |
| 8 | Tue Dec 3 | vs Stetson | W74-72 | 5-3 | .625 | - | ESPN+ | Yuengling Center · Tampa, FL |
| 9 | Sat Dec 7 | at Loyola Chicago | L72-74 | 5-4 | .556 | - | USA Net | Joseph J. Gentile Arena · Chicago, IL |
| 10 | Sat Dec 14 | at Utah State | L67-88 | 5-5 | .500 | - | | Dee Glen Smith Spectrum · Logan, UT |
| 11 | Wed Dec 18 | vs Bethune | L69-77 | 5-6 | .455 | - | ESPN+ | Yuengling Center · Tampa, FL |
| 12 | Sat Dec 21 | vs E Texas A&M | W88-62 | 6-6 | .500 | - | ESPN+ | Yuengling Center · Tampa, FL |
| 13 | Sat Dec 28 | vs TBD | W106-49 | 7-6 | .538 | - | ESPN+ | Yuengling Center · Tampa, FL |
| 14 | Tue Dec 31 | vs E Carolina | W75-69 | 8-6 | .571 | - | ESPN+ | Yuengling Center · Tampa, FL |
| 15 | Mon Jan 6 | at Wichita St | W91-72 | 9-6 | .600 | - | ESPN2 | Charles Koch Arena · Wichita, KS |
| 16 | Sat Jan 11 | at Tulane | L70-73 | 9-7 | .563 | - | ESPN+ | Devlin Fieldhouse · New Orleans, LA |
| 17 | Wed Jan 15 | vs UAB | L83-92 | 9-8 | .529 | - | ESPN+ | Yuengling Center · Tampa, FL |
| 18 | Sat Jan 18 | vs Tulsa | W63-56 | 10-8 | .556 | - | ESPN+ | Yuengling Center · Tampa, FL |
| 19 | Wed Jan 22 | at Charlotte | L61-69 | 10-9 | .526 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 20 | Sat Jan 25 | atE Carolina | L55-64 | 10-10 | .500 | - | ESPN+ | Williams Arena at Minges Coliseum · Greenville, NC |
| 21 | Tue Jan 28 | vs Rice | W69-64 | 11-10 | .524 | - | ESPNU | Yuengling Center · Tampa, FL |
| 22 | Sun Feb 2 | at FAU | L72-94 | 11-11 | .500 | - | ESPN2 | FAU Arena · Boca Raton, FL |
| 23 | Thu Feb 6 | vs Temple | W100-91 (2OT) | 12-11 | .522 | - | ESPN2 | Yuengling Center · Tampa, FL |
| 24 | Sun Feb 9 | vsWichita St | L70-75 | 12-12 | .500 | - | ESPN+ | Yuengling Center · Tampa, FL |
| 25 | Thu Feb 13 | vs #14Memphis | L65-80 | 12-13 | .480 | - | ESPN2 | Yuengling Center · Tampa, FL |
| 26 | Sun Feb 16 | atUAB | L78-85 | 12-14 | .462 | - | ESPN2 | Bartow Arena · Birmingham, AL |
| 27 | Wed Feb 19 | at UTSA | W78-73 | 13-14 | .481 | - | ESPN+ | UTSA Convocation Center · San Antonio, TX |
| 28 | Sun Feb 23 | vs North Texas | L57-64 | 13-15 | .464 | - | ESPNU | Yuengling Center · Tampa, FL |
| 29 | Wed Feb 26 | atTemple | L71-73 | 13-16 | .448 | - | ESPN+ | Liacouras Center · Philadelphia, PA |
| 30 | Sun Mar 2 | vsFAU | L63-69 | 13-17 | .433 | - | ESPN2 | Yuengling Center · Tampa, FL |
| 31 | Fri Mar 7 | at#16Memphis | L68-84 | 13-18 | .419 | - | ESPN2 | FedExForum · Memphis, TN |
| 32 | Thu Mar 13 | atWichita St | L68-73 | 13-19 | .406 | - | ESPNU | Charles Koch Arena · Wichita, KS |
