| 1 | Tue Nov 9 | vs Bethune | W75-54 | 1-0 | 1.000 | - | | Yuengling Center · Tampa, FL |
| 2 | Sat Nov 13 | vs Georgia So | L41-53 | 1-1 | .500 | - | | Yuengling Center · Tampa, FL |
| 3 | Mon Nov 15 | vs NC A&T | W56-54 | 2-1 | .667 | - | | Yuengling Center · Tampa, FL |
| 4 | Fri Nov 19 | vs #21Auburn | L52-58 | 2-2 | .500 | - | | Yuengling Center · Tampa, FL |
| 5 | Wed Nov 24 | vs Hampton | W58-52 | 3-2 | .600 | - | | Yuengling Center · Tampa, FL |
| 6 | Mon Nov 29 | at Boston College | L49-64 | 3-3 | .500 | - | ACC Network | Silvio O. Conte Forum · Chestnut Hill, MA |
| 7 | Fri Dec 3 | vs SC State | L64-65 | 3-4 | .429 | - | | Yuengling Center · Tampa, FL |
| 8 | Tue Dec 14 | vs Austin Peay | W60-51 | 4-4 | .500 | - | | Yuengling Center · Tampa, FL |
| 9 | Sat Dec 18 | at Florida | L55-66 | 4-5 | .444 | - | | Exactech Arena at Stephen C. O'Connell Center · Gainesville, FL |
| 10 | Wed Dec 22 | vs BYU | L39-54 | 4-6 | .400 | - | ESPNU | Yuengling Center · Tampa, FL |
| 11 | Fri Dec 24 | at Hawai'i | W76-69 | 5-6 | .455 | - | ESPN2 | Stan Sheriff Center · Honolulu, HI |
| 12 | Sat Dec 25 | vs Wyoming | L57-77 | 5-7 | .417 | - | ESPNU | Yuengling Center · Tampa, FL |
| 14 | Sat Jan 1 | vs E Carolina | PPD | 8-23 | .258 | - | | Yuengling Center · Tampa, FL |
| 15 | Wed Jan 5 | vs #12Houston | L66-83 | 5-8 | .385 | - | | Yuengling Center · Tampa, FL |
| 16 | Sat Jan 8 | at Tulane | L54-68 | 5-9 | .357 | - | ESPNU | Devlin Fieldhouse · New Orleans, LA |
| 17 | Wed Jan 12 | at SMU | L65-77 | 5-10 | .333 | - | | Moody Coliseum · Dallas, TX |
| 18 | Sat Jan 15 | vs UCF | W75-51 | 6-10 | .375 | - | ESPNU | Yuengling Center · Tampa, FL |
| 19 | Tue Jan 18 | at#10Houston | L55-74 | 6-11 | .353 | - | | Fertitta Center · Houston, TX |
| 20 | Sat Jan 22 | vs Temple | PPD | 8-23 | .258 | - | | Yuengling Center · Tampa, FL |
| 21 | Wed Jan 26 | vsSMU | L54-74 | 6-12 | .333 | - | | Yuengling Center · Tampa, FL |
| 22 | Sat Jan 29 | at Tulsa | L45-76 | 6-13 | .316 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 23 | Thu Feb 3 | atUCF | L49-68 | 6-14 | .300 | - | | Addition Financial Arena · Orlando, FL |
| 24 | Mon Feb 7 | vsTemple | W52-49 | 7-14 | .333 | - | | Yuengling Center · Tampa, FL |
| 25 | Wed Feb 9 | vs Cincinnati | L59-70 | 7-15 | .318 | - | | Yuengling Center · Tampa, FL |
| 26 | Sat Feb 12 | at Wichita St | L69-73 | 7-16 | .304 | - | ESPNU | Charles Koch Arena · Wichita, KS |
| 27 | Tue Feb 15 | vsTulane | L57-76 | 7-17 | .292 | - | | Yuengling Center · Tampa, FL |
| 28 | Thu Feb 17 | vsE Carolina | L57-65 | 7-18 | .280 | - | | Yuengling Center · Tampa, FL |
| 29 | Sat Feb 19 | vsTulsa | L57-65 | 7-19 | .269 | - | | Yuengling Center · Tampa, FL |
| 30 | Wed Feb 23 | atE Carolina | L60-64 | 7-20 | .259 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 31 | Sat Feb 26 | atCincinnati | W56-54 | 8-20 | .286 | - | | Fifth Third Arena · Cincinnati, OH |
| 32 | Thu Mar 3 | vs Memphis | L64-73 | 8-21 | .276 | - | ESPNU | Yuengling Center · Tampa, FL |
| 33 | Sun Mar 6 | atTemple | L47-75 | 8-22 | .267 | - | | Liacouras Center · Philadelphia, PA |
| 34 | Thu Mar 10 | atUCF | L58-60 | 8-23 | .258 | - | ESPNU | Addition Financial Arena · Orlando, FL |
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