| 1 | Tue Nov 5 | vs C Arkansas | W88-50 | 1-0 | 1.000 | - | ESPN+ | Marriott Center · Provo, UT |
| 2 | Fri Nov 8 | vs UC Riverside | W86-80 | 2-0 | 1.000 | - | ESPN+ | Marriott Center · Provo, UT |
| 3 | Wed Nov 13 | vs Queens | W99-55 | 3-0 | 1.000 | - | ESPN+ | Marriott Center · Provo, UT |
| 4 | Sat Nov 16 | vs Idaho | W95-71 | 4-0 | 1.000 | - | ESPN+ | Marriott Center · Provo, UT |
| 5 | Sat Nov 23 | vs Miss Valley St | W87-43 | 5-0 | 1.000 | - | ESPN+ | Marriott Center · Provo, UT |
| 6 | Thu Nov 28 | at #23Ole Miss | L85-96 (OT) | 5-1 | .833 | - | FS1 | SJB Pavilion · Oxford, MS |
| 7 | Fri Nov 29 | vs NC State | W72-61 | 6-1 | .857 | - | | Marriott Center · Provo, UT |
| 8 | Tue Dec 3 | at Providence | L64-83 | 6-2 | .750 | - | FS1 | Amica Mutual Pavilion · Providence, RI |
| 9 | Wed Dec 11 | vs Fresno St | W95-67 | 7-2 | .778 | - | ESPN+ | Marriott Center · Provo, UT |
| 10 | Sat Dec 14 | vs Wyoming | W68-49 | 8-2 | .800 | - | ESPN+ | Marriott Center · Provo, UT |
| 11 | Fri Dec 20 | vs FAMU | W103-57 | 9-2 | .818 | - | ESPN+ | Marriott Center · Provo, UT |
| 12 | Tue Dec 31 | vs Arizona St | W76-56 | 10-2 | .833 | - | ESPN2 | Marriott Center · Provo, UT |
| 13 | Sat Jan 4 | at #14Houston | L55-86 | 10-3 | .769 | - | ESPN+ | Fertitta Center · Houston, TX |
| 14 | Tue Jan 7 | vs Texas Tech | L67-72 | 10-4 | .714 | - | ESPN+ | Marriott Center · Provo, UT |
| 15 | Sat Jan 11 | at TCU | L67-71 | 10-5 | .667 | - | ESPN2 | Ed and Rae Schollmaier Arena · Fort Worth, TX |
| 16 | Tue Jan 14 | vs Oklahoma St | W85-69 | 11-5 | .688 | - | ESPN+ | Marriott Center · Provo, UT |
| 17 | Sat Jan 18 | at Utah | L72-73 (OT) | 11-6 | .647 | - | ESPN+ | Jon M. Huntsman Center · Salt Lake City, UT |
| 18 | Tue Jan 21 | at Colorado | W83-67 | 12-6 | .667 | - | ESPNU | CU Events Center · Boulder, CO |
| 19 | Sat Jan 25 | vs Cincinnati | W80-52 | 13-6 | .684 | - | ESPN2 | Marriott Center · Provo, UT |
| 20 | Tue Jan 28 | vs Baylor | W93-89 (OT) | 14-6 | .700 | - | ESPN2 | Marriott Center · Provo, UT |
| 21 | Sat Feb 1 | at UCF | W81-75 | 15-6 | .714 | - | ESPN+ | Addition Financial Arena · Orlando, FL |
| 22 | Tue Feb 4 | vs #20Arizona | L74-85 | 15-7 | .682 | - | ESPN | Marriott Center · Provo, UT |
| 23 | Sat Feb 8 | atCincinnati | L66-84 | 15-8 | .652 | - | ESPN2 | Fifth Third Arena · Cincinnati, OH |
| 24 | Tue Feb 11 | at West Virginia | W73-69 | 16-8 | .667 | - | CBS | WVU Coliseum · Morgantown, WV |
| 25 | Sat Feb 15 | vs Kansas St | W80-65 | 17-8 | .680 | - | ESPN+ | Marriott Center · Provo, UT |
| 26 | Tue Feb 18 | vs #23Kansas | W91-57 | 18-8 | .692 | - | ESPN | Marriott Center · Provo, UT |
| 27 | Sat Feb 22 | at#19Arizona | W96-95 | 19-8 | .704 | - | ESPN | McKale Center · Tucson, AZ |
| 28 | Wed Feb 26 | atArizona St | W91-81 | 20-8 | .714 | #25 | ESPN+ | Desert Financial Arena · Tempe, AZ |
| 29 | Sat Mar 1 | vsWest Virginia | W77-56 | 21-8 | .724 | #25 | ESPN2 | Marriott Center · Provo, UT |
| 30 | Tue Mar 4 | at #10Iowa State | W88-85 (2OT) | 22-8 | .733 | #23 | ESPN2 | James H. Hilton Coliseum · Ames, IA |
| 31 | Sat Mar 8 | vsUtah | W85-74 | 23-8 | .742 | #23 | ESPNU | Marriott Center · Provo, UT |
| 32 | Thu Mar 13 | vs#12Iowa State | W96-92 | 24-8 | .750 | #17 | ESPN2 | Marriott Center · Provo, UT |
| 33 | Fri Mar 14 | at#2Houston | L54-74 | 24-9 | .727 | #17 | ESPN2 | Fertitta Center · Houston, TX |
| 34 | Thu Mar 20 | vs #11VCU | W80-71 | 25-9 | .735 | #6 | TNT | Marriott Center · Provo, UT |
| 35 | Sat Mar 22 | at #3Wisconsin | W91-89 | 26-9 | .743 | #6 | CBS | Kohl Center · Madison, WI |
