| 1 | Mon Nov 3 | vs Villanova | W71-66 | 1-0 | 1.000 | #8 | TNT | T-Mobile Arena · Las Vegas, NV |
| 2 | Sat Nov 8 | vsHoly Cross | W98-53 | 2-0 | 1.000 | #8 | ESPN+ | Marriott Center · Provo, UT |
| 3 | Tue Nov 11 | vsDelaware | W85-68 | 3-0 | 1.000 | #7 | CBSSN | Marriott Center · Provo, UT |
| 4 | Sat Nov 15 | at3UConn | L84-86 | 3-1 | .750 | #7 | FOX | Gampel Pavilion · Storrs, CT |
| 5 | Fri Nov 21 | vs23Wisconsin | W98-70 | 4-1 | .800 | #9 | Peacock | Delta Center · Salt Lake City, UT |
| 6 | Thu Nov 27 | atMiami | W72-62 | 5-1 | .833 | #9 | ESPN | Watsco Center · Coral Gables, FL |
| 7 | Fri Nov 28 | atDayton | W83-79 | 6-1 | .857 | #9 | ESPN | UD Arena · Dayton, OH |
| 8 | Wed Dec 3 | vsCA Baptist | W91-60 | 7-1 | .875 | #9 | ESPN+ | Delta Center · Salt Lake City, UT |
| 9 | Tue Dec 9 | vsClemson | W67-64 | 8-1 | .889 | #10 | ESPN | Marriott Center · Provo, UT |
| 10 | Sat Dec 13 | vsUC Riverside | W100-53 | 9-1 | .900 | #10 | ESPN+ | Marriott Center · Provo, UT |
| 11 | Tue Dec 16 | vsPacific | W93-57 | 10-1 | .909 | #10 | ESPN+ | Marriott Center · Provo, UT |
| 12 | Fri Dec 19 | vsAbilene Chrstn | W85-67 | 11-1 | .917 | #10 | TNT | Marriott Center · Provo, UT |
| 13 | Mon Dec 22 | vsE Washington | W109-81 | 12-1 | .923 | #10 | ESPN+ | Marriott Center · Provo, UT |
| 14 | Sat Jan 3 | atKansas St | W83-73 | 13-1 | .929 | #10 | CBS | Bramlage Coliseum · Manhattan, KS |
| 15 | Wed Jan 7 | vsArizona St | W104-76 | 14-1 | .933 | #9 | Peacock | Marriott Center · Provo, UT |
| 16 | Sat Jan 10 | atUtah | W89-84 | 15-1 | .938 | #9 | ESPN | Jon M. Huntsman Center · Salt Lake City, UT |
| 17 | Wed Jan 14 | vsTCU | W76-70 | 16-1 | .941 | #11 | ESPN2 | Marriott Center · Provo, UT |
| 18 | Sat Jan 17 | at15Texas Tech | L71-84 | 16-2 | .889 | #11 | ESPN | United Supermarkets Arena · Lubbock, TX |
| 19 | Sat Jan 24 | vsUtah | W91-78 | 17-2 | .895 | #13 | FOX | Marriott Center · Provo, UT |
| 20 | Mon Jan 26 | vs1Arizona | L83-86 | 17-3 | .850 | #13 | ESPN | Marriott Center · Provo, UT |
| 21 | Sat Jan 31 | at14Kansas | L82-90 | 17-4 | .810 | #13 | ESPN | Allen Fieldhouse · Lawrence, KS |
| 22 | Wed Feb 4 | atOklahoma St | L92-99 | 17-5 | .773 | #16 | FS1 | Gallagher-Iba Arena · Stillwater, OK |
| 23 | Sat Feb 7 | vs8Houston | L66-77 | 17-6 | .739 | #16 | ESPN | Marriott Center · Provo, UT |
| 24 | Tue Feb 10 | atBaylor | W99-94 | 18-6 | .750 | #22 | ESPN2 | Ferrell Center · Waco, TX |
| 25 | Sat Feb 14 | vsColorado | W90-86 (OT) | 19-6 | .760 | #22 | FS1 | Marriott Center · Provo, UT |
| 26 | Wed Feb 18 | at4Arizona | L68-75 | 19-7 | .731 | #23 | ESPN | McKale Center · Tucson, AZ |
| 27 | Sat Feb 21 | vs6Iowa State | W79-69 | 20-7 | .741 | #23 | ESPN | Marriott Center · Provo, UT |
| 28 | Tue Feb 24 | vsUCF | L84-97 | 20-8 | .714 | #19 | ESPN2 | Marriott Center · Provo, UT |
| 29 | Sat Feb 28 | atWest Virginia | L71-79 | 20-9 | .690 | #19 | FOX | WVU Coliseum · Morgantown, WV |
