| 1 | Mon Nov 7 | vs SE Missouri St | L61-64 | 0-1 | .000 | - | | Yuengling Center · Tampa, FL |
| 2 | Fri Nov 11 | at#15Auburn | L59-67 | 0-2 | .000 | - | | Neville Arena · Auburn, AL |
| 3 | Mon Nov 14 | vsStetson | L67-68 | 0-3 | .000 | - | | Yuengling Center · Tampa, FL |
| 4 | Thu Nov 17 | vsAustin Peay | L60-62 | 0-4 | .000 | - | | Yuengling Center · Tampa, FL |
| 5 | Mon Nov 21 | vsUAB | L65-80 | 0-5 | .000 | - | CBS | Yuengling Center · Tampa, FL |
| 6 | Tue Nov 22 | atSaint Joseph's | W75-62 | 1-5 | .167 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 7 | Fri Nov 25 | vsSt Francis BK | W75-60 | 2-5 | .286 | - | | Yuengling Center · Tampa, FL |
| 8 | Tue Nov 29 | vsUMass | L67-73 | 2-6 | .250 | - | | Yuengling Center · Tampa, FL |
| 9 | Fri Dec 2 | vsCharleston So | W79-59 | 3-6 | .333 | - | | Yuengling Center · Tampa, FL |
| 10 | Mon Dec 12 | atNorthern Iowa | W72-69 | 4-6 | .400 | - | | McLeod Center · Cedar Falls, IA |
| 11 | Fri Dec 16 | vsDartmouth | W59-55 | 5-6 | .455 | - | | Yuengling Center · Tampa, FL |
| 12 | Mon Dec 19 | vsHofstra | W77-70 | 6-6 | .500 | - | | Yuengling Center · Tampa, FL |
| 13 | Thu Dec 22 | vsNJIT | W92-73 | 7-6 | .538 | - | | Yuengling Center · Tampa, FL |
| 14 | Thu Dec 29 | atMemphis | L86-93 | 7-7 | .500 | - | | FedExForum · Memphis, TN |
| 15 | Wed Jan 4 | vsTemple | L64-68 | 7-8 | .467 | - | | Yuengling Center · Tampa, FL |
| 16 | Sun Jan 8 | vsWichita St | L66-70 | 7-9 | .438 | - | | Yuengling Center · Tampa, FL |
| 17 | Wed Jan 11 | at#1Houston | L77-83 | 7-10 | .412 | - | | Fertitta Center · Houston, TX |
| 18 | Sun Jan 15 | atE Carolina | W81-70 | 8-10 | .444 | - | ESPN2 | Williams Arena at Minges Coliseum · Greenville, NC |
| 19 | Wed Jan 18 | vsCincinnati | L69-85 | 8-11 | .421 | - | | Yuengling Center · Tampa, FL |
| 20 | Sat Jan 21 | vsUCF | W85-72 | 9-11 | .450 | - | ESPNU | Yuengling Center · Tampa, FL |
| 21 | Wed Jan 25 | atTemple | L76-79 (OT) | 9-12 | .429 | - | | Liacouras Center · Philadelphia, PA |
| 22 | Sun Jan 29 | atSMU | L80-82 | 9-13 | .409 | - | ESPNU | Moody Coliseum · Dallas, TX |
| 23 | Wed Feb 1 | vsE Carolina | W71-63 | 10-13 | .435 | - | ESPNU | Yuengling Center · Tampa, FL |
| 24 | Wed Feb 8 | vsMemphis | L81-99 | 10-14 | .417 | - | | Yuengling Center · Tampa, FL |
| 25 | Sat Feb 11 | atCincinnati | L65-84 | 10-15 | .400 | - | | Fifth Third Arena · Cincinnati, OH |
| 26 | Wed Feb 15 | atTulsa | W96-69 | 11-15 | .423 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 27 | Sat Feb 18 | vsTulane | L66-84 | 11-16 | .407 | - | ESPNU | Yuengling Center · Tampa, FL |
| 28 | Wed Feb 22 | atUCF | W82-75 | 12-16 | .429 | - | ESPNU | Addition Financial Arena · Orlando, FL |
| 29 | Sat Feb 25 | vsSMU | W71-67 | 13-16 | .448 | - | | Yuengling Center · Tampa, FL |
| 30 | Wed Mar 1 | vsTulsa | W72-56 | 14-16 | .467 | - | | Yuengling Center · Tampa, FL |
| 31 | Sun Mar 5 | atWichita St | L49-69 | 14-17 | .452 | - | ESPNU | Charles Koch Arena · Wichita, KS |
| 32 | Thu Mar 9 | vsE Carolina | L58-73 | 14-18 | .438 | - | ESPNU | Yuengling Center · Tampa, FL |
