| 1 | Mon Nov 3 | at Saint Louis | 8:00 PM | 19-15 | .559 | - | ESPN+ | Chaifetz Arena · St. Louis, MO |
| 2 | Fri Nov 7 | atMissouri | 8:00 PM | 22-12 | .647 | - | SECN+ | Mizzou Arena · Columbia, MO |
| 3 | Wed Nov 12 | vsTBD | TBD | 0-0 | .000 | - | ESPN+ | Show Me Center · Cape Girardeau, MO |
| 4 | Sat Nov 15 | vsSt Thomas (MN) | TBD | 24-10 | .706 | - | ESPN+ | Show Me Center · Cape Girardeau, MO |
| 5 | Tue Nov 18 | atIowa | TBD | 17-16 | .515 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 6 | Tue Nov 25 | atCal Poly | TBD | 16-19 | .457 | - | | J. Lawrence Walkup Skydome · Flagstaff, AZ |
| 7 | Wed Nov 26 | atN Arizona | 8:00 PM | 18-16 | .529 | - | ESPN+ | J. Lawrence Walkup Skydome · Flagstaff, AZ |
| 8 | Sat Nov 29 | vsLipscomb | 1:00 PM | 25-10 | .714 | - | ESPN+ | Show Me Center · Cape Girardeau, MO |
| 9 | Tue Dec 2 | vsTBD | TBD | 0-0 | .000 | - | | Show Me Center · Cape Girardeau, MO |
| 10 | Sat Dec 6 | atChattanooga | 3:00 PM | 29-9 | .763 | - | | McKenzie Arena · Chattanooga, TN |
| 11 | Sun Dec 14 | vsTBD | TBD | 0-0 | .000 | - | | Show Me Center · Cape Girardeau, MO |
| 12 | Thu Dec 18 | atTennessee Tech | TBD | 15-17 | .469 | - | | Hooper Eblen Center · Cookeville, TN |
| 13 | Sat Dec 20 | atTennessee St | 4:30 PM | 17-16 | .515 | - | | Gentry Center · Nashville, TN |
| 14 | Thu Jan 1 | vsE Illinois | TBD | 12-19 | .387 | - | | Show Me Center · Cape Girardeau, MO |
| 15 | Sat Jan 3 | vsW Illinois | 4:30 PM | 12-19 | .387 | - | | Show Me Center · Cape Girardeau, MO |
| 16 | Thu Jan 8 | atSo Indiana | 8:30 PM | 10-20 | .333 | - | | Screaming Eagles Arena · Evansville, IN |
| 17 | Sat Jan 10 | atMorehead St | TBD | 15-17 | .469 | - | | Ellis T. Johnson Arena · Morehead, KY |
| 18 | Thu Jan 15 | vsLindenwood | TBD | 16-17 | .485 | - | | Show Me Center · Cape Girardeau, MO |
| 19 | Sat Jan 17 | vsSIUE | TBD | 22-12 | .647 | - | | Show Me Center · Cape Girardeau, MO |
| 20 | Tue Jan 20 | vsUT Martin | 8:30 PM | 14-19 | .424 | - | | Show Me Center · Cape Girardeau, MO |
| 21 | Thu Jan 22 | vsLittle Rock | TBD | 19-14 | .576 | - | | Show Me Center · Cape Girardeau, MO |
| 22 | Thu Jan 29 | atW Illinois | 8:30 PM | 12-19 | .387 | - | | LeRoy A. Ufkes Court at Western Hall · Macomb, IL |
| 23 | Sat Jan 31 | atE Illinois | TBD | 12-19 | .387 | - | | Lantz Arena · Charleston, IL |
| 24 | Thu Feb 5 | vsMorehead St | TBD | 15-17 | .469 | - | | Show Me Center · Cape Girardeau, MO |
| 25 | Sat Feb 7 | vsSo Indiana | 4:45 PM | 10-20 | .333 | - | | Show Me Center · Cape Girardeau, MO |
| 26 | Thu Feb 12 | atSIUE | TBD | 22-12 | .647 | - | | First Community Arena at the Vadalabene Center · Edwardsville, IL |
| 27 | Sat Feb 14 | atLindenwood | TBD | 16-17 | .485 | - | | placeholder · sf, ca |
| 28 | Tue Feb 17 | atUT Martin | 8:30 PM | 14-19 | .424 | - | | Kathleen and Tom Elam Center · Martin, TN |
| 29 | Sat Feb 21 | atLittle Rock | TBD | 19-14 | .576 | - | | Jack Stephens Center · Little Rock, AR |
| 30 | Thu Feb 26 | vsTennessee St | 8:30 PM | 17-16 | .515 | - | | Show Me Center · Cape Girardeau, MO |
| 31 | Sat Feb 28 | vsTennessee Tech | TBD | 15-17 | .469 | - | | Show Me Center · Cape Girardeau, MO |
