| 1 | Mon Nov 4 | at DePaul | L78-80 (OT) | 0-1 | .000 | - | FS1 | Wintrust Arena · Chicago, IL |
| 2 | Thu Nov 7 | vs Bucknell | L69-75 (OT) | 0-2 | .000 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 3 | Mon Nov 11 | at Marshall | L63-77 | 0-3 | .000 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 4 | Wed Nov 13 | at Bellarmine | W71-69 | 1-3 | .250 | - | ESPN+ | Knights Hall · Louisville, KY |
| 5 | Sat Nov 16 | at Purdue FW | L74-93 | 1-4 | .200 | - | ESPN+ | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 6 | Fri Nov 22 | vs South Dakota | W92-83 | 2-4 | .333 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 7 | Mon Nov 25 | vs Indiana St | W87-77 | 3-4 | .429 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 8 | Mon Dec 2 | vs TBD | W104-46 | 4-4 | .500 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 9 | Sat Dec 7 | at S Illinois | L70-73 | 4-5 | .444 | - | ESPN+ | Banterra Center · Carbondale, IL |
| 10 | Sun Dec 15 | vsTBD | W91-56 | 5-5 | .500 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 11 | Thu Dec 19 | vs Tennessee St | W77-75 | 6-5 | .545 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 12 | Sat Dec 21 | vs UT Martin | L46-77 | 6-6 | .500 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 13 | Tue Dec 31 | vs Morehead St | L68-70 | 6-7 | .462 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 14 | Thu Jan 2 | at Tennessee Tech | L64-68 | 6-8 | .429 | - | ESPN+ | Hooper Eblen Center · Cookeville, TN |
| 15 | Thu Jan 9 | at SE Missouri St | L66-77 | 6-9 | .400 | - | ESPN+ | Show Me Center · Cape Girardeau, MO |
| 16 | Sun Jan 12 | at Little Rock | L58-78 | 6-10 | .375 | - | ESPN+ | Jack Stephens Center · Little Rock, AR |
| 17 | Thu Jan 16 | vs Lindenwood | W80-73 | 7-10 | .412 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 18 | Sat Jan 18 | vs W Illinois | W78-66 | 8-10 | .444 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 19 | Thu Jan 23 | at SIUE | L76-82 | 8-11 | .421 | - | ESPN+ | First Community Arena at the Vadalabene Center · Edwardsville, IL |
| 20 | Sat Jan 25 | at E Illinois | W64-60 | 9-11 | .450 | - | ESPN+ | Lantz Arena · Charleston, IL |
| 21 | Tue Jan 28 | atMorehead St | L65-66 | 9-12 | .429 | - | ESPN+ | Ellis T. Johnson Arena · Morehead, KY |
| 22 | Sat Feb 1 | vsTennessee Tech | L65-78 | 9-13 | .409 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 23 | Thu Feb 6 | vsLittle Rock | L56-74 | 9-14 | .391 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 24 | Sat Feb 8 | vsSE Missouri St | L74-79 | 9-15 | .375 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 25 | Thu Feb 13 | atW Illinois | L62-87 | 9-16 | .360 | - | ESPN+ | LeRoy A. Ufkes Court at Western Hall · Macomb, IL |
| 26 | Sat Feb 15 | atLindenwood | L78-81 (OT) | 9-17 | .346 | - | ESPN+ | placeholder · sf, ca |
| 27 | Thu Feb 20 | vsE Illinois | L54-63 | 9-18 | .333 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
