| 1 | Mon Nov 3 | at Charlotte | L76-92 | 0-1 | .000 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 2 | Thu Nov 6 | vsTBD | W104-73 | 1-1 | .500 | - | ESPN+ | Hulman Center · Terre Haute, IN |
| 3 | Mon Nov 10 | atSIUE | W64-55 | 2-1 | .667 | - | ESPN+ | First Community Arena at the Vadalabene Center · Edwardsville, IL |
| 4 | Fri Nov 14 | at4Duke | L62-100 | 2-2 | .500 | - | ACC Network | Cameron Indoor Stadium · Durham, NC |
| 5 | Wed Nov 19 | vsLouisiana Tech | W60-51 | 3-2 | .600 | - | ESPN+ | Hulman Center · Terre Haute, IN |
| 6 | Sat Nov 22 | vsBall State | W70-52 | 4-2 | .667 | - | ESPN+ | Hulman Center · Terre Haute, IN |
| 7 | Wed Nov 26 | atLouisiana Tech | L73-75 | 4-3 | .571 | - | ESPN+ | Thomas Assembly Center · Ruston, LA |
| 8 | Fri Nov 28 | atAlcorn St | L74-81 | 4-4 | .500 | - | | Hulman Center · Terre Haute, IN |
| 9 | Tue Dec 2 | vsTBD | W99-57 | 5-4 | .556 | - | ESPN+ | Hulman Center · Terre Haute, IN |
| 10 | Sun Dec 7 | vsSo Indiana | W77-55 | 6-4 | .600 | - | ESPN+ | Hulman Center · Terre Haute, IN |
| 11 | Sun Dec 14 | atMilwaukee | W70-68 | 7-4 | .636 | - | ESPN+ | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 12 | Thu Dec 18 | vsBradley | L99-108 (3OT) | 7-5 | .583 | - | ESPN+ | Hulman Center · Terre Haute, IN |
| 13 | Sun Dec 21 | atIllinois St | L65-85 | 7-6 | .538 | - | ESPN+ | Redbird Arena · Normal, IL |
| 14 | Mon Dec 29 | vsBelmont | W81-80 (OT) | 8-6 | .571 | - | ESPN+ | Hulman Center · Terre Haute, IN |
| 15 | Thu Jan 1 | atNorthern Iowa | L66-75 | 8-7 | .533 | - | ESPN+ | McLeod Center · Cedar Falls, IA |
| 16 | Sun Jan 4 | atDrake | L72-74 | 8-8 | .500 | - | ESPN+ | The Knapp Center · Des Moines, IA |
| 17 | Sat Jan 10 | vsEvansville | L69-72 | 8-9 | .471 | - | ESPN+ | Hulman Center · Terre Haute, IN |
| 18 | Wed Jan 14 | vsIllinois St | W94-89 | 9-9 | .500 | - | ESPN+ | Hulman Center · Terre Haute, IN |
| 19 | Sat Jan 17 | atMurray St | L81-85 | 9-10 | .474 | - | ESPN+ | CFSB Center · Murray, KY |
| 20 | Wed Jan 21 | atBradley | L68-75 | 9-11 | .450 | - | ESPN+ | Carver Arena · Peoria, IL |
| 21 | Sat Jan 24 | vsDrake | L62-76 | 9-12 | .429 | - | ESPN+ | Hulman Center · Terre Haute, IN |
| 22 | Tue Jan 27 | atUIC | L74-76 | 9-13 | .409 | - | ESPN+ | Credit Union 1 Arena · Chicago, IL |
| 23 | Sat Jan 31 | vsValparaiso | L72-76 (OT) | 9-14 | .391 | - | ESPN+ | Hulman Center · Terre Haute, IN |
| 24 | Tue Feb 3 | atEvansville | W84-63 | 10-14 | .417 | - | ESPN+ | Ford Center · Evansville, IN |
| 25 | Mon Feb 9 | vsS Illinois | L65-80 | 10-15 | .400 | - | ESPN+ | Hulman Center · Terre Haute, IN |
| 26 | Thu Feb 12 | vsMurray St | L72-74 | 10-16 | .385 | - | ESPN+ | Hulman Center · Terre Haute, IN |
| 27 | Sun Feb 15 | atValparaiso | L75-76 | 10-17 | .370 | - | ESPN+ | Athletics-Recreation Center · Valparaiso, IN |
| 28 | Wed Feb 18 | vsNorthern Iowa | L60-81 | 10-18 | .357 | - | ESPN+ | Hulman Center · Terre Haute, IN |
| 29 | Sat Feb 21 | atBelmont | L70-87 | 10-19 | .345 | - | ESPN+ | Curb Event Center Arena · Nashville, TN |
| 30 | Wed Feb 25 | atS Illinois | L55-66 | 10-20 | .333 | - | ESPN+ | Banterra Center · Carbondale, IL |
| 31 | Sun Mar 1 | vsUIC | W79-63 | 11-20 | .355 | - | ESPN+ | Hulman Center · Terre Haute, IN |
