| 1 | Mon Nov 6 | vs TBD | W90-60 | 1-0 | 1.000 | - | | Hulman Center · Terre Haute, IN |
| 2 | Fri Nov 10 | at#24Alabama | L80-102 | 1-1 | .500 | - | | Coleman Coliseum · Tuscaloosa, AL |
| 3 | Tue Nov 14 | vsIU Indy | W96-57 | 2-1 | .667 | - | | Hulman Center · Terre Haute, IN |
| 4 | Tue Nov 21 | atRice | W103-88 | 3-1 | .750 | - | | Tudor Fieldhouse · Houston, TX |
| 5 | Wed Nov 22 | vsPepperdine | W90-82 | 4-1 | .800 | - | | Hulman Center · Terre Haute, IN |
| 6 | Fri Nov 24 | atToledo | W76-74 | 5-1 | .833 | - | | Savage Arena · Toledo, OH |
| 7 | Tue Nov 28 | vsS Illinois | W77-48 | 6-1 | .857 | - | | Hulman Center · Terre Haute, IN |
| 8 | Sat Dec 2 | atBradley | W85-77 | 7-1 | .875 | - | ESPNU | Carver Arena · Peoria, IL |
| 9 | Tue Dec 5 | atN Illinois | W90-67 | 8-1 | .889 | - | | NIU Convocation Center · Dekalb, IL |
| 10 | Sat Dec 9 | vsSo Indiana | W98-54 | 9-1 | .900 | - | | Hulman Center · Terre Haute, IN |
| 11 | Sat Dec 16 | atBall State | W83-72 | 10-1 | .909 | - | | Worthen Arena · Muncie, IN |
| 12 | Tue Dec 19 | vsTennessee St | W90-69 | 11-1 | .917 | - | | Hulman Center · Terre Haute, IN |
| 13 | Sat Dec 30 | atMichigan St | L75-87 | 11-2 | .846 | - | FS1 | Breslin Center · East Lansing, MI |
| 14 | Wed Jan 3 | vsEvansville | W87-73 | 12-2 | .857 | - | | Hulman Center · Terre Haute, IN |
| 15 | Sun Jan 7 | atNorthern Iowa | W77-66 | 13-2 | .867 | - | | McLeod Center · Cedar Falls, IA |
| 16 | Wed Jan 10 | atDrake | L78-89 | 13-3 | .813 | - | | The Knapp Center · Des Moines, IA |
| 17 | Sat Jan 13 | vsBelmont | W94-64 | 14-3 | .824 | - | | Hulman Center · Terre Haute, IN |
| 18 | Tue Jan 16 | vsMissouri St | W88-66 | 15-3 | .833 | - | | Hulman Center · Terre Haute, IN |
| 19 | Sun Jan 21 | atMurray St | W72-63 | 16-3 | .842 | - | ESPN2 | CFSB Center · Murray, KY |
| 20 | Wed Jan 24 | atUIC | W89-83 | 17-3 | .850 | - | | Credit Union 1 Arena · Chicago, IL |
| 21 | Sat Jan 27 | vsBradley | W95-86 (OT) | 18-3 | .857 | - | ESPNU | Hulman Center · Terre Haute, IN |
| 22 | Wed Jan 31 | atBelmont | W78-72 | 19-3 | .864 | - | | Curb Event Center Arena · Nashville, TN |
| 23 | Sat Feb 3 | vsDrake | W75-67 | 20-3 | .870 | - | ESPN2 | Hulman Center · Terre Haute, IN |
| 24 | Wed Feb 7 | vsValparaiso | W101-61 | 21-3 | .875 | - | | Hulman Center · Terre Haute, IN |
| 25 | Sat Feb 10 | atMissouri St | W73-71 | 22-3 | .880 | - | | Great Southern Bank Arena · Springfield, MO |
| 26 | Tue Feb 13 | vsIllinois St | L67-80 | 22-4 | .846 | #23 | | Hulman Center · Terre Haute, IN |
| 27 | Sat Feb 17 | atS Illinois | L69-74 | 22-5 | .815 | #23 | | Banterra Center · Carbondale, IL |
| 28 | Wed Feb 21 | atValparaiso | W83-64 | 23-5 | .821 | - | | Athletics-Recreation Center · Valparaiso, IN |
| 29 | Sat Feb 24 | vsUIC | W88-73 | 24-5 | .828 | - | | Hulman Center · Terre Haute, IN |
| 30 | Wed Feb 28 | atEvansville | W85-67 | 25-5 | .833 | - | | Ford Center · Evansville, IN |
| 31 | Sun Mar 3 | vsMurray St | W89-77 | 26-5 | .839 | - | | Hulman Center · Terre Haute, IN |
| 32 | Fri Mar 8 | vsMissouri St | W75-59 | 27-5 | .844 | - | | Hulman Center · Terre Haute, IN |
| 33 | Sat Mar 9 | vsNorthern Iowa | W94-72 | 28-5 | .848 | - | CBS | Hulman Center · Terre Haute, IN |
| 34 | Sun Mar 10 | vsDrake | L80-84 | 28-6 | .824 | - | CBS | Hulman Center · Terre Haute, IN |
| 35 | Wed Mar 20 | vsSMU | W101-92 | 29-6 | .829 | - | | Hulman Center · Terre Haute, IN |
| 36 | Sun Mar 24 | vsMinnesota | W76-64 | 30-6 | .833 | - | ESPN2 | Hulman Center · Terre Haute, IN |
| 37 | Tue Mar 26 | vsCincinnati | W85-81 | 31-6 | .838 | - | ESPN | Hulman Center · Terre Haute, IN |
| 38 | Tue Apr 2 | vsUtah | W100-90 | 32-6 | .842 | - | ESPN | Hinkle Fieldhouse · Indianapolis, IN |
| 39 | Thu Apr 4 | atSeton Hall | L77-79 | 32-7 | .821 | - | ESPN | Hinkle Fieldhouse · Indianapolis, IN |
