| 1 | Wed Nov 5 | at Butler | L58-88 | 0-1 | .000 | - | ESPN+ | Hinkle Fieldhouse · Indianapolis, IN |
| 2 | Fri Nov 7 | vsVMI | L74-78 | 0-2 | .000 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 3 | Wed Nov 12 | atSouth Dakota | L74-89 | 0-3 | .000 | - | | Sanford Coyote Sports Center · Vermillion, SD |
| 4 | Sun Nov 16 | vsTBD | W91-74 | 1-3 | .250 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 5 | Thu Nov 20 | atIncarnate Word | L81-87 | 1-4 | .200 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 6 | Sat Nov 22 | atUIC | L73-84 | 1-5 | .167 | - | | Credit Union 1 Arena · Chicago, IL |
| 7 | Wed Nov 26 | atValparaiso | W64-56 | 2-5 | .286 | - | ESPN+ | Athletics-Recreation Center · Valparaiso, IN |
| 8 | Sat Nov 29 | vsTBD | W93-56 | 3-5 | .375 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 9 | Wed Dec 3 | atW Michigan | L74-88 | 3-6 | .333 | - | ESPN+ | University Arena (MI) · Kalamazoo, MI |
| 10 | Sun Dec 7 | atIndiana St | L55-77 | 3-7 | .300 | - | ESPN+ | Hulman Center · Terre Haute, IN |
| 12 | Thu Dec 18 | vsLittle Rock | L62-77 | 3-8 | .273 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 13 | Sat Dec 20 | vsMorehead St | L60-64 (OT) | 3-9 | .250 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 14 | Thu Jan 1 | atSIUE | L55-59 | 3-10 | .231 | - | ESPN+ | First Community Arena at the Vadalabene Center · Edwardsville, IL |
| 15 | Sat Jan 3 | atLindenwood | L80-83 | 3-11 | .214 | - | ESPN+ | placeholder · sf, ca |
| 16 | Thu Jan 8 | vsSE Missouri St | L76-84 | 3-12 | .200 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 17 | Sat Jan 10 | vsUT Martin | L56-73 | 3-13 | .188 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 18 | Thu Jan 15 | atTennessee Tech | W71-54 | 4-13 | .235 | - | ESPN+ | Hooper Eblen Center · Cookeville, TN |
| 19 | Sat Jan 17 | atTennessee St | L67-73 | 4-14 | .222 | - | ESPN+ | Gentry Center · Nashville, TN |
| 20 | Thu Jan 22 | vsE Illinois | L51-59 (OT) | 4-15 | .211 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 21 | Fri Jan 23 | vsW Illinois | W96-64 | 5-15 | .250 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 22 | Thu Jan 29 | vsLindenwood | L60-73 | 5-16 | .238 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 23 | Sat Jan 31 | vsSIUE | L46-58 | 5-17 | .227 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 24 | Thu Feb 5 | atUT Martin | L54-76 | 5-18 | .217 | - | ESPN+ | Kathleen and Tom Elam Center · Martin, TN |
| 25 | Sat Feb 7 | atSE Missouri St | L65-90 | 5-19 | .208 | - | ESPN+ | Show Me Center · Cape Girardeau, MO |
| 26 | Thu Feb 12 | vsTennessee St | L71-73 | 5-20 | .200 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 27 | Sat Feb 14 | vsTennessee Tech | L74-82 | 5-21 | .192 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 28 | Thu Feb 19 | atW Illinois | W77-70 | 6-21 | .222 | - | ESPN+ | LeRoy A. Ufkes Court at Western Hall · Macomb, IL |
| 29 | Sat Feb 21 | atE Illinois | W70-68 | 7-21 | .250 | - | ESPN+ | Lantz Arena · Charleston, IL |
| 30 | Tue Feb 24 | atMorehead St | L63-64 | 7-22 | .241 | - | ESPN+ | Ellis T. Johnson Arena · Morehead, KY |
| 31 | Sat Feb 28 | atLittle Rock | L70-89 | 7-23 | .233 | - | ESPN+ | Jack Stephens Center · Little Rock, AR |
