| 1 | Wed Nov 6 | at Vanderbilt | L65-83 | 0-1 | .000 | - | | Memorial Gymnasium (TN) · Nashville, TN |
| 2 | Sun Nov 10 | vs Purdue FW | W79-78 | 1-1 | .500 | - | | Show Me Center · Cape Girardeau, MO |
| 3 | Tue Nov 19 | vs The Citadel | L69-74 | 1-2 | .333 | - | | Show Me Center · Cape Girardeau, MO |
| 4 | Fri Nov 22 | vs TBD | W72-71 | 2-2 | .500 | - | | Show Me Center · Cape Girardeau, MO |
| 5 | Wed Nov 27 | vs Fullerton | L57-64 | 2-3 | .400 | - | | Show Me Center · Cape Girardeau, MO |
| 6 | Fri Nov 29 | at Santa Clara | L75-87 | 2-4 | .333 | - | | Leavey Center · Santa Clara, CA |
| 7 | Sat Nov 30 | at Denver | W66-51 | 3-4 | .429 | - | | Hamilton Gymnasium · Denver, CO |
| 8 | Thu Dec 5 | at Abilene Chrstn | L64-73 | 3-5 | .375 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 9 | Sat Dec 7 | at Drake | L73-78 | 3-6 | .333 | - | | The Knapp Center · Des Moines, IA |
| 10 | Sun Dec 15 | at Youngstown St | L50-65 | 3-7 | .300 | - | | Beeghly Center · Youngstown, OH |
| 11 | Tue Dec 17 | at #5Ohio State | L48-80 | 3-8 | .273 | - | BTN | Value City Arena · Columbus, OH |
| 12 | Sat Dec 21 | at S Illinois | L45-64 | 3-9 | .250 | - | | Banterra Center · Carbondale, IL |
| 13 | Sun Dec 29 | vsTBD | W74-59 | 4-9 | .308 | - | | Show Me Center · Cape Girardeau, MO |
| 14 | Thu Jan 2 | at Austin Peay | L63-78 | 4-10 | .286 | - | | Winfield Dunn Center · Clarksville, TN |
| 15 | Sat Jan 4 | at Murray St | L59-81 | 4-11 | .267 | - | | CFSB Center · Murray, KY |
| 16 | Thu Jan 9 | vs Belmont | L64-89 | 4-12 | .250 | - | | Show Me Center · Cape Girardeau, MO |
| 17 | Sat Jan 11 | vs Tennessee St | L73-75 | 4-13 | .235 | - | | Show Me Center · Cape Girardeau, MO |
| 18 | Thu Jan 16 | vsAustin Peay | L59-84 | 4-14 | .222 | - | | Show Me Center · Cape Girardeau, MO |
| 19 | Sat Jan 18 | vsMurray St | L91-96 (OT) | 4-15 | .211 | - | | Show Me Center · Cape Girardeau, MO |
| 20 | Thu Jan 23 | at SIUE | L65-84 | 4-16 | .200 | - | | First Community Arena at the Vadalabene Center · Edwardsville, IL |
| 21 | Sat Jan 25 | at E Illinois | L59-61 | 4-17 | .190 | - | | Lantz Arena · Charleston, IL |
| 22 | Thu Jan 30 | at Morehead St | L74-90 | 4-18 | .182 | - | | Ellis T. Johnson Arena · Morehead, KY |
| 23 | Sat Feb 1 | at E Kentucky | L57-70 | 4-19 | .174 | - | | McBrayer Arena · Richmond, KY |
| 24 | Thu Feb 6 | vs J'Ville St | W76-72 | 5-19 | .208 | - | | Show Me Center · Cape Girardeau, MO |
| 25 | Sat Feb 8 | vs Tennessee Tech | L60-62 | 5-20 | .200 | - | | Show Me Center · Cape Girardeau, MO |
| 26 | Thu Feb 13 | vs UT Martin | W74-72 | 6-20 | .231 | - | | Show Me Center · Cape Girardeau, MO |
| 27 | Sat Feb 15 | vsSIUE | W75-71 | 7-20 | .259 | - | | Show Me Center · Cape Girardeau, MO |
| 28 | Thu Feb 20 | atJ'Ville St | L58-65 | 7-21 | .250 | - | | Pete Mathews Coliseum · Jacksonville, AL |
| 29 | Sat Feb 22 | atTennessee Tech | L62-71 | 7-22 | .241 | - | | Hooper Eblen Center · Cookeville, TN |
| 30 | Thu Feb 27 | vsE Illinois | L70-72 | 7-23 | .233 | - | | Show Me Center · Cape Girardeau, MO |
| 31 | Sat Feb 29 | atUT Martin | L78-87 | 7-24 | .226 | - | | Kathleen and Tom Elam Center · Martin, TN |
