| 1 | Mon Nov 3 | at Loyola MD | W67-56 | 1-0 | 1.000 | - | | Reitz Arena · Baltimore, MD |
| 2 | Sat Nov 8 | at2Houston | L48-65 | 1-1 | .500 | - | ESPN+ | Fertitta Center · Houston, TX |
| 3 | Tue Nov 11 | vsTBD | W101-62 | 2-1 | .667 | - | | SECU Arena · Towson, MD |
| 4 | Fri Nov 14 | vsNorfolk St | W51-41 | 3-1 | .750 | - | | SECU Arena · Towson, MD |
| 5 | Tue Nov 18 | atJMU | L75-81 | 3-2 | .600 | - | ESPN+ | Atlantic Union Bank Center · Harrisonburg, VA |
| 6 | Mon Nov 24 | vsRhode Island | W62-55 | 4-2 | .667 | - | ESPN2 | SECU Arena · Towson, MD |
| 7 | Tue Nov 25 | atLiberty | W72-69 | 5-2 | .714 | - | ESPN2 | Liberty Arena · Lynchburg, VA |
| 8 | Wed Nov 26 | atUC San Diego | L73-87 | 5-3 | .625 | - | ESPN2 | University Credit Union Center · Davis, CA |
| 9 | Wed Dec 3 | vsCornell | W93-80 | 6-3 | .667 | - | | SECU Arena · Towson, MD |
| 10 | Sun Dec 7 | atUCF | L61-86 | 6-4 | .600 | - | ESPN+ | Addition Financial Arena · Orlando, FL |
| 11 | Tue Dec 16 | at17Kansas | L49-73 | 6-5 | .545 | - | ESPN2 | Allen Fieldhouse · Lawrence, KS |
| 12 | Fri Dec 19 | vsTBD | W107-60 | 7-5 | .583 | - | | SECU Arena · Towson, MD |
| 13 | Mon Dec 22 | vsSacred Heart | W72-47 | 8-5 | .615 | - | | SECU Arena · Towson, MD |
| 14 | Mon Dec 29 | atWilliam & Mary | L70-84 | 8-6 | .571 | - | | Kaplan Arena · Williamsburg, VA |
| 15 | Wed Dec 31 | atHampton | L62-63 | 8-7 | .533 | - | | Convocation Center (VA) · Hampton, VA |
| 16 | Sat Jan 3 | vsMonmouth | L48-62 | 8-8 | .500 | - | | SECU Arena · Towson, MD |
| 17 | Thu Jan 8 | vsHofstra | L67-78 | 8-9 | .471 | - | | SECU Arena · Towson, MD |
| 18 | Sat Jan 10 | atNortheastern | W87-78 | 9-9 | .500 | - | | Matthews Arena · Boston, MA |
| 19 | Thu Jan 15 | vsCharleston | W61-52 | 10-9 | .526 | - | CBSSN | SECU Arena · Towson, MD |
| 20 | Mon Jan 19 | vsDrexel | W59-58 | 11-9 | .550 | - | CBSSN | SECU Arena · Towson, MD |
| 21 | Thu Jan 22 | atElon | W72-59 | 12-9 | .571 | - | | Schar Center · Elon, NC |
| 22 | Sat Jan 24 | atNC A&T | L73-80 | 12-10 | .545 | - | | Corbett Sports Center · Greensboro, NC |
| 23 | Thu Jan 29 | vsUNC Wilmington | L73-82 | 12-11 | .522 | - | CBSSN | SECU Arena · Towson, MD |
| 24 | Sat Jan 31 | vsHampton | W82-50 | 13-11 | .542 | - | | SECU Arena · Towson, MD |
| 25 | Sat Feb 7 | atHofstra | L49-71 | 13-12 | .520 | - | CBSSN | David S. Mack Sports and Exhibition Complex · Hempstead, NY |
| 26 | Thu Feb 12 | vsStony Brook | W69-57 | 14-12 | .538 | - | | SECU Arena · Towson, MD |
| 27 | Sun Feb 15 | atMonmouth | L71-72 | 14-13 | .519 | - | CBSSN | OceanFirst Bank Center · West Long Branch, NJ |
| 28 | Sun Feb 22 | atDrexel | L62-68 | 14-14 | .500 | - | CBSSN | Daskalakis Athletic Center · Philadelphia, PA |
| 29 | Thu Feb 26 | vsElon | W58-56 | 15-14 | .517 | - | | SECU Arena · Towson, MD |
| 30 | Sat Feb 28 | vsCampbell | W71-67 | 16-14 | .533 | - | | SECU Arena · Towson, MD |
