| 1 | Mon Nov 4 | at Saint Mary's | L69-76 | 0-1 | .000 | - | ESPN+ | University Credit Union Pavilion · Moraga, CA |
| 2 | Fri Nov 8 | vsTBD | W89-34 | 1-1 | .500 | - | FloSports | SECU Arena · Towson, MD |
| 3 | Tue Nov 12 | atSouth Carolina | L54-80 | 1-2 | .333 | - | ESPN+ | Colonial Life Arena · Columbia, SC |
| 4 | Sat Nov 16 | vsJMU | W67-63 | 2-2 | .500 | - | FloSports | SECU Arena · Towson, MD |
| 5 | Wed Nov 20 | atNicholls | W70-64 | 3-2 | .600 | - | ESPN+ | David R. Stopher Gymnasium · Thibodaux, LA |
| 6 | Sun Nov 24 | atMorgan St | W64-60 | 4-2 | .667 | - | ESPN+ | Hill Field House · Baltimore, MD |
| 7 | Thu Nov 28 | vsKent State | L54-65 | 4-3 | .571 | - | ESPN+ | SECU Arena · Towson, MD |
| 8 | Fri Nov 29 | atKennesaw St | L63-67 (OT) | 4-4 | .500 | - | ESPN+ | KSU Convocation Center · Kennesaw, GA |
| 9 | Sat Nov 30 | vsUC Irvine | L60-67 | 4-5 | .444 | - | ESPN+ | SECU Arena · Towson, MD |
| 10 | Sat Dec 7 | vsUMBC | L71-84 | 4-6 | .400 | - | | SECU Arena · Towson, MD |
| 11 | Sat Dec 14 | atDuquesne | L47-65 | 4-7 | .364 | - | | UPMC Cooper Fieldhouse · Pittsburgh, PA |
| 12 | Tue Dec 17 | atRobert Morris | L67-68 | 4-8 | .333 | - | ESPN+ | UPMC Events Center · Moon Township, PA |
| 13 | Sun Dec 22 | vsBryant | W70-65 | 5-8 | .385 | - | | SECU Arena · Towson, MD |
| 14 | Thu Jan 2 | atUNC Wilmington | W65-61 (OT) | 6-8 | .429 | - | | Trask Coliseum · Wilmington, NC |
| 15 | Sat Jan 4 | atCharleston | L69-77 | 6-9 | .400 | - | | TD Arena · Charleston, SC |
| 16 | Thu Jan 9 | vsNortheastern | W80-73 | 7-9 | .438 | - | | SECU Arena · Towson, MD |
| 17 | Sat Jan 11 | atDrexel | W93-82 (OT) | 8-9 | .471 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 18 | Thu Jan 16 | vsHofstra | W65-60 | 9-9 | .500 | - | CBSSN | SECU Arena · Towson, MD |
| 19 | Sat Jan 18 | vsStony Brook | W53-49 | 10-9 | .526 | - | | SECU Arena · Towson, MD |
| 20 | Thu Jan 23 | vsNC A&T | W83-67 | 11-9 | .550 | - | | SECU Arena · Towson, MD |
| 21 | Mon Jan 27 | atNortheastern | W75-65 | 12-9 | .571 | - | CBSSN | Matthews Arena · Boston, MA |
| 22 | Thu Jan 30 | atDelaware | W76-66 | 13-9 | .591 | - | | Bob Carpenter Center · Newark, DE |
| 23 | Sat Feb 1 | vsDrexel | W55-54 | 14-9 | .609 | - | CBSSN | SECU Arena · Towson, MD |
| 24 | Thu Feb 6 | atStony Brook | W66-59 | 15-9 | .625 | - | | Island FCU Arena · Stony Brook, NY |
| 25 | Sat Feb 8 | atMonmouth | W73-67 | 16-9 | .640 | - | CBSSN | OceanFirst Bank Center · West Long Branch, NJ |
| 26 | Thu Feb 13 | vsDelaware | W75-70 | 17-9 | .654 | - | | SECU Arena · Towson, MD |
| 27 | Sat Feb 15 | vsMonmouth | W80-54 | 18-9 | .667 | - | | SECU Arena · Towson, MD |
| 28 | Thu Feb 20 | atElon | L63-69 | 18-10 | .643 | - | | Schar Center · Elon, NC |
| 29 | Sat Feb 22 | atCampbell | W76-67 | 19-10 | .655 | - | | John W. Pope Jr. Convocation Center · Buies Creek, NC |
| 30 | Thu Feb 27 | vsWilliam & Mary | W88-73 | 20-10 | .667 | - | | SECU Arena · Towson, MD |
| 31 | Sat Mar 1 | vsHampton | W75-72 | 21-10 | .677 | - | | SECU Arena · Towson, MD |
| 32 | Sun Mar 9 | vsDrexel | W82-76 | 22-10 | .688 | - | | SECU Arena · Towson, MD |
| 33 | Mon Mar 10 | vsDelaware | L72-82 | 22-11 | .667 | - | CBSSN | SECU Arena · Towson, MD |
