| 1 | Tue Nov 9 | at Albany | W77-56 | 1-0 | 1.000 | - | | SEFCU Arena · Albany, NY |
| 2 | Sat Nov 13 | vs Monmouth | L71-79 | 1-1 | .500 | - | | SECU Arena · Towson, MD |
| 3 | Tue Nov 16 | vs Hampton | W78-54 | 2-1 | .667 | - | | SECU Arena · Towson, MD |
| 4 | Fri Nov 19 | at Pitt | L59-63 | 2-2 | .500 | - | ACC Network | Petersen Events Center · Pittsburgh, PA |
| 5 | Tue Nov 23 | vs Penn | W76-61 | 3-2 | .600 | - | | SECU Arena · Towson, MD |
| 6 | Thu Nov 25 | vs San Francisco | L61-71 | 3-3 | .500 | - | FS1 | SECU Arena · Towson, MD |
| 7 | Fri Nov 26 | at New Mexico | W73-58 | 4-3 | .571 | - | FS2 | The Pit · Albuquerque, NM |
| 8 | Thu Dec 2 | vs Long Island | W72-63 | 5-3 | .625 | - | | SECU Arena · Towson, MD |
| 9 | Mon Dec 6 | at Kent State | W73-58 | 6-3 | .667 | - | | M.A.C. Center · Kent, OH |
| 10 | Wed Dec 8 | at #21Ohio State | L74-85 | 6-4 | .600 | - | ESPNU | Value City Arena · Columbus, OH |
| 11 | Sat Dec 11 | at Coppin St | W89-75 | 7-4 | .636 | - | | Physical Education Complex · Baltimore, MD |
| 12 | Tue Dec 14 | vs UNC Greensboro | W74-64 | 8-4 | .667 | - | | SECU Arena · Towson, MD |
| 13 | Wed Dec 22 | at Navy | W69-52 | 9-4 | .692 | - | | Alumni Hall (Navy) · Annapolis, MD |
| 14 | Fri Dec 31 | vs JMU | PPD | 25-9 | .735 | - | | SECU Arena · Towson, MD |
| 15 | Mon Jan 3 | at Drexel | L61-65 | 9-5 | .643 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 16 | Wed Jan 5 | at Delaware | PPD | 25-9 | .735 | - | | Bob Carpenter Center · Newark, DE |
| 17 | Sun Jan 9 | vs Northeastern | W70-67 | 10-5 | .667 | - | | SECU Arena · Towson, MD |
| 18 | Tue Jan 11 | vs Hofstra | W78-66 | 11-5 | .688 | - | CBS | SECU Arena · Towson, MD |
| 19 | Sat Jan 15 | at Elon | W59-54 | 12-5 | .706 | - | | Schar Center · Elon, NC |
| 20 | Mon Jan 17 | at William & Mary | W91-69 | 13-5 | .722 | - | | Kaplan Arena · Williamsburg, VA |
| 21 | Thu Jan 20 | vs Charleston | W74-67 | 14-5 | .737 | - | | SECU Arena · Towson, MD |
| 22 | Sat Jan 22 | vs UNC Wilmington | L77-81 (OT) | 14-6 | .700 | - | | SECU Arena · Towson, MD |
| 23 | Mon Jan 24 | atDelaware | W69-62 | 15-6 | .714 | - | | Bob Carpenter Center · Newark, DE |
| 25 | Sat Jan 29 | vsDrexel | W66-62 | 16-6 | .727 | - | | SECU Arena · Towson, MD |
| 26 | Thu Feb 3 | atHofstra | W78-68 | 17-6 | .739 | - | | David S. Mack Sports and Exhibition Complex · Hempstead, NY |
| 27 | Sat Feb 5 | atNortheastern | L53-58 | 17-7 | .708 | - | | Matthews Arena · Boston, MA |
| 28 | Thu Feb 10 | vsWilliam & Mary | W75-60 | 18-7 | .720 | - | CBS | SECU Arena · Towson, MD |
| 29 | Sat Feb 12 | vsElon | W86-50 | 19-7 | .731 | - | | SECU Arena · Towson, MD |
| 30 | Thu Feb 17 | atUNC Wilmington | W79-55 | 20-7 | .741 | - | CBS | Trask Coliseum · Wilmington, NC |
| 31 | Sat Feb 19 | atCharleston | W80-77 | 21-7 | .750 | - | | TD Arena · Charleston, SC |
| 32 | Wed Feb 23 | vsJMU | W84-65 | 22-7 | .759 | - | | SECU Arena · Towson, MD |
| 33 | Sat Feb 26 | atJMU | W95-59 | 23-7 | .767 | - | | Atlantic Union Bank Center · Harrisonburg, VA |
| 34 | Mon Feb 28 | vsDelaware | W69-57 | 24-7 | .774 | - | | SECU Arena · Towson, MD |
| 35 | Sun Mar 6 | vsNortheastern | W68-61 | 25-7 | .781 | - | | SECU Arena · Towson, MD |
| 36 | Mon Mar 7 | vsDelaware | L56-69 | 25-8 | .758 | - | CBS | SECU Arena · Towson, MD |
| 37 | Wed Mar 16 | at Wake Forest | L64-74 | 25-9 | .735 | - | | Lawrence Joel Veterans Memorial Coliseum · Winston-Salem, NC |
