| 1 | Mon Nov 4 | vs E Michigan | W64-44 | 1-0 | 1.000 | - | ESPN+ | Strahan Arena at the University Events Center · San Marcos, TX |
| 2 | Fri Nov 8 | vs TBD | W102-62 | 2-0 | 1.000 | - | ESPN+ | Strahan Arena at the University Events Center · San Marcos, TX |
| 3 | Tue Nov 12 | at TCU | L71-76 | 2-1 | .667 | - | ESPN+ | Ed and Rae Schollmaier Arena · Fort Worth, TX |
| 4 | Sat Nov 16 | at Abilene Chrstn | L60-72 | 2-2 | .500 | - | ESPN+ | Moody Coliseum (Abilene) · Abilene, TX |
| 5 | Thu Nov 21 | vs Bradley | L68-82 | 2-3 | .400 | - | ESPNU | Strahan Arena at the University Events Center · San Marcos, TX |
| 6 | Fri Nov 22 | at Princeton | W83-80 | 3-3 | .500 | - | ESPN+ | Jadwin Gymnasium · Princeton, NJ |
| 7 | Sun Nov 24 | vs Ohio | W74-65 | 4-3 | .571 | - | ESPNEWS | Strahan Arena at the University Events Center · San Marcos, TX |
| 8 | Sun Dec 1 | at Texas So | W72-59 | 5-3 | .625 | - | | H&PE Arena · Houston, TX |
| 9 | Wed Dec 4 | vsTBD | W97-49 | 6-3 | .667 | - | ESPN+ | Strahan Arena at the University Events Center · San Marcos, TX |
| 10 | Sun Dec 8 | vs Rice | W75-66 | 7-3 | .700 | - | ESPN+ | Strahan Arena at the University Events Center · San Marcos, TX |
| 11 | Sat Dec 14 | at FAU | L80-89 | 7-4 | .636 | - | ESPN+ | FAU Arena · Boca Raton, FL |
| 12 | Sat Dec 21 | vs Georgia So | W83-61 | 8-4 | .667 | - | ESPN+ | Strahan Arena at the University Events Center · San Marcos, TX |
| 13 | Sun Dec 29 | vs UT Arlington | L72-80 | 8-5 | .615 | - | ESPN+ | Strahan Arena at the University Events Center · San Marcos, TX |
| 14 | Thu Jan 2 | at Marshall | L71-77 | 8-6 | .571 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 15 | Sat Jan 4 | at Appalachian St | L61-72 | 8-7 | .533 | - | ESPN+ | Holmes Convocation Center · Boone, NC |
| 16 | Thu Jan 9 | at Troy | W74-73 | 9-7 | .563 | - | ESPN+ | Trojan Arena · Troy, AL |
| 17 | Sat Jan 11 | at Southern Miss | L88-92 (OT) | 9-8 | .529 | - | ESPN+ | Reed Green Coliseum · Hattiesburg, MS |
| 18 | Wed Jan 15 | vs Georgia St | W94-80 | 10-8 | .556 | - | ESPN+ | Strahan Arena at the University Events Center · San Marcos, TX |
| 19 | Sat Jan 18 | vsSouthern Miss | W85-82 (OT) | 11-8 | .579 | - | ESPN+ | Strahan Arena at the University Events Center · San Marcos, TX |
| 20 | Thu Jan 23 | at Louisiana | W89-74 | 12-8 | .600 | - | ESPN+ | Cajundome · Lafayette, LA |
| 21 | Sat Jan 25 | at Arkansas St | L65-80 | 12-9 | .571 | - | ESPN+ | First National Bank Arena · Jonesboro, AR |
| 22 | Thu Jan 30 | vsLouisiana | L61-70 | 12-10 | .545 | - | ESPN+ | Strahan Arena at the University Events Center · San Marcos, TX |
| 23 | Sat Feb 1 | vsArkansas St | L74-85 | 12-11 | .522 | - | ESPN+ | Strahan Arena at the University Events Center · San Marcos, TX |
| 24 | Wed Feb 5 | at Old Dominion | L64-75 | 12-12 | .500 | - | ESPN+ | Chartway Arena · Norfolk, VA |
| 25 | Sat Feb 8 | at C Michigan | L70-85 | 12-13 | .480 | - | ESPN+ | McGuirk Arena · Mount Pleasant, MI |
| 26 | Thu Feb 13 | at UL Monroe | W72-60 | 13-13 | .500 | - | ESPN+ | Fant-Ewing Coliseum · Monroe, LA |
| 27 | Sat Feb 15 | at South Alabama | L65-70 (OT) | 13-14 | .481 | - | ESPN+ | Mitchell Center · Mobile, AL |
| 28 | Wed Feb 19 | vsUL Monroe | W80-63 | 14-14 | .500 | - | ESPN+ | Strahan Arena at the University Events Center · San Marcos, TX |
| 29 | Sat Feb 22 | vsSouth Alabama | W93-92 (OT) | 15-14 | .517 | - | ESPN+ | Strahan Arena at the University Events Center · San Marcos, TX |
| 30 | Tue Feb 25 | vsTroy | L69-74 | 15-15 | .500 | - | ESPN+ | Strahan Arena at the University Events Center · San Marcos, TX |
| 31 | Fri Feb 28 | vs JMU | W102-93 (2OT) | 16-15 | .516 | - | ESPN+ | Strahan Arena at the University Events Center · San Marcos, TX |
| 32 | Thu Mar 6 | vsOld Dominion | L61-64 | 16-16 | .500 | - | ESPN+ | Strahan Arena at the University Events Center · San Marcos, TX |
