| 1 | Mon Nov 4 | at Utah | L59-100 | 0-1 | .000 | - | ESPN+ | Jon M. Huntsman Center · Salt Lake City, UT |
| 2 | Wed Nov 6 | at Utah State | L46-101 | 0-2 | .000 | - | | Dee Glen Smith Spectrum · Logan, UT |
| 3 | Sat Nov 9 | at TBD | L56-62 | 0-3 | .000 | - | | Convocation Center (LA) |
| 4 | Mon Nov 11 | at Tulane | L51-84 | 0-4 | .000 | - | ESPN+ | Devlin Fieldhouse · New Orleans, LA |
| 5 | Tue Nov 19 | at TCU | L48-71 | 0-5 | .000 | - | ESPN+ | Ed and Rae Schollmaier Arena · Fort Worth, TX |
| 6 | Fri Nov 22 | at Washington | L60-77 | 0-6 | .000 | - | B1G+ | Alaska Airlines Arena · Seattle, WA |
| 7 | Sun Nov 24 | at UC Riverside | L52-69 | 0-7 | .000 | - | ESPN+ | SRC Arena · Riverside, CA |
| 8 | Fri Nov 29 | at South Alabama | L65-74 (OT) | 0-8 | .000 | - | | Mitchell Center · Mobile, AL |
| 9 | Sun Dec 1 | at Maryland | L58-96 | 0-9 | .000 | - | BTN | XFINITY Center · College Park, MD |
| 10 | Wed Dec 4 | at Wichita St | L54-78 | 0-9 | .000 | - | ESPN+ | Charles Koch Arena · Wichita, KS |
| 11 | Sat Dec 7 | at #21Oklahoma | L78-94 | 0-10 | .000 | - | ESPN+ | Lloyd Noble Center · Norman, OK |
| 12 | Mon Dec 16 | at Rice | L75-77 | 0-12 | .000 | - | ESPN+ | Tudor Fieldhouse · Houston, TX |
| 13 | Sun Dec 22 | at UAB | L74-91 | 0-13 | .000 | - | ESPN+ | Bartow Arena · Birmingham, AL |
| 14 | Sat Jan 4 | vs Jackson St | L69-72 | 0-14 | .000 | - | | Davey L. Whitney Complex · Lorman, MS |
| 15 | Sat Jan 11 | vs Alabama A&M | W62-52 | 1-14 | .067 | - | | Davey L. Whitney Complex · Lorman, MS |
| 16 | Mon Jan 13 | vs Alabama St | W67-65 | 2-14 | .125 | - | | Davey L. Whitney Complex · Lorman, MS |
| 17 | Sat Jan 18 | at Texas So | L57-66 | 2-15 | .118 | - | | H&PE Arena · Houston, TX |
| 18 | Mon Jan 20 | at Prairie View | W78-70 | 3-15 | .167 | - | | William Nicks Building · Prairie View, TX |
| 19 | Sat Jan 25 | vs FAMU | L64-65 | 3-16 | .158 | - | | Davey L. Whitney Complex · Lorman, MS |
| 20 | Mon Jan 27 | vs Bethune | W70-61 | 4-16 | .200 | - | | Davey L. Whitney Complex · Lorman, MS |
| 21 | Sat Feb 1 | at Southern | L69-74 | 4-17 | .190 | - | | F. G. Clark Activity Center · Baton Rouge, LA |
| 22 | Mon Feb 3 | at Grambling | W60-53 | 5-17 | .227 | - | ESPNU | Fredrick C. Hobdy Assembly Center · Grambling, LA |
| 23 | Sat Feb 8 | vs AR-Pine Bluff | W79-60 | 6-17 | .261 | - | | Davey L. Whitney Complex · Lorman, MS |
| 24 | Mon Feb 10 | vs Miss Valley St | W86-39 | 7-17 | .292 | - | | Davey L. Whitney Complex · Lorman, MS |
| 25 | Sat Feb 15 | atBethune | W78-74 | 8-17 | .320 | - | | Moore Gymnasium (FL) · Daytona Beach, FL |
| 26 | Mon Feb 17 | atFAMU | L76-85 | 8-18 | .308 | - | | Al Lawson Center · Tallahassee, FL |
