| 1 | Thu Nov 7 | vs Robert Morris | W67-60 | 1-0 | 1.000 | - | | Cam Henderson Center · Huntington, WV |
| 2 | Sun Nov 10 | vs Toledo | L70-96 | 1-1 | .500 | - | | Cam Henderson Center · Huntington, WV |
| 3 | Fri Nov 15 | at Notre Dame | L64-74 | 1-2 | .333 | - | | Purcell Pavilion · South Bend, IN |
| 4 | Tue Nov 19 | vs Charleston | L66-76 | 1-3 | .250 | - | | Cam Henderson Center · Huntington, WV |
| 5 | Thu Nov 21 | vs Howard | W91-63 | 2-3 | .400 | - | | Cam Henderson Center · Huntington, WV |
| 6 | Fri Nov 29 | at #24Florida | L67-73 | 2-4 | .333 | - | SEC Network | Exactech Arena at Stephen C. O'Connell Center · Gainesville, FL |
| 7 | Wed Dec 4 | vs Akron | L73-85 | 2-5 | .286 | - | | Cam Henderson Center · Huntington, WV |
| 8 | Sun Dec 8 | atToledo | L72-82 | 2-6 | .250 | - | | Savage Arena · Toledo, OH |
| 9 | Wed Dec 11 | vs TBD | W86-50 | 3-6 | .333 | - | | Cam Henderson Center · Huntington, WV |
| 10 | Mon Dec 16 | at Morehead St | W89-62 | 4-6 | .400 | - | | Ellis T. Johnson Arena · Morehead, KY |
| 11 | Thu Dec 19 | vs E Kentucky | W90-72 | 5-6 | .455 | - | | Cam Henderson Center · Huntington, WV |
| 12 | Sun Dec 22 | at Northern Iowa | L80-88 | 5-7 | .417 | - | | McLeod Center · Cedar Falls, IA |
| 13 | Sun Dec 29 | at Duquesne | W83-61 | 6-7 | .462 | - | | UPMC Cooper Fieldhouse · Pittsburgh, PA |
| 14 | Thu Jan 2 | vs Rice | W89-69 | 7-7 | .500 | - | | Cam Henderson Center · Huntington, WV |
| 15 | Sat Jan 4 | vs North Texas | L64-67 | 7-8 | .467 | - | | Cam Henderson Center · Huntington, WV |
| 16 | Thu Jan 9 | at MTSU | W79-75 | 8-8 | .500 | - | | Murphy Center · Murfreesboro, TN |
| 17 | Sat Jan 11 | at UAB | L50-61 | 8-9 | .471 | - | | Bartow Arena · Birmingham, AL |
| 18 | Thu Jan 16 | vs Charlotte | L75-77 | 8-10 | .444 | - | | Cam Henderson Center · Huntington, WV |
| 19 | Sat Jan 18 | vs Old Dominion | W68-67 | 9-10 | .474 | - | | Cam Henderson Center · Huntington, WV |
| 20 | Wed Jan 22 | vs Western KY | L60-64 | 9-11 | .450 | - | | Cam Henderson Center · Huntington, WV |
| 21 | Sat Jan 25 | atWestern KY | L84-91 | 9-12 | .429 | - | | E. A. Diddle Arena · Bowling Green, KY |
| 22 | Thu Jan 30 | at FIU | W84-74 | 10-12 | .455 | - | | Ocean Bank Convocation Center · Miami, FL |
| 23 | Sat Feb 1 | at FAU | L73-91 | 10-13 | .435 | - | | FAU Arena · Boca Raton, FL |
| 24 | Thu Feb 6 | vs Southern Miss | W72-58 | 11-13 | .458 | - | | Cam Henderson Center · Huntington, WV |
| 25 | Sat Feb 8 | vs Louisiana Tech | W83-79 (OT) | 12-13 | .480 | - | | Cam Henderson Center · Huntington, WV |
| 26 | Thu Feb 13 | at UTSA | L63-72 | 12-14 | .462 | - | CBS | UTSA Convocation Center · San Antonio, TX |
| 27 | Sat Feb 15 | at UTEP | W71-61 | 13-14 | .481 | - | | Don Haskins Center · El Paso, TX |
| 28 | Sat Feb 22 | vsOld Dominion | W74-66 | 14-14 | .500 | - | | Cam Henderson Center · Huntington, WV |
| 29 | Thu Feb 27 | atUAB | L80-88 | 14-15 | .483 | - | | Bartow Arena · Birmingham, AL |
| 30 | Wed Mar 4 | vsFAU | W94-82 | 15-15 | .500 | - | | Cam Henderson Center · Huntington, WV |
| 31 | Sat Mar 7 | atUTSA | W82-77 | 16-15 | .516 | - | | UTSA Convocation Center · San Antonio, TX |
| 32 | Wed Mar 11 | vsUTEP | W86-78 | 17-15 | .531 | - | | Cam Henderson Center · Huntington, WV |
