| 1 | Mon Nov 4 | vs W Michigan | W60-56 | 1-0 | 1.000 | - | ESPN+ | The HTC Center · Conway, SC |
| 2 | Sat Nov 9 | at E Carolina | L59-63 | 1-1 | .500 | - | ESPN+ | Williams Arena at Minges Coliseum · Greenville, NC |
| 3 | Wed Nov 13 | at NC State | L70-82 | 1-2 | .333 | - | ESPN+ | PNC Arena · Raleigh, NC |
| 4 | Sun Nov 17 | vs J'Ville St | L53-71 | 1-3 | .250 | - | ESPN+ | The HTC Center · Conway, SC |
| 5 | Fri Nov 22 | vs IU Indy | W71-57 | 2-3 | .400 | - | | The HTC Center · Conway, SC |
| 6 | Sat Nov 23 | at Alabama A&M | L70-77 | 2-4 | .333 | - | | T.M. Elmore Gymnasium · Normal, AL |
| 7 | Sat Nov 30 | vs SC Upstate | W73-51 | 3-4 | .429 | - | ESPN+ | The HTC Center · Conway, SC |
| 8 | Wed Dec 4 | at Campbell | W58-57 | 4-4 | .500 | - | | John W. Pope Jr. Convocation Center · Buies Creek, NC |
| 9 | Sat Dec 7 | at Winthrop | L89-96 | 4-5 | .444 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
| 10 | Wed Dec 11 | vs TBD | W82-57 | 5-5 | .500 | - | ESPN+ | The HTC Center · Conway, SC |
| 11 | Tue Dec 17 | at NC A&T | W73-68 | 6-5 | .545 | - | | Corbett Sports Center · Greensboro, NC |
| 12 | Sat Dec 21 | at Arkansas St | L67-97 | 6-6 | .500 | - | ESPN+ | First National Bank Arena · Jonesboro, AR |
| 13 | Sun Dec 29 | vsTBD | W75-53 | 7-6 | .538 | - | ESPN+ | The HTC Center · Conway, SC |
| 14 | Thu Jan 2 | vs Louisiana | L68-71 | 7-7 | .500 | - | ESPN+ | The HTC Center · Conway, SC |
| 15 | Sat Jan 4 | vs UL Monroe | W70-51 | 8-7 | .533 | - | ESPN+ | The HTC Center · Conway, SC |
| 16 | Wed Jan 8 | at Appalachian St | L51-74 | 8-8 | .500 | - | ESPN+ | Holmes Convocation Center · Boone, NC |
| 17 | Sat Jan 11 | at Georgia St | L74-79 | 8-9 | .471 | - | ESPN+ | GSU Convocation Center · Atlanta, GA |
| 18 | Thu Jan 16 | vs Georgia So | L87-88 (OT) | 8-10 | .444 | - | ESPN+ | The HTC Center · Conway, SC |
| 19 | Sat Jan 18 | vs Marshall | L64-77 | 8-11 | .421 | - | ESPN+ | The HTC Center · Conway, SC |
| 20 | Thu Jan 23 | atGeorgia So | L58-85 | 8-12 | .400 | - | ESPN+ | W.S. Hanner Fieldhouse · Statesboro, GA |
| 21 | Sat Jan 25 | at Old Dominion | L52-74 | 8-13 | .381 | - | ESPN+ | Chartway Arena · Norfolk, VA |
| 22 | Thu Jan 30 | at JMU | L64-73 | 8-14 | .364 | - | ESPN+ | Atlantic Union Bank Center · Harrisonburg, VA |
| 23 | Sat Feb 1 | atMarshall | L62-67 | 8-15 | .348 | - | ESPN+ | Cam Henderson Center · Huntington, WV |
| 24 | Wed Feb 5 | vs South Alabama | L59-84 | 8-16 | .333 | - | ESPN+ | The HTC Center · Conway, SC |
| 25 | Sat Feb 8 | at Bowling Green | L53-67 | 8-17 | .320 | - | ESPN+ | Stroh Center · Bowling Green, OH |
| 26 | Thu Feb 13 | vsAppalachian St | L46-64 | 8-18 | .308 | - | ESPN+ | The HTC Center · Conway, SC |
| 27 | Sat Feb 15 | vsJMU | L73-74 | 8-19 | .296 | - | ESPN+ | The HTC Center · Conway, SC |
| 28 | Thu Feb 20 | at Southern Miss | W87-78 | 9-19 | .321 | - | ESPN+ | Reed Green Coliseum · Hattiesburg, MS |
| 29 | Sat Feb 22 | at Troy | L66-83 | 9-20 | .310 | - | ESPN+ | Trojan Arena · Troy, AL |
| 30 | Wed Feb 26 | vsGeorgia St | W80-74 | 10-20 | .333 | - | ESPN+ | The HTC Center · Conway, SC |
| 31 | Fri Feb 28 | vsOld Dominion | L59-61 | 10-21 | .323 | - | ESPN+ | The HTC Center · Conway, SC |
| 32 | Tue Mar 4 | atSouthern Miss | L63-66 | 10-22 | .313 | - | ESPN+ | Reed Green Coliseum · Hattiesburg, MS |
