| 3 | Fri Nov 14 | at TCU | 9:00 PM | 2-1 | .667 | #6 | ESPN2 | Ed and Rae Schollmaier Arena · Fort Worth, TX |
| 4 | Wed Nov 19 | vsMTSU | 6:30 PM | 3-0 | 1.000 | #6 | BTN | Crisler Center · Ann Arbor, MI |
| 5 | Mon Nov 24 | vsSDSU | 10:30 PM | 2-0 | 1.000 | #6 | truTV | Crisler Center · Ann Arbor, MI |
| 6 | Tue Nov 25 | at#22Auburn | 8:30 PM | 3-0 | 1.000 | #6 | TNT | Neville Arena · Auburn, AL |
| 7 | Sat Dec 6 | vsRutgers | 4:00 PM | 2-0 | 1.000 | #6 | | Crisler Center · Ann Arbor, MI |
| 8 | Tue Dec 9 | vsVillanova | 6:30 PM | 2-1 | .667 | #6 | | Crisler Center · Ann Arbor, MI |
| 9 | Sat Dec 13 | atMaryland | 8:00 PM | 2-1 | .667 | #6 | FOX | XFINITY Center · College Park, MD |
| 10 | Sun Dec 21 | vsLa Salle | 4:00 PM | 2-1 | .667 | #6 | | Crisler Center · Ann Arbor, MI |
| 11 | Mon Dec 29 | vsMcNeese | 7:00 PM | 2-1 | .667 | #6 | | Crisler Center · Ann Arbor, MI |
| 12 | Fri Jan 2 | vsUSC | 7:00 PM | 2-0 | 1.000 | #6 | | Crisler Center · Ann Arbor, MI |
| 13 | Tue Jan 6 | atPenn State | 7:00 PM | 3-0 | 1.000 | #6 | FS1 | Bryce Jordan Center · University Park, PA |
| 14 | Sat Jan 10 | vs#24Wisconsin | TBD | 3-0 | 1.000 | #6 | | Crisler Center · Ann Arbor, MI |
| 15 | Wed Jan 14 | atWashington | 10:30 PM | 2-1 | .667 | #6 | | Alaska Airlines Arena · Seattle, WA |
| 16 | Sat Jan 17 | atOregon | 4:00 PM | 3-0 | 1.000 | #6 | | Matthew Knight Arena · Eugene, OR |
| 17 | Tue Jan 20 | vsIndiana | 7:00 PM | 3-0 | 1.000 | #6 | | Crisler Center · Ann Arbor, MI |
| 18 | Fri Jan 23 | vsOhio State | 8:00 PM | 3-0 | 1.000 | #6 | | Crisler Center · Ann Arbor, MI |
| 19 | Tue Jan 27 | vsNebraska | 7:00 PM | 3-0 | 1.000 | #6 | Peacock | Crisler Center · Ann Arbor, MI |
| 20 | Fri Jan 30 | at#17Michigan St | 8:00 PM | 3-0 | 1.000 | #6 | | Breslin Center · East Lansing, MI |
| 21 | Thu Feb 5 | vsPenn State | 6:30 PM | 3-0 | 1.000 | #6 | FS1 | Crisler Center · Ann Arbor, MI |
| 22 | Sun Feb 8 | atOhio State | 1:00 PM | 3-0 | 1.000 | #6 | | Value City Arena · Columbus, OH |
| 23 | Wed Feb 11 | atNorthwestern | 8:30 PM | 3-0 | 1.000 | #6 | | Welsh-Ryan Arena · Evanston, IL |
| 24 | Sat Feb 14 | vs#15UCLA | 1:00 PM | 3-0 | 1.000 | #6 | | Crisler Center · Ann Arbor, MI |
| 25 | Tue Feb 17 | at#2Purdue | 6:30 PM | 3-0 | 1.000 | #6 | | Mackey Arena · West Lafayette, IN |
| 26 | Sat Feb 21 | at#4Duke | 6:30 PM | 3-0 | 1.000 | #6 | ESPN | Capital One Arena · Washington, D.C. |
| 27 | Tue Feb 24 | vsMinnesota | 8:30 PM | 2-1 | .667 | #6 | | Crisler Center · Ann Arbor, MI |
| 28 | Fri Feb 27 | at#14Illinois | 8:00 PM | 3-0 | 1.000 | #6 | | State Farm Center · Champaign, IL |
| 29 | Thu Mar 5 | atIowa | 8:00 PM | 2-0 | 1.000 | #6 | | Carver-Hawkeye Arena · Iowa City, IA |
| 30 | Sun Mar 8 | vs#17Michigan St | 5:30 PM | 3-0 | 1.000 | #6 | | Crisler Center · Ann Arbor, MI |
