| 8 | Sat Dec 6 | vs Rutgers | 4:00 PM | 5-4 | .556 | #3 | BTN | Crisler Center · Ann Arbor, MI |
| 9 | Tue Dec 9 | vsVillanova | 6:30 PM | 6-1 | .857 | #3 | FS1 | Crisler Center · Ann Arbor, MI |
| 10 | Sat Dec 13 | atMaryland | 8:00 PM | 6-3 | .667 | #3 | FOX | XFINITY Center · College Park, MD |
| 11 | Sun Dec 21 | vsLa Salle | 4:00 PM | 3-6 | .333 | #3 | Peacock | Crisler Center · Ann Arbor, MI |
| 12 | Mon Dec 29 | vsMcNeese | 7:00 PM | 6-2 | .750 | #3 | B1G+ | Crisler Center · Ann Arbor, MI |
| 13 | Fri Jan 2 | vs#24USC | 7:00 PM | 8-0 | 1.000 | #3 | Peacock | Crisler Center · Ann Arbor, MI |
| 14 | Tue Jan 6 | atPenn State | 7:00 PM | 8-1 | .889 | #3 | FS1 | Bryce Jordan Center · University Park, PA |
| 15 | Sat Jan 10 | vsWisconsin | TBD | 6-2 | .750 | #3 | | Crisler Center · Ann Arbor, MI |
| 16 | Wed Jan 14 | atWashington | 10:30 PM | 5-3 | .625 | #3 | | Alaska Airlines Arena · Seattle, WA |
| 17 | Sat Jan 17 | atOregon | 4:00 PM | 4-4 | .500 | #3 | | Matthew Knight Arena · Eugene, OR |
| 18 | Tue Jan 20 | vs#22Indiana | 7:00 PM | 7-1 | .875 | #3 | | Crisler Center · Ann Arbor, MI |
| 19 | Fri Jan 23 | vsOhio State | 8:00 PM | 6-1 | .857 | #3 | | Crisler Center · Ann Arbor, MI |
| 20 | Tue Jan 27 | vsNebraska | 7:00 PM | 8-0 | 1.000 | #3 | Peacock | Crisler Center · Ann Arbor, MI |
| 21 | Fri Jan 30 | at#7Michigan St | 8:00 PM | 8-0 | 1.000 | #3 | | Breslin Center · East Lansing, MI |
| 22 | Thu Feb 5 | vsPenn State | 6:30 PM | 8-1 | .889 | #3 | FS1 | Crisler Center · Ann Arbor, MI |
| 23 | Sun Feb 8 | atOhio State | 1:00 PM | 6-1 | .857 | #3 | | Value City Arena · Columbus, OH |
| 24 | Wed Feb 11 | atNorthwestern | 8:30 PM | 5-3 | .625 | #3 | | Welsh-Ryan Arena · Evanston, IL |
| 25 | Sat Feb 14 | vsUCLA | 1:00 PM | 6-2 | .750 | #3 | | Crisler Center · Ann Arbor, MI |
| 26 | Tue Feb 17 | at#1Purdue | 6:30 PM | 8-0 | 1.000 | #3 | | Mackey Arena · West Lafayette, IN |
| 27 | Sat Feb 21 | at#4Duke | 6:30 PM | 9-0 | 1.000 | #3 | ESPN | Capital One Arena · Washington, D.C. |
| 28 | Tue Feb 24 | vsMinnesota | 8:30 PM | 5-4 | .556 | #3 | | Crisler Center · Ann Arbor, MI |
| 29 | Fri Feb 27 | at#14Illinois | 8:00 PM | 6-2 | .750 | #3 | | State Farm Center · Champaign, IL |
| 30 | Thu Mar 5 | atIowa | 8:00 PM | 7-1 | .875 | #3 | | Carver-Hawkeye Arena · Iowa City, IA |
| 31 | Sun Mar 8 | vs#7Michigan St | 5:30 PM | 8-0 | 1.000 | #3 | | Crisler Center · Ann Arbor, MI |
