| 1 | Mon Nov 3 | vs Oakland | 8:30 PM | 16-18 | .471 | #7 | FS1 | Crisler Center · Ann Arbor, MI |
| 2 | Tue Nov 11 | vsWake Forest | TBD | 21-11 | .656 | #7 | | Crisler Center · Ann Arbor, MI |
| 3 | Fri Nov 14 | atTCU | 9:00 PM | 16-16 | .500 | #7 | ESPN2 | Ed and Rae Schollmaier Arena · Fort Worth, TX |
| 4 | Wed Nov 19 | vsMTSU | TBD | 22-12 | .647 | #7 | | Crisler Center · Ann Arbor, MI |
| 5 | Mon Nov 24 | vsSDSU | 10:30 PM | 21-10 | .677 | #7 | | Crisler Center · Ann Arbor, MI |
| 6 | Tue Nov 25 | at#20Auburn | 8:30 PM | 32-6 | .842 | #7 | | Neville Arena · Auburn, AL |
| 7 | Sat Dec 6 | vsRutgers | TBD | 15-17 | .469 | #7 | | Crisler Center · Ann Arbor, MI |
| 8 | Tue Dec 9 | vsVillanova | TBD | 21-15 | .583 | #7 | | Crisler Center · Ann Arbor, MI |
| 9 | Sat Dec 13 | atMaryland | TBD | 27-9 | .750 | #7 | | XFINITY Center · College Park, MD |
| 10 | Sun Dec 21 | vsLa Salle | 4:00 PM | 14-19 | .424 | #7 | | Crisler Center · Ann Arbor, MI |
| 11 | Mon Dec 29 | vsMcNeese | TBD | 28-7 | .800 | #7 | | Crisler Center · Ann Arbor, MI |
| 12 | Fri Jan 2 | vsUSC | 7:00 PM | 17-18 | .486 | #7 | | Crisler Center · Ann Arbor, MI |
| 13 | Tue Jan 6 | atPenn State | 7:00 PM | 16-15 | .516 | #7 | FS1 | Bryce Jordan Center · University Park, PA |
| 14 | Sat Jan 10 | vs#24Wisconsin | TBD | 27-10 | .730 | #7 | | Crisler Center · Ann Arbor, MI |
| 15 | Wed Jan 14 | atWashington | TBD | 13-18 | .419 | #7 | | Alaska Airlines Arena · Seattle, WA |
| 16 | Sat Jan 17 | atOregon | TBD | 25-10 | .714 | #7 | | Matthew Knight Arena · Eugene, OR |
| 17 | Tue Jan 20 | vsIndiana | TBD | 19-13 | .594 | #7 | | Crisler Center · Ann Arbor, MI |
| 18 | Fri Jan 23 | vsOhio State | TBD | 17-15 | .531 | #7 | | Crisler Center · Ann Arbor, MI |
| 19 | Tue Jan 27 | vsNebraska | 7:00 PM | 21-14 | .600 | #7 | Peacock | Crisler Center · Ann Arbor, MI |
| 20 | Fri Jan 30 | at#22Michigan St | TBD | 30-7 | .811 | #7 | | Breslin Center · East Lansing, MI |
| 21 | Thu Feb 5 | vsPenn State | 6:30 PM | 16-15 | .516 | #7 | FS1 | Crisler Center · Ann Arbor, MI |
| 22 | Sun Feb 8 | atOhio State | TBD | 17-15 | .531 | #7 | | Value City Arena · Columbus, OH |
| 23 | Wed Feb 11 | atNorthwestern | TBD | 17-16 | .515 | #7 | | Welsh-Ryan Arena · Evanston, IL |
| 24 | Sat Feb 14 | vs#12UCLA | 1:00 PM | 23-11 | .676 | #7 | | Crisler Center · Ann Arbor, MI |
| 25 | Tue Feb 17 | at#1Purdue | TBD | 24-12 | .667 | #7 | | Mackey Arena · West Lafayette, IN |
| 26 | Sat Feb 21 | at#6Duke | TBD | 35-4 | .897 | #7 | | Cameron Indoor Stadium · Durham, NC |
| 27 | Tue Feb 24 | vsMinnesota | TBD | 15-17 | .469 | #7 | | Crisler Center · Ann Arbor, MI |
| 28 | Fri Feb 27 | at#17Illinois | TBD | 22-13 | .629 | #7 | | State Farm Center · Champaign, IL |
| 29 | Thu Mar 5 | atIowa | TBD | 17-16 | .515 | #7 | | Carver-Hawkeye Arena · Iowa City, IA |
| 30 | Sun Mar 8 | vs#22Michigan St | TBD | 30-7 | .811 | #7 | | Crisler Center · Ann Arbor, MI |
