| 3 | Fri Nov 14 | vs MD-Eastern | 8:00 PM | 1-3 | .250 | #23 | Peacock | CHI Health Center Omaha · Omaha, NE |
| 4 | Wed Nov 19 | vsNorth Dakota | 8:00 PM | 1-3 | .250 | #23 | ESPN+ | CHI Health Center Omaha · Omaha, NE |
| 5 | Mon Nov 24 | atBaylor | 2:00 PM | 2-0 | 1.000 | #23 | truTV | Ferrell Center · Waco, TX |
| 6 | Tue Nov 25 | vs#16Iowa State | 2:00 PM | 3-0 | 1.000 | #23 | truTV | CHI Health Center Omaha · Omaha, NE |
| 7 | Tue Dec 2 | vsNicholls | 9:00 PM | 0-2 | .000 | #23 | | CHI Health Center Omaha · Omaha, NE |
| 8 | Sun Dec 7 | atNebraska | 5:00 PM | 3-0 | 1.000 | #23 | FS1 | Pinnacle Bank Arena · Lincoln, NE |
| 9 | Sat Dec 13 | vsKansas St | 3:00 PM | 2-0 | 1.000 | #23 | FOX | CHI Health Center Omaha · Omaha, NE |
| 10 | Wed Dec 17 | atXavier | 6:30 PM | 2-1 | .667 | #23 | | Cintas Center · Cincinnati, OH |
| 11 | Sat Dec 20 | vsMarquette | 8:30 PM | 2-1 | .667 | #23 | | CHI Health Center Omaha · Omaha, NE |
| 12 | Mon Dec 22 | vsUtah Tech | 8:00 PM | 2-2 | .500 | #23 | ESPN+ | CHI Health Center Omaha · Omaha, NE |
| 13 | Tue Dec 30 | vsButler | 9:00 PM | 3-0 | 1.000 | #23 | | CHI Health Center Omaha · Omaha, NE |
| 14 | Sun Jan 4 | atSeton Hall | 12:00 PM | 3-0 | 1.000 | #23 | | Prudential Center · Newark, NJ |
| 15 | Wed Jan 7 | atVillanova | 7:30 PM | 2-1 | .667 | #23 | | Finneran Pavilion · Villanova, PA |
| 16 | Sat Jan 10 | vs#13St John's | 2:00 PM | 1-1 | .500 | #23 | | CHI Health Center Omaha · Omaha, NE |
| 17 | Tue Jan 13 | vsGeorgetown | 9:00 PM | 2-0 | 1.000 | #23 | | CHI Health Center Omaha · Omaha, NE |
| 18 | Fri Jan 16 | atProvidence | 6:30 PM | 2-1 | .667 | #23 | | Amica Mutual Pavilion · Providence, RI |
| 19 | Wed Jan 21 | vsXavier | 7:00 PM | 2-1 | .667 | #23 | | CHI Health Center Omaha · Omaha, NE |
| 20 | Tue Jan 27 | atMarquette | 9:30 PM | 2-1 | .667 | #23 | | Fiserv Forum · Milwaukee, WI |
| 21 | Sat Jan 31 | vs#3UConn | 8:00 PM | 3-0 | 1.000 | #23 | | CHI Health Center Omaha · Omaha, NE |
| 22 | Wed Feb 4 | atGeorgetown | 7:30 PM | 2-0 | 1.000 | #23 | | Capital One Arena · Washington, D.C. |
| 23 | Sat Feb 7 | vsSeton Hall | 6:00 PM | 3-0 | 1.000 | #23 | | CHI Health Center Omaha · Omaha, NE |
| 24 | Wed Feb 11 | atDePaul | 9:00 PM | 2-1 | .667 | #23 | | Wintrust Arena · Chicago, IL |
| 25 | Sat Feb 14 | vsVillanova | 2:30 PM | 2-1 | .667 | #23 | | CHI Health Center Omaha · Omaha, NE |
| 26 | Wed Feb 18 | at#3UConn | 7:00 PM | 3-0 | 1.000 | #23 | | Gampel Pavilion · Storrs, CT |
| 27 | Sat Feb 21 | at#13St John's | 12:00 PM | 1-1 | .500 | #23 | | Carnesecca Arena · Queens, NY |
| 28 | Wed Feb 25 | vsDePaul | 9:00 PM | 2-1 | .667 | #23 | | CHI Health Center Omaha · Omaha, NE |
| 29 | Sat Feb 28 | vsProvidence | 5:30 PM | 2-1 | .667 | #23 | | CHI Health Center Omaha · Omaha, NE |
| 30 | Wed Mar 4 | atButler | 6:00 PM | 3-0 | 1.000 | #23 | | Hinkle Fieldhouse · Indianapolis, IN |
