| Mon Nov 25 | at South Carolina | 8:30 PM | 3-2 | .600 | Colonial Life Arena · Columbia, SC |
| Sun Dec 1 | vs SC State | 4:30 PM | 2-3 | .400 | Cintas Center · Cincinnati, OH |
| Thu Dec 5 | at TCU | 8:00 PM | 4-1 | .800 | Ed and Rae Schollmaier Arena · Fort Worth, TX |
| Tue Dec 10 | vs Morgan St | 7:00 PM | 3-3 | .500 | Cintas Center · Cincinnati, OH |
| Sat Dec 14 | at #18Cincinnati | 2:00 PM | 4-0 | 1.000 | Fifth Third Arena · Cincinnati, OH |
| Wed Dec 18 | at #2UConn | 7:00 PM | 4-0 | 1.000 | Gampel Pavilion · Storrs, CT |
| Sat Dec 21 | vs #15Marquette | 12:00 PM | 5-0 | 1.000 | Cintas Center · Cincinnati, OH |
| Tue Dec 31 | vs Seton Hall | 2:00 PM | 3-2 | .600 | Cintas Center · Cincinnati, OH |
| Fri Jan 3 | at Georgetown | 8:00 PM | 3-1 | .750 | Capital One Arena · Washington, D.C. |
| Tue Jan 7 | vs #22St John's | 6:30 PM | 4-1 | .800 | Cintas Center · Cincinnati, OH |
| Sat Jan 11 | at DePaul | 4:00 PM | 5-0 | 1.000 | Wintrust Arena · Chicago, IL |
| Tue Jan 14 | vs Villanova | 6:30 PM | 3-3 | .500 | Cintas Center · Cincinnati, OH |
| Sat Jan 18 | at#15Marquette | 2:00 PM | 5-0 | 1.000 | Fiserv Forum · Milwaukee, WI |
| Wed Jan 22 | at#22St John's | 7:00 PM | 4-1 | .800 | Carnesecca Arena · Queens, NY |
| Sat Jan 25 | vs#2UConn | 8:00 PM | 4-0 | 1.000 | Cintas Center · Cincinnati, OH |
| Wed Jan 29 | at #14Creighton | 8:00 PM | 4-0 | 1.000 | CHI Health Center Omaha · Omaha, NE |
| Tue Feb 4 | vsGeorgetown | 8:30 PM | 3-1 | .750 | Cintas Center · Cincinnati, OH |
| Sun Feb 9 | atVillanova | 12:00 PM | 3-3 | .500 | Finneran Pavilion · Villanova, PA |
| Wed Feb 12 | at Providence | 8:00 PM | 5-0 | 1.000 | Amica Mutual Pavilion · Providence, RI |
| Sat Feb 15 | vsDePaul | 12:00 PM | 5-0 | 1.000 | Cintas Center · Cincinnati, OH |
| Tue Feb 18 | vs Butler | 8:00 PM | 3-1 | .750 | Cintas Center · Cincinnati, OH |
| Sun Feb 23 | atSeton Hall | 2:00 PM | 3-2 | .600 | Prudential Center · Newark, NJ |
| Sat Mar 1 | vs#14Creighton | 4:30 PM | 4-0 | 1.000 | Cintas Center · Cincinnati, OH |
| Wed Mar 5 | atButler | 7:00 PM | 3-1 | .750 | Hinkle Fieldhouse · Indianapolis, IN |
| Sat Mar 8 | vsProvidence | 12:00 AM | 5-0 | 1.000 | Cintas Center · Cincinnati, OH |
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