| 1 | Mon Nov 4 | vs TBD | W98-62 | 1-0 | 1.000 | - | ESPN+ | Knott Arena · Emmitsburg, MD |
| 2 | Fri Nov 8 | at Maryland | L52-86 | 1-1 | .500 | - | BTN | XFINITY Center · College Park, MD |
| 3 | Wed Nov 13 | at Bucknell | W93-89 (2OT) | 2-1 | .667 | - | ESPN+ | Sojka Pavilion · Lewisburg, PA |
| 4 | Sat Nov 16 | vs St Francis PA | W66-58 | 3-1 | .750 | - | ESPN+ | Knott Arena · Emmitsburg, MD |
| 5 | Wed Nov 20 | at Georgetown | L51-79 | 3-2 | .600 | - | FS1 | Capital One Arena · Washington, D.C. |
| 6 | Sat Nov 23 | vs Delaware St | W76-66 | 4-2 | .667 | - | ESPN+ | Knott Arena · Emmitsburg, MD |
| 7 | Sat Nov 30 | at Howard | W79-75 | 5-2 | .714 | - | ESPN+ | Burr Gymnasium · Washington, D.C. |
| 8 | Fri Dec 6 | at Marist | L50-53 | 5-3 | .625 | - | ESPN+ | McCann Arena · Poughkeepsie, NY |
| 9 | Sun Dec 8 | vs Fairfield | W101-94 | 6-3 | .667 | - | ESPN+ | Knott Arena · Emmitsburg, MD |
| 10 | Sat Dec 14 | vs Loyola MD | L69-77 | 6-4 | .600 | - | ESPN+ | Knott Arena · Emmitsburg, MD |
| 11 | Wed Dec 18 | at Long Island | W80-72 | 7-4 | .636 | - | | Steinberg Wellness Center · Brooklyn, NY |
| 12 | Sat Dec 21 | at Miami | W78-74 (OT) | 8-4 | .667 | - | ESPN+ | Watsco Center · Coral Gables, FL |
| 13 | Sat Dec 28 | at George Mason | L56-64 | 8-5 | .615 | - | ESPN+ | EagleBank Arena · Fairfax, VA |
| 14 | Sun Jan 5 | vs Niagara | W68-62 | 9-5 | .643 | - | ESPN+ | Knott Arena · Emmitsburg, MD |
| 15 | Fri Jan 10 | at Manhattan | W75-66 | 10-5 | .667 | - | ESPN+ | Draddy Gymnasium · Riverdale, NY |
| 16 | Sun Jan 12 | vs Sacred Heart | W73-71 | 11-5 | .688 | - | ESPN+ | Knott Arena · Emmitsburg, MD |
| 17 | Thu Jan 16 | at Rider | L60-66 | 11-6 | .647 | - | ESPN+ | Alumni Gymnasium (Rider) · Lawrenceville, NJ |
| 18 | Sat Jan 18 | vs Quinnipiac | L57-91 | 11-7 | .611 | - | ESPN+ | Knott Arena · Emmitsburg, MD |
| 19 | Thu Jan 23 | at Siena | L68-82 | 11-8 | .579 | - | ESPN+ | MVP Arena · Albany, NY |
| 20 | Sat Jan 25 | vsManhattan | L64-74 | 11-9 | .550 | - | ESPN+ | Knott Arena · Emmitsburg, MD |
| 21 | Fri Jan 31 | at Merrimack | W66-58 | 12-9 | .571 | - | ESPN+ | placeholder · sf, ca |
| 22 | Sun Feb 2 | at Saint Peter's | W79-64 | 13-9 | .591 | - | ESPN+ | Yanitelli Center · Jersey City, NJ |
| 23 | Thu Feb 6 | vs Iona | L67-70 (OT) | 13-10 | .565 | - | ESPN+ | Knott Arena · Emmitsburg, MD |
| 24 | Fri Feb 14 | atNiagara | W84-83 | 14-10 | .583 | - | ESPN+ | Gallagher Center · Niagara Falls, NY |
| 25 | Sun Feb 16 | at Canisius | W73-66 | 15-10 | .600 | - | ESPN+ | Koessler Athletic Center · Buffalo, NY |
