| 1 | Mon Nov 4 | at Northwestern | L46-90 | 0-1 | .000 | - | Peacock | Welsh-Ryan Arena · Evanston, IL |
| 2 | Wed Nov 6 | at Georgetown | L77-85 | 0-2 | .000 | - | FS2 | Capital One Arena · Washington, D.C. |
| 3 | Tue Nov 12 | at Columbia | L75-76 | 0-3 | .000 | - | ESPN+ | Francis S. Levien Gymnasium · New York, NY |
| 4 | Fri Nov 15 | at UCLA | L45-85 | 0-4 | .000 | - | B1G+ | Pauley Pavilion · Los Angeles, CA |
| 5 | Wed Nov 20 | vs TBD | W100-53 | 1-4 | .200 | - | ESPN+ | Stabler Arena · Bethlehem, PA |
| 6 | Tue Nov 26 | at St Francis PA | L78-88 | 1-5 | .167 | - | | DeGol Arena · Loretto, PA |
| 7 | Sat Nov 30 | vs Marist | W74-69 | 2-5 | .286 | - | ESPN+ | Stabler Arena · Bethlehem, PA |
| 8 | Wed Dec 4 | vs Monmouth | W90-63 | 3-5 | .375 | - | ESPN+ | Stabler Arena · Bethlehem, PA |
| 9 | Sat Dec 7 | at Dayton | L62-86 | 3-6 | .333 | - | ESPN+ | UD Arena · Dayton, OH |
| 10 | Sat Dec 21 | at Long Island | W60-59 | 4-6 | .400 | - | | Steinberg Wellness Center · Brooklyn, NY |
| 11 | Sun Dec 29 | vsTBD | W87-67 | 5-6 | .455 | - | ESPN+ | Stabler Arena · Bethlehem, PA |
| 12 | Thu Jan 2 | vs Bucknell | W66-64 (OT) | 6-6 | .500 | - | ESPN+ | Stabler Arena · Bethlehem, PA |
| 13 | Sun Jan 5 | at Loyola MD | L74-80 | 6-7 | .462 | - | ESPN+ | Reitz Arena · Baltimore, MD |
| 14 | Wed Jan 8 | at Colgate | L62-67 | 6-8 | .429 | - | ESPN+ | Cotterell Court · Hamilton, NY |
| 15 | Sat Jan 11 | vs Army | L69-74 | 6-9 | .400 | - | ESPN+ | Stabler Arena · Bethlehem, PA |
| 16 | Wed Jan 15 | at Boston Univ | L58-63 | 6-10 | .375 | - | ESPN+ | Case Gym · Boston, MA |
| 17 | Sat Jan 18 | vsLoyola MD | L60-76 | 6-11 | .353 | - | ESPN+ | Stabler Arena · Bethlehem, PA |
| 18 | Wed Jan 22 | at American | L67-68 | 6-12 | .333 | - | ESPN+ | Bender Arena · Washington, D.C. |
| 19 | Sat Jan 25 | vs Lafayette | W86-47 | 7-12 | .368 | - | ESPN+ | Stabler Arena · Bethlehem, PA |
| 20 | Wed Jan 29 | vs Navy | L54-79 | 7-13 | .350 | - | ESPN+ | Stabler Arena · Bethlehem, PA |
| 21 | Sat Feb 1 | at Holy Cross | W69-67 | 8-13 | .381 | - | ESPN+ | Hart Center · Worcester, MA |
| 22 | Mon Feb 3 | vsColgate | W94-68 | 9-13 | .409 | - | CBS | Stabler Arena · Bethlehem, PA |
| 23 | Sat Feb 8 | vsAmerican | L75-78 (OT) | 9-14 | .391 | - | ESPN+ | Stabler Arena · Bethlehem, PA |
| 24 | Wed Feb 12 | atNavy | L60-63 | 9-15 | .375 | - | ESPN+ | Alumni Hall (Navy) · Annapolis, MD |
| 25 | Sat Feb 15 | vsHoly Cross | W72-60 | 10-15 | .400 | - | ESPN+ | Stabler Arena · Bethlehem, PA |
| 26 | Mon Feb 17 | atBucknell | L50-67 | 10-16 | .385 | - | CBS | Sojka Pavilion · Lewisburg, PA |
