| 1 | Sun Nov 29 | vs N Dakota St | W69-58 | 1-0 | 1.000 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 2 | Tue Dec 1 | vs Omaha | W94-67 | 2-0 | 1.000 | #9 | | CHI Health Center Omaha · Omaha, NE |
| 3 | Fri Dec 4 | vs Kennesaw St | W93-58 | 3-0 | 1.000 | #9 | | CHI Health Center Omaha · Omaha, NE |
| 4 | Tue Dec 8 | at Kansas | L72-73 | 3-1 | .750 | - | ESPN | Allen Fieldhouse · Lawrence, KS |
| 5 | Fri Dec 11 | vs Nebraska | W98-74 | 4-1 | .800 | #8 | BTN | CHI Health Center Omaha · Omaha, NE |
| 6 | Mon Dec 14 | vs Marquette | L84-89 | 4-2 | .667 | #9 | FS1 | CHI Health Center Omaha · Omaha, NE |
| 7 | Thu Dec 17 | at St John's | W94-76 | 5-2 | .714 | #9 | FS1 | Carnesecca Arena · Queens, NY |
| 8 | Sun Dec 20 | at UConn | W76-74 (OT) | 6-2 | .750 | #9 | FS1 | Gampel Pavilion · Storrs, CT |
| 9 | Wed Dec 23 | vs #22Xavier | W66-61 | 7-2 | .778 | #13 | FS1 | CHI Health Center Omaha · Omaha, NE |
| 10 | Sat Jan 2 | at Providence | W67-65 | 8-2 | .800 | #11 | FOX | Amica Mutual Pavilion · Providence, RI |
| 11 | Wed Jan 6 | vs Seton Hall | W89-53 | 9-2 | .818 | #7 | FS1 | CHI Health Center Omaha · Omaha, NE |
| 12 | Sat Jan 9 | vsSt John's | W97-79 | 10-2 | .833 | #7 | FS1 | CHI Health Center Omaha · Omaha, NE |
| 13 | Sat Jan 16 | at Butler | L66-70 (OT) | 10-3 | .769 | #8 | FS1 | Hinkle Fieldhouse · Indianapolis, IN |
| 14 | Wed Jan 20 | vsProvidence | L70-74 | 10-4 | .714 | #11 | FS1 | CHI Health Center Omaha · Omaha, NE |
| 15 | Sat Jan 23 | vs#23UConn | W74-66 | 11-4 | .733 | #11 | FOX | CHI Health Center Omaha · Omaha, NE |
| 16 | Wed Jan 27 | atSeton Hall | W85-81 | 12-4 | .750 | #17 | FS1 | Prudential Center · Newark, NJ |
| 17 | Sat Jan 30 | at DePaul | W69-62 | 13-4 | .765 | #17 | CBS | Wintrust Arena · Chicago, IL |
| 18 | Wed Feb 3 | vs Georgetown | L79-86 | 13-5 | .722 | #15 | FS1 | CHI Health Center Omaha · Omaha, NE |
| 19 | Sat Feb 6 | atMarquette | W71-68 | 14-5 | .737 | #15 | | Fiserv Forum · Milwaukee, WI |
| 20 | Tue Feb 9 | atGeorgetown | W63-48 | 15-5 | .750 | #19 | CBS | Capital One Arena · Washington, D.C. |
| 21 | Sat Feb 13 | vs #5Villanova | W86-70 | 16-5 | .762 | #19 | FOX | CHI Health Center Omaha · Omaha, NE |
| 22 | Wed Feb 24 | vsDePaul | W77-53 | 17-5 | .773 | #13 | CBS | CHI Health Center Omaha · Omaha, NE |
| 23 | Sat Feb 27 | atXavier | L69-77 | 17-6 | .739 | #13 | FOX | Cintas Center · Cincinnati, OH |
| 24 | Wed Mar 3 | at#10Villanova | L60-72 | 17-7 | .708 | #14 | FS1 | Finneran Pavilion · Villanova, PA |
| 25 | Sat Mar 6 | vsButler | W93-73 | 18-7 | .720 | - | FOX | CHI Health Center Omaha · Omaha, NE |
| 26 | Thu Mar 11 | vsButler | W87-56 | 19-7 | .731 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 27 | Fri Mar 12 | vsUConn | W59-56 | 20-7 | .741 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 28 | Sat Mar 13 | vsGeorgetown | L48-73 | 20-8 | .714 | - | FOX | CHI Health Center Omaha · Omaha, NE |
| 29 | Sat Mar 20 | vs #12UCSB | W63-62 | 21-8 | .724 | #5 | truTV | CHI Health Center Omaha · Omaha, NE |
| 30 | Mon Mar 22 | vs #13Ohio | W72-58 | 22-8 | .733 | #5 | TNT | CHI Health Center Omaha · Omaha, NE |
| 31 | Sun Mar 28 | at #1Gonzaga | L65-83 | 22-9 | .710 | #5 | CBS | McCarthey Athletic Center · Spokane, WA |
