| 1 | Tue Nov 9 | vs AR-Pine Bluff | W90-77 | 1-0 | 1.000 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 2 | Thu Nov 11 | vsKennesaw St | W51-44 | 2-0 | 1.000 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 3 | Tue Nov 16 | atNebraska | W77-69 | 3-0 | 1.000 | - | FS1 | Pinnacle Bank Arena · Lincoln, NE |
| 4 | Fri Nov 19 | vsBrown | W78-57 | 4-0 | 1.000 | - | | CHI Health Center Omaha · Omaha, NE |
| 5 | Sun Nov 21 | vsColorado St | L81-95 | 4-1 | .800 | - | | CHI Health Center Omaha · Omaha, NE |
| 6 | Mon Nov 22 | atS Illinois | W66-64 | 5-1 | .833 | - | | Banterra Center · Carbondale, IL |
| 7 | Sat Nov 27 | vsSIUE | W70-65 | 6-1 | .857 | - | FS2 | CHI Health Center Omaha · Omaha, NE |
| 8 | Tue Nov 30 | vsN Dakota St | W80-55 | 7-1 | .875 | - | FS2 | CHI Health Center Omaha · Omaha, NE |
| 9 | Sat Dec 4 | vsIowa State | L58-64 | 7-2 | .778 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 10 | Sat Dec 11 | vs24BYU | W83-71 | 8-2 | .800 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 11 | Tue Dec 14 | vsArizona St | L57-58 | 8-3 | .727 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 12 | Fri Dec 17 | vs9Villanova | W79-59 | 9-3 | .750 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 13 | Tue Dec 28 | vsGeorgetown | PPD | 23-12 | .657 | - | | CHI Health Center Omaha · Omaha, NE |
| 14 | Sat Jan 1 | atMarquette | W75-69 (2OT) | 10-3 | .769 | - | FS1 | Fiserv Forum · Milwaukee, WI |
| 15 | Wed Jan 5 | at19Villanova | L41-75 | 10-4 | .714 | - | FS1 | Finneran Pavilion · Villanova, PA |
| 17 | Sat Jan 15 | at17Xavier | L73-80 | 10-5 | .667 | - | FOX | Cintas Center · Cincinnati, OH |
| 18 | Wed Jan 19 | vsSt John's | W87-64 | 11-5 | .688 | - | | CHI Health Center Omaha · Omaha, NE |
| 19 | Sat Jan 22 | vsDePaul | W60-47 | 12-5 | .706 | - | CBSSN | CHI Health Center Omaha · Omaha, NE |
| 20 | Wed Jan 26 | atButler | L55-72 | 12-6 | .667 | - | FS1 | Hinkle Fieldhouse · Indianapolis, IN |
| 21 | Sat Jan 29 | vs21Xavier | L64-74 | 12-7 | .632 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 22 | Tue Feb 1 | at17UConn | W59-55 | 13-7 | .650 | - | FS1 | Gampel Pavilion · Storrs, CT |
| 23 | Fri Feb 4 | atSeton Hall | L55-74 | 13-8 | .619 | - | FS1 | Prudential Center · Newark, NJ |
| 24 | Tue Feb 8 | vsButler | W54-52 | 14-8 | .636 | - | CBSSN | CHI Health Center Omaha · Omaha, NE |
| 25 | Sat Feb 12 | atGeorgetown | W80-66 | 15-8 | .652 | - | FS1 | Capital One Arena · Washington, D.C. |
| 26 | Mon Feb 14 | vsGeorgetown | W88-77 | 16-8 | .667 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 27 | Thu Feb 17 | atDePaul | W71-59 | 17-8 | .680 | - | CBSSN | Wintrust Arena · Chicago, IL |
| 28 | Sun Feb 20 | vsMarquette | W83-82 | 18-8 | .692 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 29 | Wed Feb 23 | atSt John's | W81-78 | 19-8 | .704 | - | FS1 | Carnesecca Arena · Queens, NY |
| 30 | Sat Feb 26 | at11Providence | L51-72 | 19-9 | .679 | - | FS1 | Amica Mutual Pavilion · Providence, RI |
| 31 | Wed Mar 2 | vs18UConn | W64-62 | 20-9 | .690 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 32 | Sat Mar 5 | vsSeton Hall | L60-65 | 20-10 | .667 | - | FOX | CHI Health Center Omaha · Omaha, NE |
| 33 | Thu Mar 10 | vsMarquette | W74-63 | 21-10 | .677 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 34 | Fri Mar 11 | atProvidence | W85-58 | 22-10 | .688 | - | FS1 | Amica Mutual Pavilion · Providence, RI |
| 35 | Sat Mar 12 | atVillanova | L48-54 | 22-11 | .667 | - | FOX | Finneran Pavilion · Villanova, PA |
| 35 | Thu Mar 17 | at8SDSU | W72-69 (OT) | 23-11 | .676 | #9 | truTV | Viejas Arena · San Diego, CA |
| 36 | Sat Mar 19 | at1Kansas | L72-79 | 23-12 | .657 | #9 | CBS | Allen Fieldhouse · Lawrence, KS |
