| 1 | Mon Nov 7 | vs TBD | W74-47 | 1-0 | 1.000 | - | | UTSA Convocation Center · San Antonio, TX |
| 2 | Fri Nov 11 | at Texas A&M-CC | L55-75 | 1-1 | .500 | - | | American Bank Center · Corpus Christi, TX |
| 3 | Mon Nov 14 | vsTBD | W66-59 | 2-1 | .667 | - | | UTSA Convocation Center · San Antonio, TX |
| 4 | Thu Nov 17 | vs Texas St | W61-56 | 3-1 | .750 | - | | UTSA Convocation Center · San Antonio, TX |
| 5 | Tue Nov 22 | vs Prairie View | W82-75 | 4-1 | .800 | - | | UTSA Convocation Center · San Antonio, TX |
| 6 | Fri Nov 25 | vs Grambling | L55-75 | 4-2 | .667 | - | | UTSA Convocation Center · San Antonio, TX |
| 7 | Sun Nov 27 | vs Dartmouth | L77-78 (OT) | 4-3 | .571 | - | | UTSA Convocation Center · San Antonio, TX |
| 8 | Mon Nov 28 | vs Incarnate Word | W68-62 | 5-3 | .625 | - | | UTSA Convocation Center · San Antonio, TX |
| 9 | Sat Dec 10 | at New Mexico | L76-94 | 5-4 | .556 | - | | The Pit · Albuquerque, NM |
| 10 | Tue Dec 13 | at Utah | L70-91 | 5-5 | .500 | - | | Jon M. Huntsman Center · Salt Lake City, UT |
| 11 | Sun Dec 18 | vs Bethune | W90-69 | 6-5 | .545 | - | | UTSA Convocation Center · San Antonio, TX |
| 12 | Thu Dec 22 | vs North Texas | L54-78 | 6-6 | .500 | - | | UTSA Convocation Center · San Antonio, TX |
| 13 | Thu Dec 29 | at Louisiana Tech | L69-91 | 6-7 | .462 | - | | Thomas Assembly Center · Ruston, LA |
| 14 | Sat Dec 31 | at UAB | L67-90 | 6-8 | .429 | - | | Bartow Arena · Birmingham, AL |
| 15 | Thu Jan 5 | vs MTSU | W75-72 | 7-8 | .467 | - | | UTSA Convocation Center · San Antonio, TX |
| 16 | Sat Jan 7 | vs Western KY | L64-74 | 7-9 | .438 | - | | UTSA Convocation Center · San Antonio, TX |
| 17 | Wed Jan 11 | at UTEP | L57-69 | 7-10 | .412 | - | | Don Haskins Center · El Paso, TX |
| 18 | Sat Jan 14 | at Charlotte | L54-72 | 7-11 | .389 | - | | Dale F. Halton Arena · Charlotte, NC |
| 19 | Mon Jan 16 | vs Rice | L81-88 (OT) | 7-12 | .368 | - | | UTSA Convocation Center · San Antonio, TX |
| 20 | Thu Jan 19 | vs #24FAU | L64-83 | 7-13 | .350 | - | | UTSA Convocation Center · San Antonio, TX |
| 21 | Sat Jan 21 | vs FIU | L72-77 | 7-14 | .333 | - | | UTSA Convocation Center · San Antonio, TX |
| 22 | Thu Jan 26 | atNorth Texas | L59-63 | 7-15 | .318 | - | ESPNU | The Super Pit · Denton, TX |
| 23 | Sat Jan 28 | vsLouisiana Tech | L55-66 | 7-16 | .304 | - | | UTSA Convocation Center · San Antonio, TX |
| 24 | Thu Feb 2 | atWestern KY | L74-81 | 7-17 | .292 | - | | E. A. Diddle Arena · Bowling Green, KY |
| 25 | Sat Feb 4 | atMTSU | L60-84 | 7-18 | .280 | - | | Murphy Center · Murfreesboro, TN |
| 26 | Sat Feb 11 | vsUTEP | L66-77 | 7-19 | .269 | - | | UTSA Convocation Center · San Antonio, TX |
| 27 | Thu Feb 16 | atRice | W84-79 | 8-19 | .296 | - | | Tudor Fieldhouse · Houston, TX |
| 28 | Sat Feb 18 | vsUAB | L78-83 | 8-20 | .286 | - | | UTSA Convocation Center · San Antonio, TX |
| 29 | Thu Feb 23 | atFAU | L66-106 | 8-21 | .276 | - | | FAU Arena · Boca Raton, FL |
| 30 | Sat Feb 25 | atFIU | W95-91 | 9-21 | .300 | - | | Ocean Bank Convocation Center · Miami, FL |
| 31 | Thu Mar 2 | vsCharlotte | W78-73 | 10-21 | .323 | - | | UTSA Convocation Center · San Antonio, TX |
| 32 | Wed Mar 8 | atRice | L71-72 | 10-22 | .313 | - | | Tudor Fieldhouse · Houston, TX |
