| 1 | Mon Nov 6 | vs C Arkansas | W70-53 | 1-0 | 1.000 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 2 | Sat Nov 11 | vsIncarnate Word | W85-71 | 2-0 | 1.000 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 3 | Thu Nov 16 | vsJackson St | W72-52 | 3-0 | 1.000 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 4 | Mon Nov 20 | vsSC State | W90-70 | 4-0 | 1.000 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 5 | Sat Nov 25 | atLittle Rock | L82-84 (OT) | 4-1 | .800 | - | | Jack Stephens Center · Little Rock, AR |
| 6 | Sat Dec 2 | atOral Roberts | L70-79 | 4-2 | .667 | - | | Mabee Center · Tulsa, OK |
| 7 | Tue Dec 5 | vsLoyola Chicago | W88-77 | 5-2 | .714 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 8 | Sun Dec 10 | atOklahoma St | L57-72 | 5-3 | .625 | - | ESPN2 | Gallagher-Iba Arena · Stillwater, OK |
| 9 | Sat Dec 16 | vsMissouri St | W73-72 | 6-3 | .667 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 10 | Tue Dec 19 | vsMiss Valley St | W79-50 | 7-3 | .700 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 11 | Fri Dec 22 | vsNew Mexico St | W65-59 | 8-3 | .727 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 12 | Fri Dec 29 | vsTBD | W95-54 | 9-3 | .750 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 13 | Thu Jan 4 | vs#15Memphis | L75-78 | 9-4 | .692 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 14 | Sun Jan 7 | atE Carolina | L57-62 | 9-5 | .643 | - | ESPNU | Williams Arena at Minges Coliseum · Greenville, NC |
| 15 | Wed Jan 10 | atCharlotte | L76-84 | 9-6 | .600 | - | | Dale F. Halton Arena · Charlotte, NC |
| 16 | Sun Jan 14 | vsTulane | L87-94 (OT) | 9-7 | .563 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 17 | Wed Jan 17 | vsUTSA | W107-78 | 10-7 | .588 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 18 | Sat Jan 20 | atSMU | L70-103 | 10-8 | .556 | - | | Moody Coliseum · Dallas, TX |
| 19 | Sat Jan 27 | atRice | W85-83 | 11-8 | .579 | - | ESPNU | Tudor Fieldhouse · Houston, TX |
| 20 | Wed Jan 31 | vsWichita St | W79-68 | 12-8 | .600 | - | ESPNU | Donald W. Reynolds Center · Tulsa, OK |
| 21 | Sat Feb 3 | at#20FAU | L70-102 | 12-9 | .571 | - | | FAU Arena · Boca Raton, FL |
| 22 | Wed Feb 7 | vsNorth Texas | L55-68 | 12-10 | .545 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 23 | Sun Feb 11 | vsUAB | L63-70 | 12-11 | .522 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 24 | Wed Feb 14 | atSouth Florida | L50-69 | 12-12 | .500 | - | ESPNU | Yuengling Center · Tampa, FL |
| 25 | Sat Feb 17 | vsRice | W93-82 (OT) | 13-12 | .520 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 26 | Wed Feb 21 | atWichita St | L63-79 | 13-13 | .500 | - | ESPNU | Charles Koch Arena · Wichita, KS |
| 27 | Sat Feb 24 | vsCharlotte | W69-67 | 14-13 | .519 | - | ESPNU | Donald W. Reynolds Center · Tulsa, OK |
| 28 | Wed Feb 28 | atUTSA | L73-89 | 14-14 | .500 | - | | UTSA Convocation Center · San Antonio, TX |
| 29 | Sat Mar 2 | atTemple | W72-67 | 15-14 | .517 | - | | Liacouras Center · Philadelphia, PA |
| 30 | Sat Mar 9 | vs#24South Florida | W76-70 | 16-14 | .533 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 31 | Thu Mar 14 | atE Carolina | L79-84 | 16-15 | .516 | - | ESPNU | Williams Arena at Minges Coliseum · Greenville, NC |
