| 1 | Tue Nov 9 | at Arizona St | L60-76 | 0-1 | .000 | - | | Desert Financial Arena · Tempe, AZ |
| 2 | Thu Nov 11 | vsTBD | W122-78 | 1-1 | .500 | - | | Chiles Center · Portland, OR |
| 3 | Sat Nov 13 | vsAlcorn St | W62-58 | 2-1 | .667 | - | | Chiles Center · Portland, OR |
| 4 | Thu Nov 18 | vsAR-Pine Bluff | W86-74 | 3-1 | .750 | - | | Chiles Center · Portland, OR |
| 5 | Sat Nov 20 | vsMorgan St | W74-63 | 4-1 | .800 | - | | Chiles Center · Portland, OR |
| 6 | Tue Nov 23 | atPortland St | W69-54 | 5-1 | .833 | - | | Viking Pavilion · Portland, OR |
| 7 | Fri Nov 26 | atMontana St | L66-69 | 5-2 | .714 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 8 | Sat Nov 27 | vsSE Missouri St | W74-68 | 6-2 | .750 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 9 | Sun Nov 28 | atIncarnate Word | W77-68 | 7-2 | .778 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 10 | Fri Dec 3 | vsVMI | L82-90 | 7-3 | .700 | - | | Chiles Center · Portland, OR |
| 11 | Mon Dec 13 | vsCal Poly | W78-77 | 8-3 | .727 | - | | Chiles Center · Portland, OR |
| 12 | Wed Dec 15 | atOregon | L71-96 | 8-4 | .667 | - | | Matthew Knight Arena · Eugene, OR |
| 13 | Fri Dec 17 | vsSan Jose St | L78-90 | 8-5 | .615 | - | | Chiles Center · Portland, OR |
| 14 | Sun Dec 19 | atMontana St | L59-61 | 8-6 | .571 | - | | Worthington Arena · Bozeman, MT |
| 15 | Wed Dec 22 | atUC Davis | W65-60 | 9-6 | .600 | - | | University Credit Union Center · Davis, CA |
| 17 | Thu Jan 13 | atSan Diego | L63-68 (OT) | 9-7 | .563 | - | | Jenny Craig Pavilion · San Diego, CA |
| 18 | Sat Jan 15 | atPepperdine | W82-63 | 10-7 | .588 | - | | Firestone Fieldhouse · Malibu, CA |
| 19 | Mon Jan 17 | atLMU | L58-70 | 10-8 | .556 | - | | Gersten Pavilion · Los Angeles, CA |
| 20 | Sat Jan 22 | atBYU | L65-78 | 10-9 | .526 | - | | Marriott Center · Provo, UT |
| 21 | Thu Jan 27 | vsPacific | W64-56 | 11-9 | .550 | - | | Chiles Center · Portland, OR |
| 22 | Sat Jan 29 | at2Gonzaga | L72-104 | 11-10 | .524 | - | | McCarthey Athletic Center · Spokane, WA |
| 23 | Thu Feb 3 | vsSaint Mary's | L54-75 | 11-11 | .500 | - | | Chiles Center · Portland, OR |
| 24 | Sat Feb 5 | vsSan Francisco | L71-74 | 11-12 | .478 | - | | Chiles Center · Portland, OR |
| 25 | Tue Feb 8 | atSan Francisco | W69-68 | 12-12 | .500 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 26 | Sat Feb 12 | vsLMU | W86-76 | 13-12 | .520 | - | | Chiles Center · Portland, OR |
| 28 | Tue Feb 15 | vsTBD | W84-39 | 14-12 | .538 | - | | Chiles Center · Portland, OR |
| 29 | Thu Feb 17 | vsSan Diego | W92-60 | 15-12 | .556 | - | | Chiles Center · Portland, OR |
| 30 | Sat Feb 19 | vsPepperdine | W77-74 | 16-12 | .571 | - | | Chiles Center · Portland, OR |
| 31 | Thu Feb 24 | atPacific | W75-69 | 17-12 | .586 | - | | Alex G. Spanos Center · Stockton, CA |
| 32 | Sat Feb 26 | atSanta Clara | L89-102 | 17-13 | .567 | - | | Leavey Center · Santa Clara, CA |
| 33 | Fri Mar 4 | vsSan Diego | W73-55 | 18-13 | .581 | - | | Orleans Arena · Las Vegas, NV |
| 34 | Sun Mar 6 | atSanta Clara | L67-91 | 18-14 | .563 | - | ESPN2 | Orleans Arena · Las Vegas, NV |
| 33 | Sat Mar 19 | vsNew Orleans | W94-73 | 19-14 | .576 | - | | Chiles Center · Portland, OR |
| 34 | Sat Mar 26 | atSouthern Utah | L66-77 | 19-15 | .559 | - | | America First Events Center · Cedar City, UT |
